Zun Li

ORCID: 0000-0003-0914-7116
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About
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Research Areas
  • Rheumatoid Arthritis Research and Therapies
  • Regional Development and Environment
  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Medical Research and Treatments
  • Winter Sports Injuries and Performance
  • Parasites and Host Interactions
  • IL-33, ST2, and ILC Pathways
  • Genomics, phytochemicals, and oxidative stress
  • Autoimmune and Inflammatory Disorders Research
  • Molecular Biology Techniques and Applications
  • Lipid metabolism and biosynthesis
  • Musculoskeletal pain and rehabilitation
  • interferon and immune responses
  • Healthcare and Venom Research
  • Renal cell carcinoma treatment
  • Liver physiology and pathology
  • Testicular diseases and treatments
  • Traditional Chinese Medicine Studies
  • Educational Reforms and Innovations
  • PI3K/AKT/mTOR signaling in cancer
  • Cancer Mechanisms and Therapy
  • Antimicrobial agents and applications
  • Orthopedic Surgery and Rehabilitation
  • Digital Imaging for Blood Diseases

Nankai University
2024

Henan University Huaihe Hospital and Huaihe Clinical Institute
2019-2023

Xuzhou Medical College
2022-2023

Xinxiang Medical University
2021-2022

Jiangsu University
2018-2022

Xinxiang University
2022

Longhua Hospital Shanghai University of Traditional Chinese Medicine
2016

Shanghai University of Traditional Chinese Medicine
2016

Binzhou Medical University
2011-2012

The utility of superb microvascular imaging (SMI) for evaluating hand joint lesions in patients with rheumatoid arthritis (RA) clinical remission is unreported. This study aimed to compare SMI and power Doppler (PDI) the evaluation these patients. Twenty-six RA were enrolled. A total 572 joints (52 wrist, 260 proximal interphalangeal, metacarpophalangeal joints) detected by PDI. semi-quantitative scale 0-3 was used detection synovial blood flow signal Inter-observer agreement assessment PDI...

10.1007/s00296-018-4112-3 article EN cc-by Rheumatology International 2018-07-30

Abstract Dynamic regulation of intestinal epithelial cell (IEC) differentiation is crucial for both homeostasis and the response to helminth infection. SIRT6 belongs NAD + -dependent deacetylases has established diverse roles in aging, metabolism disease. Here, we report that IEC Sirt6 deletion leads impaired tuft development type 2 immunity infection, thereby resulting compromised worm expulsion. Conversely, after transgenic mice exhibit enhanced remodeling process more efficient clearance....

10.1038/s41467-022-32846-4 article EN cc-by Nature Communications 2022-09-03

Testicular torsion is an acute scrotal disorder requiring immediate emergency treatment. Ischemic injury and reperfusion are important causes of oxidative stress irreversible damage after testicular torsion. Although a large number literatures have discussed the treatment torsion, there currently lack systematic exploration historical evolution construction knowledge framework.The Web Science Core Collection was searched for studies on published between 2000 2022. The basic data literature...

10.3389/fped.2023.1121677 article EN cc-by Frontiers in Pediatrics 2023-02-28

Aims: Long non-coding RNA IRAIN (lncRNA IRAIN) plays a critical role in numerous malignancies. However, the function of lncRNA renal carcinoma (RC) remains enigmatic. The purpose this study is to characterize effects on RC progression. Methods: expression pattern and vascular endothelial growth factor A (VEGFA) tissues cells was characterized by RT-qPCR Western blot analysis. roles VEGFA progression were studied gain- or loss-of-function experiments. Bioinformatics data analysis used predict...

10.3389/fonc.2020.01082 article EN cc-by Frontiers in Oncology 2020-09-02

MicroRNAs (miRNAs) are well characterized for their important roles in human cancers by influencing various aspects of malignancy. Till now, the function and mechanism miR-204, a tumor suppressor several cancers, remain unclear bladder cancer (BC). Here, we intend to explore its BC progression.qRT-PCR was applied determine miR-204 ROBO4 expression tissues cell lines. with clinicopathological features analyzed. The impacts on growth metastasis vitro were evaluated both loss-of-function...

10.2147/ott.s205023 article EN OncoTargets and Therapy 2019-10-01

Extracting features of retinal vessels from fundus images plays an essential role in computer-aided diagnosis diseases, such as diabetes, hypertension, and cerebrovascular diseases. Although a number deep learning-based methods have been used this field, the accuracy vessel segmentation remains challenging due to limited densely annotated data, inter-vessel differences, structured prediction problems, especially areas small blood optic disk. In paper, we propose ARN model with atrous block...

10.1371/journal.pone.0273318 article EN cc-by PLoS ONE 2022-08-22

Dynamic regulation of intestinal epithelial cell (IEC) proliferation and differentiation is crucial for maintaining mucosa homeostasis the response to helminth infection. O-GlcNAc transferase (OGT), an enzyme catalyzing transfer GlcNAc from donor substrate UDP-GlcNAc onto acceptor proteins, has been proposed promote remodeling expulsion by modifying activating STAT6, but whether IEC intrinsic OGT-STAT6 axis involved in anti-helminth responses not tested vivo. Here, we show that inducible...

10.3390/ijms231911137 article EN International Journal of Molecular Sciences 2022-09-22

Objective. The aim of the study is to explore relationship between degree illness in elderly patients with rheumatoid arthritis (RA) and parameters musculoskeletal ultrasound (MSUS) Oswestry Dysfunction Index (ODI) its clinical value. Methods. data 100 RA admitted our hospital from May 2016 2022 were retrospectively analyzed. divided into four groups, including remission group (DAS28 ≤ 2.6, n = 25), low activity (2.6 DAS28 3.2, middle (3.2 5.1, high (DAS > 25) according disease score-28...

10.1155/2022/4307864 article EN Evidence-based Complementary and Alternative Medicine 2022-08-02

To solve the main problems faced by medium voltage distribution network in urban core areas of China, this paper first analyzed advantages and disadvantages typical high reliability connection modes at home abroad, compared their differences power supply reliability, economy, difficulty transformation implementation, as well applicability China. Then, concept "star type" was proposed, it's structure, configuration principles, characteristics were elaborated detail. Finally, taking a grid...

10.1109/ic2ecs60824.2023.10493557 article EN 2023-12-29

Background: The objective of this study was to investigate the correlation between 7-joint ultrasound score (US7) and disease activity in patients with rheumatoid arthritis (RA). Methods: Forty-four active RA were assessed, US7 indicators such as (DAS28), factor (RF), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) analyzed. In addition, proportions points accounted for by different joint regions surfaces Results: RF, CRP, ESR significantly increased group compared control ( P...

10.4103/jmu.jmu_43_23 article EN cc-by-nc-sa Journal of Medical Ultrasound 2023-09-23
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