Zepeng Yu

ORCID: 0000-0003-0872-2510
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Research Areas
  • Immune cells in cancer
  • Nanoplatforms for cancer theranostics
  • Pelvic floor disorders treatments
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Extracellular vesicles in disease
  • Cancer Immunotherapy and Biomarkers
  • Urinary Bladder and Prostate Research
  • Urinary Tract Infections Management
  • Family and Disability Support Research
  • Cancer Cells and Metastasis
  • Nanoparticle-Based Drug Delivery
  • Glioma Diagnosis and Treatment
  • Immune Cell Function and Interaction
  • Brain Tumor Detection and Classification
  • Video Surveillance and Tracking Methods
  • Radiomics and Machine Learning in Medical Imaging
  • Spinal Cord Injury Research
  • Cancer, Hypoxia, and Metabolism
  • Anomaly Detection Techniques and Applications
  • Fire Detection and Safety Systems
  • Cerebral Palsy and Movement Disorders

Nanjing Medical University
2022-2025

Suzhou Municipal Hospital
2023-2025

Sun Yat-sen University
2022

Sun Yat-sen University Cancer Center
2022

Abstract Purpose The present research aimed to investigate the effects of a self‐efficacy‐centered self‐management program on persons with neurogenic bladder (NGB) after spinal cord injury (SCI). Design A randomized controlled trial. Materials and Methods Eighty‐two individuals NGB (SCI) were into either control or intervention group. group received standard admission discharge education follow‐up. program. Self‐efficacy was assessed at preintervention, 4, 8, 12 weeks post‐intervention....

10.1111/jjns.12642 article EN cc-by-nc Japan Journal of Nursing Science 2025-01-01

OBJECTIVE The aim of this study was to build a convolutional neural network (CNN)–based prediction model glioblastoma (GBM) molecular subtype diagnosis and prognosis with multimodal features. METHODS In total, 222 GBM patients were included in the training set from Sun Yat-sen University Cancer Center (SYSUCC) 107 validation SYSUCC, Xuanwu Hospital Capital Medical University, First Jilin University. trained MR images (pre- postcontrast T1-weighted T2-weighted images), corresponding MRI...

10.3171/2022.10.jns22801 article EN Journal of neurosurgery 2022-12-23

Background It has been demonstrated that cryoablation (Cryo) causes specific T-cell immune responses in the body; however, it is not sufficient to prevent tumor recurrence and metastasis. In this report, we evaluated changes microenvironment (TIME) distant tissues after Cryo investigated immunosuppressive mechanisms limit efficacy of Cryo.Methods Bilateral mammary models were established mice, first observed dynamic cells cytokines at different time points Cryo. Then, confirmed upregulation...

10.1080/02656736.2022.2164625 article EN cc-by International Journal of Hyperthermia 2023-03-26

Tumor-associated macrophages (TAMs)-based immunotherapy is a promising strategy. Since TAMs are mainly composed of M2-type macrophages, they have promoting effect on tumor growth, invasion, and metastasis. contain specific receptor CD163 their surface, providing prerequisite for active targeting to TAMs. In this study, we prepared monoclonal antibody modified doxorubicin-polymer prodrug nanoparticles (abbreviated as mAb-CD163-PDNPs) with pH responsiveness targeted delivery. First, DOX was...

10.3390/pharmaceutics15041241 article EN cc-by Pharmaceutics 2023-04-14

To test the contributions of self-efficacy, resilience, social support, and negative moods (i.e., anxiety, depression) to patient activation among persons with spinal cord injury (SCI).One hundred twenty-two participants SCI were recruited from surgery department at a large general hospital. During period before discharge after surgery, standardized self-assessment questionnaires used collect data on activation, depression, demographics (age, gender, education, marital status),...

10.1111/jjns.12532 article EN cc-by Japan Journal of Nursing Science 2023-03-25

10.1016/j.engappai.2024.108898 article EN Engineering Applications of Artificial Intelligence 2024-07-07

Background Cryoablation (Cryo) is a minimally invasive treatment for tumors. Cryo can activate the body's immune response, although it typically weak. The response induced by in hepatocellular carcinoma (HCC) poorly understood. PD-1 and CTLA-4 monoclonal antibodies are checkpoint inhibitors used immunotherapy combined use of these with may enhance effect.

10.1080/02656736.2024.2373319 article EN cc-by International Journal of Hyperthermia 2024-07-02

Abstract Study design: A double-blinded randomized controlled trial. Objective The present research aimed to investigate the effects of a self-efficacy-centred self-management program on persons with neurogenic bladder (NGB) after spinal cord injury (SCI). Setting: surgery department Third Affiliated Hospital Soochow University, Changzhou, China. Methods Eighty-two individuals NGB SCI were into control or intervention group. group received standard admission and discharge education...

10.21203/rs.3.rs-1900164/v1 preprint EN cc-by Research Square (Research Square) 2022-08-08
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