A5036587412- Central Venous Catheters and Hemodialysis
- Vascular Procedures and Complications
- Lung Cancer Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Hepatocellular Carcinoma Treatment and Prognosis
- Medical Imaging and Pathology Studies
- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Lymphatic Disorders and Treatments
- Pleural and Pulmonary Diseases
- Tuberous Sclerosis Complex Research
- Vascular Malformations and Hemangiomas
- Uterine Myomas and Treatments
- Lung Cancer Treatments and Mutations
- Hemodynamic Monitoring and Therapy
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Vascular anomalies and interventions
- Cancer Mechanisms and Therapy
- MRI in cancer diagnosis
- Diverticular Disease and Complications
- Extracellular vesicles in disease
- Characterization and Applications of Magnetic Nanoparticles
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Maternal and fetal healthcare
- Cardiac Arrhythmias and Treatments
Soochow University
2015-2025
Second Affiliated Hospital of Soochow University
2015-2025
Seoul National University
2024
Seoul National University Bundang Hospital
2024
Shandong Provincial QianFoShan Hospital
2022
Shandong First Medical University
2022
Puer University
2020
Soochow University
2019
Nanjing Medical University
2018
Jilin University
2017
This study aimed to assess the feasibility and safety of robotic-assisted navigation system for percutaneous transthoracic needle biopsy (PTNB), compare it with conventional freehand technique, evaluate its generalizability across operators varying experience levels. After excluding 5 patients in whom PTNB could not be performed due technical problems, a total 50 200 who puncture were included. Using propensity score matching (PSM) match two groups simulate randomized controlled scenario....
The purpose of the study is to retrospectively evaluate safety and efficacy microwave ablation (MWA) for treatment ground-glass opacity (GGO)-lung adenocarcinoma.From December 2013 June 2017, a total 51 patients (22 males 29 females, mean age 69.4 ± 10.1 years) were included in this study, with lung adenocarcinoma lesions showing GGO (mean long-axis diameter 18.7 6.05 mm). They received 52 sessions percutaneous computed tomography-guided (CT-guided) MWA. First, was histologically defined by...
IGF2BP1 overexpression promotes hepatocellular carcinoma (HCC) progression. Long non-coding RNA LIN28B-AS1 directly binds to IGF2BP1. In the present study, and expression their potential functions in HCC cells were tested. Genetic strategies applied interfere expression, cell survival, proliferation apoptosis analyzed. We show that is expressed established/primary human tissues. RNA-immunoprecipitation (RIP) pull-down results confirmed associated with protein cells. silencing (by targeted...
Microwave ablation (MWA) is an effective and safe approach for the treatment of ground-glass nodule (GGN)-like lung cancer, but long-term follow-up warranted. Therefore, this multi-center retrospective study aimed to evaluate results MWA peripheral GGN-like cancer with a follow-up.From June 2013 January 2018, total 87 patients (47 males 40 females, mean age 64.6 ± 10.2 years) lesions showing GGN (mean long axis diameter, 17 5 mm) underwent computed tomography (CT)-guided percutaneous MWA....
The aim of this study was to comparatively analyze the therapeutic effects uterine artery embolization (UAE) and laparoscopic myomectomy (LM) on fibroids determine which treatment method is more beneficial for patients. A retrospective conducted 396 patients who underwent UAE (n = 153) or LM 243) from April 2010 September 2019. After 1:1 propensity score matching (PSM), a comparative analysis surgical trauma magnitude, postoperative recovery time, improvement in associated symptoms quality...
This study aimed to evaluate non-tumor liver parenchymal injury in advanced gastric cancer patients undergoing transarterial infusion chemotherapy (TAI) using imaging parameters and biomarkers, providing objective evidence for early detection of drug-induced injury. A retrospective analysis was conducted on 52 who received TAI at our center from July 2015 2023. Abdominal CT images laboratory data were collected before after treatment. Imaging postprocessing software used measure the...
Hepatocellular carcinoma is one of the most challenging malignancies and has high incidence mortality rates worldwide. Digital subtraction angiography (DSA)-guided hepatic arterial infusion standard chemotherapeutic agent oxaliplatin (OXA) advantages both precision efficacy, making it an important therapeutic strategy for advanced-stage liver cancer. However, patients receiving this treatment still face severe systemic toxicity poor tolerability oxaliplatin. In study, we compared with novel...
Objective Camrelizumab is a newly developed program-death receptor one inhibitor; the real-world evidence about its application in hepatocellular carcinoma (HCC) treatment lacking. Therefore, this prospective, multi-center, study evaluated efficacy and safety of camrelizumab plus transarterial chemoembolization (TACE) treating intermediate-to-advanced HCC patients. Methods This consecutively enrolled 101 intermediate to advanced All patients received camrelizumab-based within 30 days...
Hepatocellular carcinoma (HCC) is a highly aggressive and lethal neoplasm with poor prognosis. The aim of this study to investigate the anticancer activity cinobufotalin, bufadienolide isolated from toad venom, in cultured HCC cells, underlying mechanisms. We found that cinobufotalin (at nmol/L) significantly inhibited cell growth survival while inducing considerable apoptosis. Further, sphingosine kinase 1 (SphK1) induced pro-apoptotic ceramide production. Ceramide synthase-1 small hairpin...
Clinical xenotransplantations have been hampered by human preformed antibody-mediated damage of the xenografts. To overcome biological incompatibility between pigs and humans, one strategy is to remove major antigens [Gal, Neu5Gc, Sd(a)] present on pig cells tissues. Triple gene (GGTA1, CMAH, β 4GalNT2) knockout (TKO) were produced in our laboratory CRISPR-Cas9 targeting. investigate antigenicity reduction TKO pigs, expression levels these three xenoantigens cornea, heart, liver, spleen,...
Background It has been demonstrated that cryoablation (Cryo) causes specific T-cell immune responses in the body; however, it is not sufficient to prevent tumor recurrence and metastasis. In this report, we evaluated changes microenvironment (TIME) distant tissues after Cryo investigated immunosuppressive mechanisms limit efficacy of Cryo.Methods Bilateral mammary models were established mice, first observed dynamic cells cytokines at different time points Cryo. Then, confirmed upregulation...
One type of the temperature-responsive and magnetic nanomicelles was synthesized based on SPIONs (superparamagnetic iron oxide nanoparticles) biocompatible polymer-Pluronic F127 or its copolymer with poly(DL-lactic acid) (F127–PLA) via a facile chemical conjugation method. The were characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray powder diffraction (XRD), thermogravimetric analysis (TGA), vibrating sample magnetometer (VSM), dynamic light scattering measurements (DLS),...
Two lipid‐solid dispersion loading Norcantharidin sustained‐released microspheres of alginate‐chitosan (NCTD/LSD‐ACMs) were prepared via the emulsification‐gelation method. The effects for transarterial hepatic chemoembolization evaluated in VX2 rabbit liver cancer model. animal model was established by biopsy needle, divided randomly into four groups, and disposed with three preparations including NCTD/LSD‐ACMs (60–120 μm), NCTD/LSD‐ACMs(120–200 NCTD solution through arteries compared...
Abstract Background Microneedles are tiny needles, typically ranging from tens to hundreds of micrometers in length, used various medical procedures and treatments. The tested device named “CELLADEEP Patch” a dissolvable microneedle therapy system (MTS), made hyaluronic acid collagen. And the iontophoresis technique is also applied system. study aimed evaluate effectiveness skin improvement. Methods Ex vivo human‐derived tissue models were this they divided into three different groups,...