A5103266060- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Cardiac pacing and defibrillation studies
- Adipose Tissue and Metabolism
- Cardiomyopathy and Myosin Studies
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiac Health and Mental Health
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiac Arrhythmias and Treatments
- Blood Pressure and Hypertension Studies
- Cardiac electrophysiology and arrhythmias
- Ion channel regulation and function
- Congenital heart defects research
- Viral Infections and Immunology Research
- Congenital Heart Disease Studies
- Aortic Disease and Treatment Approaches
- Cardiovascular Disease and Adiposity
- Retinoids in leukemia and cellular processes
- Cardiac Imaging and Diagnostics
- Heart Failure Treatment and Management
- Coronary Interventions and Diagnostics
- Antibiotic Use and Resistance
- Antibiotics Pharmacokinetics and Efficacy
Fortis Escorts Heart Institute
2014-2024
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2023
Augusta University
2014-2019
University of Virginia Health System
2019
University of Cincinnati
2014
Augusta University Health
2013
Fortis Escorts Hospital
2012
Wuhan University
2011
Abstract Aims In light of recent data regarding inflammatory signalling pathways in cardiovascular disease and the recently demonstrated impact pharmacologic inhibition interleukin-1β (IL-1β) heart failure, primary aim was to assess physiologic effects cardiac resynchronization therapy (CRT) on expression systemic inflammatory, immune-modulatory, metabolic, apoptotic genes peripheral blood mononuclear cells (PBMCs) patients with failure. Methods results We used RNA sequencing (RNA-Seq)...
Introduction Current guidelines recommend continuation of dual anti-platelet therapy (DAPT) for 12 months after percutaneous coronary intervention (PCI). Recent studies have shown benefit in continuing DAPT beyond but at the risk increase bleeding. To date, there has been little data on stratifying patients to determine who can continue minimal bleeding risk. Methods: All underwent drug-eluting stent (DES) placement from January 1, 2013 September 30, 2014 were reviewed. Patients had...
To assess the effect of acute coronary syndrome (ACS) patients' education on their adherence to dual antiplatelet therapy (DAPT) and lifestyle modifications.Patients who were prescribed acetyl salicylic acid clopidogrel DAPT within 15 days having an ACS event enrolled in this study. Patients randomized into two arms: first arm received study intervention, which consisted artery disease importance sustained platelet inhibition, whereas second was control group. Both arms modifications....
Clopidogrel has been the only available antiplatelet drug used along with aspirin in patients of ACS. In recent years 2 new drugs (Prasugrel and Ticagrelor) have become available. Prasugrel dose 10 mg OD found to be more efficacious but increased risk major bleeding. For this reason it not gained widespread usage ACS undergoing PCI. There are no systematic data on use Indian population. This is a prospective, multicentric, hospital registry 1000 PCI who were administered Prasugrel. The...
Chronic kidney disease (CKD) is a major contributor to morbidity and mortality in India. CKD often coexists with heart failure (HF), diabetes, hypertension. All these comorbidities are risk factors for renal impairment. HF pathophysiologically intertwined, the deterioration of one can worsen prognosis other. There need safe pharmacological therapies that target both also useful hypertension diabetes. Neurohormonal activation achieved through sympathetic nervous system (SNS),...
Introduction: Although thousands of potentially disease-causing mutations have been identified in a handful genes, the genetic heterogeneity has led to diagnostic confusions, stemming directly from limitations our arsenal tools.Areas covered: We discuss basis cardiac ion channelopathies, gaps knowledge and how Next-generation sequencing technology (NGS) can be used bridge them, induced pluripotent stem cell (iPSC) derived-cardiomyocytes for drug discovery.Expert commentary: Univariate,...
Introduction: Myocardial noncompaction is thought to be a rare genetic disorder of myocardial morphogenesis.Case Report: We report the case 22yearold male with left ventricular noncompaction, bicuspid aortic valve and ascending dilation.We discuss basis potential etiologies that manifest in hyper trabeculated myocardium presence or absence extracardiac abnormalities.Conclusion: arise from disruption normal organogenesis during development.Many abnormalities have been associated non...
Introduction: Antimicrobial Stewardship is a coordinated program that ensures the optimal selection, dose, and duration of an antimicrobial therapy leads to best clinical outcome for treatment or prevention infection. Objectives: Objectives study are, (1) describe antibiotic stewardship implementation by critically evaluating prescribing practices; (2) design appropriate intervention subsequent implementation; (3) discern impact intervention. Methodology: An interventional cross-sectional...