A5012514567- Wound Healing and Treatments
- Electrospun Nanofibers in Biomedical Applications
- Nanoplatforms for cancer theranostics
- Body Composition Measurement Techniques
- Dermatologic Treatments and Research
- Muscle Physiology and Disorders
- Polymer Surface Interaction Studies
- Lymphatic System and Diseases
- Tissue Engineering and Regenerative Medicine
- Advanced biosensing and bioanalysis techniques
- Nutrition and Health in Aging
- Conducting polymers and applications
- Silk-based biomaterials and applications
- Infrared Thermography in Medicine
- Advancements in Transdermal Drug Delivery
- Bee Products Chemical Analysis
- Planarian Biology and Electrostimulation
- Antimicrobial agents and applications
- Periodontal Regeneration and Treatments
- Biosensors and Analytical Detection
- Polymer composites and self-healing
- Dermatology and Skin Diseases
- Breast Implant and Reconstruction
- Facial Rejuvenation and Surgery Techniques
- Skin and Cellular Biology Research
Seoul National University Bundang Hospital
2022-2024
Seoul National University
2022-2024
Korea National University of Transportation
2021
Hydrocolloid dressings are an important method for accelerating wound healing. A combination of a hydrocolloid and nanoparticles (NPs), such as gold (Au), improves the healing rate, but Au-NPs expensive unable to block ultraviolet (UV) light. Herein, we combined zinc oxide (ZnO-NPs) with hydrocolloids less more effective UV-blocking treatment wounds. Using Sprague-Dawley rat models, showed that, during 10-day treatment, patch covered ZnO-NPs (ZnO-NPs-HC) macroscopically microscopically...
Background/Aim: Chitosan-based functional materials have attracted considerable attention worldwide for applications in wound healing, especially skin due to their efficiency hemostasis, anti-bacterial, and regeneration. Various chitosan-based products been developed healing applications, but most of these face limitations either efficacy or cost-effectiveness. Therefore, there is a need develop unique material that can handle all concerns be utilized acute chronic wounds. This study...
Abstract Background Microneedles are tiny needles, typically ranging from tens to hundreds of micrometers in length, used various medical procedures and treatments. The tested device named “CELLADEEP Patch” a dissolvable microneedle therapy system (MTS), made hyaluronic acid collagen. And the iontophoresis technique is also applied system. study aimed evaluate effectiveness skin improvement. Methods Ex vivo human‐derived tissue models were this they divided into three different groups,...
Abstract Background Injectable filler, a nonsurgical beauty method, has gained popularity in rejuvenating sagging skin. In this study, polydioxanone (PDO) was utilized as the main component of ULTRACOL200 filler that helps stimulate collagenesis and provide skin radiant effects. The study aimed to evaluate compare effectiveness with other commercialized products visually improving dermatological problems. Methods Herein, 31 participants aged between 20 59 years were enrolled study. 1 mL...
The regulation of proinflammatory mediators has been explored to promote natural healing without abnormal inflammation or autoimmune response induced by their overproduction. However, most efforts control these have relied on pharmacological substances that are directly engaged in biological cycles. It is believed functional porous materials removing target provide a new way the process using adsorption mechanisms. In this study, Zr-based metal-organic frameworks (MOF)-808 (Zr
Electrosurgical electrodes are the main dissecting devices widely used for surgeries throughout world. The present study aimed to evaluate thermal injury and safety within animals' organs following a minimally invasive electrosurgery technique with electrosurgical electrode AE40-300 (LIPO) AE20-80 (LIFT). To ensure effective application of in clinical environment, it is crucial minimize heat-induced nearby tissues. In this study, skin, liver, kidney, femoral muscle dissected from 9 minipigs...
Introduction Wound healing is a complex process involving multiple stages, including inflammation, proliferation, and remodeling. Effective wound management strategies are essential for accelerating improving outcomes. The CELLADEEP patch, incorporating iontophoresis therapy microneedle technology, was evaluated its potential to enhance the process. Methods This study utilized full-thickness skin defect model in Sprague-Dawley rats, researchers compared outcomes between rats treated with...
Allotransplantation, performed using an acellular dermal matrix (ADM), plays a significant role in the cultivation of constituted and damaged organs clinical. Herein, we fabricated innovative ADM for allografting derived from decellularized human skin by utilizing supercritical fluid carbon dioxide to eliminate immunogenic components. By histological staining, product demonstrated successful removal cellular constituents without exerting any harmful influence on extracellular matrix. The...
In situ wireless monitoring for cell proliferation and detachment kinetics was conducted using pH-responsive zwitterionic polymer dots (Z-PDs), based on changes in electrochemical signals derived from Z-PD-coated substrates via the interaction of charges transferred between Z-PDs cells. were found to be a potent means monitor manipulate adhesion because their high sensitivity over wide range pH conditions, modification coated confirmed system. At neutral pH, sensors exhibited π–π stacking...
Abstract Lymphedema is a disease that refers to tissue swelling caused by an accumulation of protein-rich fluid usually drained through the lymphatic system. Detection lymphedema often based on expensive diagnoses such as bioimpedance spectroscopy, shear wave elastography, computed tomography, etc. In current machine learning models for prediction, reliance observable symptoms reported patients introduces possibility errors in patient-input data. Moreover, these are absent during initial...
Human skin-derived ECM aids cell functions but can trigger immune reactions; therefore it is addressed through decellularization. Acellular dermal matrices (ADMs), known for their regenerative properties, are used in tissue and organ regeneration. ADMs now play a key role plastic reconstructive surgery, enhancing aesthetics reducing capsular contracture risk. Innovative decellularization with supercritical carbon dioxide preserves quality clinical use. The study investigated the...
Abstract In this study, scalp tissues from Korean adults between 20 and 80 without skin disease were used. Scalp processed, hair follicles isolated cultured with different treatments (including Bioscalp, Ultra Exo Booster, S Line Plus) V company. Over 12 days, observations measurements of follicle characteristics recorded at intervals (Days 0, 3, 6, 9, 12). The study assessed the impact these substances on growth morphology. combined Booster Plus, showed significant elongation in ex vivo....
Aims: The objective of this study is to provide a reliable strategy for the diagnosis sarcopenia based on complementary combination biomarkers from various approaches.Main methods: A total 10 C57BL/6J mice were used experiment, in which 5 young (YM) at 24 weeks old and aged (AM) 88 old. Extracted features-based digital electromyography activity tibialis anterior muscles evaluated by using receiver operating characteristic analysis. tissular proteins circulating hormones chemical investigated...
Abstract Background: Lymphedema is a disease thatrefers to tissue swelling caused by an accumulation of protein-rich fluid that usually drained through the lymphatic system. Detection lymphedema often based on expensive diagnoses such as bioimpedance spectroscopy, shear wave elastography, computed tomography, etc. Applications data science and machine learning in predicting medical conditions offered support for doctors patients early detection diseases. Although current studies proposed...