A5088273946- Cancer-related Molecular Pathways
- Breast Cancer Treatment Studies
- Spectroscopy and Chemometric Analyses
- Cancer Cells and Metastasis
- Cancer Treatment and Pharmacology
- Cancer Research and Treatments
- Meat and Animal Product Quality
- RNA modifications and cancer
- Ubiquitin and proteasome pathways
- Endometrial and Cervical Cancer Treatments
- Immune Cell Function and Interaction
- Cancer and Skin Lesions
- Melanoma and MAPK Pathways
- Cell death mechanisms and regulation
- Water Quality Monitoring and Analysis
- MicroRNA in disease regulation
- HER2/EGFR in Cancer Research
- Immunotherapy and Immune Responses
- Advanced Breast Cancer Therapies
- Economic and Financial Impacts of Cancer
- Gastric Cancer Management and Outcomes
- Cancer Diagnosis and Treatment
- Soybean genetics and cultivation
- Circular RNAs in diseases
- Cancer Risks and Factors
Third Hospital of Nanchang
2008-2024
Weatherford College
2024
The People's Hospital of Guangxi Zhuang Autonomous Region
2023
Peking University Shenzhen Hospital
2014-2017
Anhui University
2014
Anhui Medical University
2014
Baylor College of Medicine
2012
Evidence suggests that paeoniflorin may be involved in anticancer activities. Here, we have investigated the effects of and correlative mechanisms on anti-invasion anti-metastasis human hepatocellular carcinoma (HCC) cell lines.In current study, applied 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide (MTT) assay to determine proliferative effect HepG2 Bel-7402, two hepatoma lines, established a boyden chamber assay, wound healing adhesion detect quantify invasion, metastasis...
Triple-negative breast cancer (TNBC) is the most aggressive subtype of cancer, characterized by advanced disease stage and poor prognosis. Moreover, due to lack therapeutic markers, TNBC patients can't benefit fully from currently available targeted therapies.To understand molecular basis TNBC, we used gene set enrichment analysis (GSEA) screen out altered functional module in publicly microarray data studied association candidate with development.We found that proteasome was significantly...
The solute carrier (SLC) 7 family genes play central roles in cancer cell metabolism as glucose and glutamate transporters. However, their expression prognostic value breast (BC) remains to be elucidated.Clinical data from BC patients were downloaded Cancer Genome Atlas (TCGA) the Kaplan-Meier (KM) plotter database. mechanisms underlying association between SLC7A overall survival (OS) explored using Cox regression log-rank tests. ESTIMATE gives a measure of immune-cell infiltrates....
Introduction: The purpose of our research was to evaluate MT1JP in breast cancer. Material and Methods: For clinical purpose, tissues were collected, a correlation analysis ofMT1JP miRNA-214 gene expressions conducted. Using an vitro study, MDA-MB-231 MCF-7 cell lines used as objects research. Colony, flow cytometry, TUNEL, transwell, adhesion wound healing assay discuss the biological activities cells. In vivo tumor weight volume measured, apoptosis measured by TUNEL assay. relative...
Several studies have analyzed the relationship between body mass index (BMI) and prognosis of breast cancer (BC). However, whether their is linear or curvilinear remains unclear. This cohort study examined specific BMI BC outcomes. retrospective included 1049 patients from March 7, 2013 through December 31, 2019 in a hospital. Kaplan-Meier curves, multivariate Cox proportional models, restricted cubic spline (RCS) was used to analysis overall survival (OS) cancer-specific (BCSS) analyzed....
Non-islet cell tumor hypoglycemia (NICTH) generally refers to caused by tumors other than islet tumors. Although is a common clinical emergency, NICTH rarely occurs in patients with breast cancer.A 47-year-old woman presented repeated lobulated tumor.Hypoglycemic symptoms occurred many times during fasting and the early morning. Insulin C-peptide levels were decreased; insulin-like growth factor (IGF)-II: IGF-I was greater 10. Postoperative pathology revealed breast. After excluding causes...
Background: Extramammary Paget disease is a relatively rare and less malignant intraepithelial adenocarcinoma. t found in areas with abundant distribution of apocrine sweat glands such as the external genitalia, perianal area, fewer armpits. The progresses slowly prone to misdiagnosis clinical practice. Methods: We retrospectively analyzed female patient. She had left axillary mass for more than 2 years. Recently, increased surface skin was ulcerated. Then she went Jiangxi Provincial...
A retrospective study on 90 eligible HER2+ ductal carcinoma
<abstract> <b>Abstract.</b> Freshness of meat directly affects the economic benefits and vital interests people. Meat color (L*, a*, b*), pH value are important reference attributes for evaluating freshness. This paper attempts to measure in pork using a new self-designedportable low cost detection device. The device was composed Light Emitting Diode (LED) arrays with six different wavelengths 460, 525, 570, 590, 610, 630nm forming ring light source, silicon photodiode as detector embedded...
<abstract> <b><sc>Abstract.</sc></b> Potato blackheart is a kind of internal physiological disease which couldn‘t be found by people from the surface. In order to identify potato without destruction and more accurately, sorting system could collect light transmission images tubers automatically detect sort potatoes with was developed. The sources used in this research were emitting diodes wavelength 705 nm. part tuber weaken transmitted effectively than normal part, forming dark-gray spot...
<abstract> <b><sc>Abstract.</sc></b> Meat freshness is directly related to the health of consumers, and total volatile basic nitrogen (TVB-N) content an important reference index for evaluating pork freshness. This paper attempted measure TVB-N assessing using a new self-developed portable low cost detection device designed by ourselves basing on near infrared technique. The front-end part this was integrated component containing ring light source which included 64 Light Emitting Diode (LED)...
<abstract> <b><sc>Abstract.</sc></b> This paper put forward a method of using image technology to identify the vitality vegetable seed. Tomato as kind important was used for research. Seed vigor is an indicator measuring quality, which integrated performance determining activity level and behavior characteristics seed during germination emergence. Traditional identification methods mainly include seedling grading method, determination growth rate resistance cold, frozen accelerated ageing...
e11576 Background: Triple-negative breast cancer (TNBC) is a high-grade with poor prognosis characterized by lack of ER and PR expression no HER2 overexpression. Differences in survival economic burden between metastatic TNBC (mTNBC) non-TNBC (mNon-TNBC) are not well understood. Objective:To measure compare survival, healthcare utilization, costs mTNBC mNon-TNBC. Methods: This retrospective study used the Impact Intelligence Oncology Management system linked 1999-2009 managed care claims...
Objective To evaluate the effect of neoadjuvant chemotherapy (NAC) by investigating expression cyclin D1 in human breast cancer before and after NAC.Methods Eighty-four cases were diagnosed core biopsies.The level tissues was measured immunohistochemical envision two-step method NAC (pirarubicin docetaxel regimen for 3-4 cycles).Results Complete remission (CR) occurred 4 84 patients (4.76 ％) with 2 pathological complete response cases,partial (PR) 54 (64.29 ％),stability (SD) 26 (30.95 no...
Abstract Cancer initiating/stem cells are thought to be responsible for treatment-resistance, disease-recurrence and metastasis. Current breast cancer stem cell markers lack direct correlation with function, which makes the targeted therapeutic design difficult. The STAT3 pathway is a critical regulator of function normal evidence accumulating its important role in cells, as well associated “niche” cells. However, due method pathway-activity-based live separation, whether functions...
Introduction It has been unclear that ERK play the effects and relative mechanism in breast cancer development. The purpose of this work was to discuss effect mechanisms. Material methods Evaluating CD59 proteins expression difference tissue from patients by IHC assay. Using MCF-7 MDA-MB-231 cell lines which were as target our study. In vitro study, evaluating biological activities including proliferation, apoptosis, cycle, invasion, adherent migration MTT, clone test, TUNEL assay, flow...