A5056059212- Insect and Arachnid Ecology and Behavior
- Plant and animal studies
- Insect and Pesticide Research
- Soft Robotics and Applications
- Adhesion, Friction, and Surface Interactions
- Modular Robots and Swarm Intelligence
- Cancer-related molecular mechanisms research
- Advanced Materials and Mechanics
- Advanced Sensor and Energy Harvesting Materials
- Robot Manipulation and Learning
- Retinal Diseases and Treatments
- Glaucoma and retinal disorders
- Ferroptosis and cancer prognosis
- MicroRNA in disease regulation
- Autophagy in Disease and Therapy
- Biomimetic flight and propulsion mechanisms
- Flavonoids in Medical Research
- Structural Analysis and Optimization
- Plant Reproductive Biology
- Fossil Insects in Amber
- Calcium Carbonate Crystallization and Inhibition
- RNA modifications and cancer
- Robotic Locomotion and Control
- Circular RNAs in diseases
- Retinal Imaging and Analysis
Sun Yat-sen University
2018-2025
Sichuan Agricultural University
2022-2025
West China Hospital of Sichuan University
2025
Eye & ENT Hospital of Fudan University
2023-2024
Beijing Anzhen Hospital
2022-2024
Capital Medical University
2022-2024
Beijing Institute of Water
2023-2024
Inner Mongolia University of Technology
2024
Sir Run Run Shaw Hospital
2024
Tianjin University
2023-2024
A soft gripper inspired by the glowing sucker octopus (Stauroteuthis syrtensis)' highly evolved grasping capability enabled umbrella-shaped dorsal and ventral membrane between each arm is presented here, comprising of a 3D-printed linkage mechanism used to actuate modular mold silicone-casting suction disc deform. The grasp can lift objects using generated pump in disc. Moreover, protruded funnel-shaped end deformed suctorial mouth adapt smooth rough surfaces. Furthermore, when contacts...
Abstract Interfacial solar steam generation can produce clean water in an environmentally friendly and efficient way. The evaporator employing graphene as a photothermal conversion material represents excellent paradigm within the realm of interfacial evaporators. However, existing materials exhibit certain degree hydrophobicity are associated with intricate manufacturing processes. Hence, study proposes hydrophilic composite graphene‐based incorporating CuO, which is fabricated through...
Cable-driven continuum robots exhibit accessing and manipulation capabilities in constrained cluttered environments that are unachievable for traditional composing of discrete links joints. However, the existing structured by non-scalable backbones monofunctional, merely capable providing bending degree freedom, not allowing regional elongation is necessary dexterous manipulation. In this paper, we present a particular tensegrity topology robotic design with an additional stretching which...
Cable-driven continuum robots with hyper-redundant deformable backbones show great promise in applications, such as inspection unstructured environments, where traditional rigid discrete links and joints fail to operate. However, the motion of existing is still constrained by their homogeneous backbones, limited environments modest geometrical complexity. In this study, inspired highly elephant trunks, we presented a modular tensegrity structure preprogrammable stiffness for robots. Then...
Double C-H bond activation can enable an expeditious reaction pathway to cyclic compounds, offering efficient tool synthesize valuable molecules. However, cyclization enabled by double at one carbon atom is nearly unknown. Herein, we report a carbonylative formal cycloaddition of alkylarenes with imines via benzylic atom, allowing straightforward synthesis β-lactams from readily accessible and imines, which paves the way for developing annulation through atom.
Soft robots exhibit promising dexterity and adaptability for manipulation because of their high compliance. However, the existing soft with invariant stiffness hardly interact cluttered environments varying curvatures. In this study, inspired by maneuverability an elephant trunk, we proposed a pneumatic robot comprised actuators interference plates. By implementing plates in diverse patterns, localized our can be pre-programmed. To quantify availability regulation, constructed four typical...
Glioma relies on glycolysis to obtain energy and sustain its survival under low glucose microenvironment in vivo. The mechanisms glioma cell regulation are still unclear. Signaling mediated by Double-stranded RNA-activated protein kinase (PKR) - like ER (PERK) is one of the important pathways unfolded response (UPR) which comprehensively activated cancer cells upon hypoxic stress. Here we show that PERK significantly human tissues. silencing results decreased viability ATP/lactate production...
A capacitive sensing coating with highly linear response over a broad pressure range.
Accurate prediction of death is an unmet need in patients with acute decompensated heart failure (HF). Arachidonic acid (AA) metabolites play important role the multiple pathophysiological processes. We aimed to develop AA score accurately predict mortality HF and explore causal relationship between predictors HF.The serum was measured (discovery cohort n=419; validation n=386) by mass spectroscopy. assessed prognostic importance for 1-year using Cox regression machine learning approaches. A...
Cardiac resident MerTK
Abstract Mechanical metamaterials are rationally designed structures possessing exceptional properties that can be manufactured by 3D printing techniques. provide an unprecedented platform for energy absorption, mitigating damage caused severe localized impacts within confined areas. However, current designs always reveal deficiencies either in their absorption capacities or suitability repetitive utilization. To address such limits, a novel bistable tensegrity structure with superior...
Acute myocardial infarction (MI) and ischemic heart disease are the leading causes of failure mortality. Currently, research on MI treatment is focused angiogenic anti-inflammatory therapies. Although endothelial cells (ECs) critical for triggering inflammation angiogenesis, no approach has targeted them MI. In this study, we proposed a nonviral combined nucleic acid delivery system consisting an EC-specific polycation (CRPPR-grafted ethanolamine-modified poly(glycidyl methacrylate), CPC)...
Retinal detachment (RD) is a vision-threatening disorder of significant severity. Individuals with high myopia (HM) face 2 to 6 times higher risk developing RD compared non-myopes. The timely identification myopia-related retinal (HMRD) crucial for effective treatment and prevention additional vision impairment. Consequently, our objective was streamline validate machine-learning model based on clinical laboratory omics (clinlabomics) the early detection in HM patients.
Glioma is the most common primary brain tumor in central nervous system (CNS) with high morbidity and mortality adults. Although standardized comprehensive therapy has been adapted, prognosis of glioma patients still frustrating thus novel therapeutic strategies are urgently need. Quercetin (Quer), an important flavonoid compound found many herbs, shown to be effective some models including glioma. Recently, it reported that adequate regulation autophagy can strengthen cytotoxic effect...
Abstract Glioblastoma is the most common and aggressive primary brain tumor in adults. New drug design development still a major challenge for glioma treatment. Increasing evidence has shown that nitazoxanide, an antiprotozoal drug, novel antitumor role various tumors exhibits multiple molecular functions, especially autophagic regulation. However, whether nitazoxanide-associated autophagy antineoplastic effect remains unclear. Here, we aimed to explore underlying mechanism of nitazoxanide...
Abstract Great progress has been made to enhance the sensitivity of flexible pressure sensors recently. However, format these largely limited thin films. A highly sensitive sensor based on coatings, which can ensure uniform coverage over large area as well conformal contact with complex surfaces because flowability before solidification, rarely reported. Here, a capacitive sensing coating is demonstrated for first time. This utilizes conductive composite coatings electrodes and thermally...
miR-181a/b and miR-410 downregulation miR-155 upregulation has been shown to play important roles in the oncogenesis progression of gliomas including high-grade gliomas. However, potential role plasma miR-181a/b, diagnosis prognosis remains poorly known.We retrieved published articles from PubMed, Cochrane Central Register Controlled Trials, Web Science database obtained different sets data on microRNAs (miRNAs) expression profiling glioma highlighted most frequently dysregulated miRNAs...
Background . The efficacy of robotic‐assisted gait training (RAGT) should be considered versatilely; among which, assessment is one the most important measures; observational commonly used method in clinical practice, but it has certain limitations due to deviation subjectivity; instrumental assessments such as three‐dimensional analysis (3DGA) and surface electromyography (sEMG) can obtain data muscle activation during walking stroke patients with hemiplegia, so better evaluate...
Elephants have long been observed to grip objects with their trunk, but little is known about how they adjust strategy for different weights. In this study, we challenge a female African elephant at Zoo Atlanta lift 20-60 kg barbell weights only its trunk. We measure the trunk's shape and wrinkle geometry from frozen trunk Smithsonian. observe several strategies employed accommodate heavier weights, including accelerating less, orienting vertically, wrapping greater length. Mathematical...