Jian Zhang

ORCID: 0000-0003-3664-5807
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About
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Research Areas
  • Spinal Fractures and Fixation Techniques
  • Spine and Intervertebral Disc Pathology
  • Ectopic Pregnancy Diagnosis and Management
  • Hip and Femur Fractures
  • Bone fractures and treatments
  • Reproductive System and Pregnancy
  • Gynecological conditions and treatments
  • Reproductive Health and Contraception
  • Pelvic and Acetabular Injuries
  • Orthopedic Surgery and Rehabilitation
  • Maternal and Perinatal Health Interventions
  • Uterine Myomas and Treatments
  • Maternal and fetal healthcare
  • Cervical and Thoracic Myelopathy
  • Orthopaedic implants and arthroplasty
  • Nitric Oxide and Endothelin Effects
  • Pregnancy-related medical research
  • Endometriosis Research and Treatment
  • Assisted Reproductive Technology and Twin Pregnancy
  • Fetal and Pediatric Neurological Disorders
  • Cerebrovascular and Carotid Artery Diseases
  • Neuroscience and Neural Engineering
  • Intracranial Aneurysms: Treatment and Complications
  • Diagnosis and Treatment of Venous Diseases
  • Pregnancy and preeclampsia studies

Soochow University
2017-2025

Second Affiliated Hospital of Soochow University
2017-2025

Lanzhou University
2022-2024

Lanzhou University Second Hospital
2022-2024

The First Affiliated Hospital, Sun Yat-sen University
2006-2024

Zhongshan Hospital
2006-2024

Fudan University
2003-2024

Sun Yat-sen University
2006-2024

Shandong University
2024

Air Force Medical University
1998-2024

Importance Approximately 60% of women develop a uterine niche after cesarean delivery (CD). A is associated with various gynecological symptoms including abnormal bleeding, pain, and infertility, but there little consensus in the literature on distinction between sonographic finding constellation symptoms. Objective To achieve defining clinical condition that constitutes symptomatic agree upon diagnostic criteria uniform nomenclature for this condition. Design, Setting, Participants based...

10.1001/jamanetworkopen.2023.5321 article EN cc-by-nc-nd JAMA Network Open 2023-03-29

This study aimed to assess the feasibility and safety of robotic-assisted navigation system for percutaneous transthoracic needle biopsy (PTNB), compare it with conventional freehand technique, evaluate its generalizability across operators varying experience levels. After excluding 5 patients in whom PTNB could not be performed due technical problems, a total 50 200 who puncture were included. Using propensity score matching (PSM) match two groups simulate randomized controlled scenario....

10.1038/s41598-025-87987-5 article EN cc-by-nc-nd Scientific Reports 2025-02-18

<h2>Abstract</h2><h3>Objective</h3> To explore the risk factors for ectopic pregnancy (EP) in women with planned pregnancy. <h3>Study design</h3> This case–control study was conducted and included 900 diagnosed EP (case group) 889 intrauterine (IUP) as control group matched terms of age gestational week. Socio-demographic characteristics, reproductive history, gynecological surgical previous contraceptive use, history infertility were compared between two groups. Blood samples collected from...

10.1016/j.ejogrb.2014.07.049 article EN cc-by-nc-nd European Journal of Obstetrics & Gynecology and Reproductive Biology 2014-08-08

The current coronavirus disease (COVID-19) pandemic is holding the world in its grip. Epidemiologists have shown that mortality risks are higher when health care system subjected to pressure from COVID-19. It therefore of great importance maintain providers and prevent contamination. An important group who will be required treat patients with COVID-19 during semiacute surgery. There concerns laparoscopic surgery increases risk contamination more than open surgery; therefore, balancing safety...

10.2196/18928 article EN cc-by JMIR Public Health and Surveillance 2020-05-13

Objective We aimed to study the relationship between ferroptosis proteins and reproductive outcomes of infertile patients with PCOS construct related prognostic model. Methods These endometrium samples were collected from 33 women 7 control successful pregnancies at Reproductive Center Lanzhou University Second Hospital, September 2019 2020. The 40 patients’ was identified differentially expressed (DEPs) using liquid chromatography tandem mass spectrometry. Kyoto Encyclopedia Genes Genomes...

10.3389/fendo.2022.871945 article EN cc-by Frontiers in Endocrinology 2022-07-14

Accumulating evidence strongly support the key role of NLRP3-mediated pyroptosis in pathogenesis and progression vascular endothelial dysfunction associated with diabetes mellitus. Various studies have demonstrated that activation or upregulation Silent Information Regulation 2 homolog (SIRT2) exerts inhibitory effect on expression NLRP3. Although 1,8-cineole has been found to protect against cardiovascular diseases, its mechanism diabetic angiopathy remain unknown. Therefore, aim this study...

10.1016/j.biopha.2024.117085 article EN Biomedicine & Pharmacotherapy 2024-07-06

The use of membrane-based guided bone regeneration techniques has great potential for single-stage reconstruction critical-sized defects. Here, a multifunctional membrane combining flexible elasticity, electrical stimulation (ES) and osteoinductive activity is developed by in situ doping MXene 2D nanomaterials with conductive functionality β-TCP particles into Poly(lactic acid-carbonate (PDT) composite nano-absorbable (P/T/MXene) via electrostatic spinning technique. good feasibility due to...

10.1002/smll.202405311 article EN Small 2024-08-15

Increasing epidemiological evidence has reported that various factors are associated with migraine risk and subtypes. Nevertheless, definitive conclusions regarding whether the putative modifiable causally related to pathogenesis of have not been drawn. Using single-nucleotide polymorphisms as instrumental variables, we conducted a two-sample Mendelian randomization (MR) analysis investigate causal effects 38 factors, including dietary nutrients, lifestyle cardiometabolic diseases, traits,...

10.1080/01616412.2025.2504717 article EN Neurological Research 2025-05-14

Abstract Cases of ectopic pregnancy (EP) following levonorgestrel emergency contraception (LNG-EC) failure have been reported continuously, but whether there is an association between EP risk and LNG-EC unclear. We concluded a case-control study to explore this by recruiting 2,411 patients as case group 2,416 women with intrauterine 2,419 non-pregnant control groups. Odds ratios (ORs) their 95% confidential intervals (CIs) were calculated adjusted for potential confounding factors. Previous...

10.1038/srep08487 article EN cc-by Scientific Reports 2015-02-12

With the implementation of two-child policy in China, more couples have expressed desire to another child. We conducted this study evaluate incidence infertility and risk factors intending a first second

10.1186/s12978-022-01459-x article EN cc-by Reproductive Health 2022-07-08

Ruptured ectopic pregnancy (REP), a complication caused by aberrant implantation, deep invasion, and overgrowth of embryos in fallopian tubes, could lead to rupture tubes accounts for 4%-10% pregnancy-related deaths. The lack phenotypes rodents hampers our understanding its pathological mechanisms. Here, we employed cell culture organoid models investigate the crosstalk between human trophoblast development intravillous vascularization REP condition. Compared with abortive (AEP), size...

10.1016/j.celrep.2023.112546 article EN cc-by Cell Reports 2023-05-23

The immunological function of patients with malignant tumors may be suppressed during the perioperative period. However, details on effects transcutaneous electrical acupoint stimulation (TEAS) are relatively lacking. We designed this study to examine TEAS non-small cell lung cancer (NSCLC) Participants (n = 144) were enrolled and randomly assigned into group or sham TEAS. bilateral Feishu (BL13), Hegu (L14), Zusanli (ST36) was performed continuously throughout procedure. primary outcome...

10.1177/1533033818806477 article EN cc-by-nc Technology in Cancer Research & Treatment 2018-01-01

The aim of the present study was to determine efficacy microsurgery treatment for parasagittal meningioma in central gyrus region. A microsurgical technique used treat 26 patients with large Rolandic and draining veins peritumoral normal brain tissue were retained, associated sagittal sinus appropriately protected. Simpson grade I, II or III resection performed 8 (30.8%), 12 (46.2%) 6 (23.1%) patients, respectively, no post‑operative mortalities. Following treatment, 9 exhibited...

10.3892/ol.2013.1429 article EN Oncology Letters 2013-06-26

Background: Type 2 diabetes mellitus (T2DM) and inflammatory bowel disease (IBD) have been associated, according to various epidemiological research. This study uses Mendelian randomization (MR) investigate the causal link between T2DM IBD. Methods: To relationship IBD risk using European population data from genome-wide association (GWAS) summary datasets, we constructed a two-sample MR evaluate genetically predicted impacts of liability towards outcomes on risk. As instrumental variables...

10.3389/fgene.2024.1325401 article EN cc-by Frontiers in Genetics 2024-02-16

End-to-side (ETS) neurorrhaphy has been applied in the repair of peripheral nerve injuries and babysitter procedures. However, long-term changes donor muscle after ETS remain unknown. This study was designed to investigate a rat model. Sixty Lewis rats were equally allocated into three groups 20 rats. The peroneal divided. In Group A, end-to-end (ETE) performed. B, performed an epineurial window on tibial nerve. C, with 40% partial neurectomy. following data obtained at 6, 12, 18, 24 weeks...

10.1002/micr.22167 article EN Microsurgery 2013-09-06

ObjectiveTo determine whether hysteroscopic niche resection (HNR) and expectant management are suitable in women with fertility desire a residual myometrium thickness (RMT) ≥ 2.5 mm.Study designThis retrospective cohort study was conducted at International Peace Maternity Child Health Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China between September 2016 December 2021. We reported the outcomes (with RMT mm) who received HNR or management.ResultsWe studied 166...

10.1016/j.ejogrb.2023.03.009 article EN cc-by-nc-nd European Journal of Obstetrics & Gynecology and Reproductive Biology 2023-03-13

Reports of ectopic gestation after failure emergency contraceptive pills have thus far been rare, although the use various types is becoming more and popular world-wide. We report two cases following levonorgestrel as over-the-counter pills. The women personally purchased at a drugstore took them routinely. Clinicians should be aware possibility an when pill fails. recommend to full established service networks enhance education dissemination information on contraception. Additionally,...

10.1080/ejc.8.4.225.228 article EN The European Journal of Contraception & Reproductive Health Care 2003-01-01

Abstract The purpose of this experiment was to determine the stimulating and recording characters fascicular physioelectrical signals in activity peripheral nerves by longitudinally implanted intrafascicular electrodes (LIFEs) a rabbit sciatic nerve model, discuss future application LIFEs functional electrical stimulation (FES) control electric arm prosthesis. In methodology, were inserted into fasciculus rabbits used as electrodes, respectively. Motor‐evoked potentials (MEPs), cortical...

10.1002/micr.10116 article EN Microsurgery 2003-01-01

This study aims to investigate the impact of Kuntai Capsules(KTC) on polycystic ovarian syndrome(PCOS) rat models and explore underlying mechanism. Fifty female SD rats were randomly divided into five groups(10 in each group), including control group, model low-, medium-, high-dose KTC group. Except for other groups injected with dehydroepiandrosterone(DHEA) combined a high-fat diet(HFD) induce PCOS 28 days. 0.315, 0.63, 1.26 g·kg~(-1)·d~(-1) was dissolved same amount normal saline given by...

10.19540/j.cnki.cjcmm.20231115.501 article EN PubMed 2024-02-01
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