A5052588802- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Intensive Care Unit Cognitive Disorders
- Family and Patient Care in Intensive Care Units
- Sepsis Diagnosis and Treatment
- Biomedical and Chemical Research
- Medical Practices and Rehabilitation
- COVID-19 diagnosis using AI
- SARS-CoV-2 and COVID-19 Research
- Immune Response and Inflammation
- Trauma and Emergency Care Studies
- Dermatological and COVID-19 studies
- Immune Cell Function and Interaction
- Electrospun Nanofibers in Biomedical Applications
- Diabetes and associated disorders
- Tissue Engineering and Regenerative Medicine
- Cancer Immunotherapy and Biomarkers
- IL-33, ST2, and ILC Pathways
- Cardiac, Anesthesia and Surgical Outcomes
- Nerve injury and regeneration
- Asthma and respiratory diseases
- Immune responses and vaccinations
- Disaster Response and Management
Otto-von-Guericke University Magdeburg
2005-2023
University Hospital Magdeburg
2021-2022
Klinikum Magdeburg
2021
University Hospital Regensburg
2020
Intensive Care Resources are heavily utilized during the COVID-19 pandemic. However, risk stratification and prediction of SARS-CoV-2 patient clinical outcomes upon ICU admission remain inadequate. This study aimed to develop a machine learning model, based on retrospective & prospective data, stratify predict survival outcomes.A Germany-wide electronic registry was established pseudonymously collect admission, therapeutic discharge information patients retrospectively prospectively. Machine...
Microbial infections early in life are challenging for the unexperienced immune system. The SARS-CoV-2 pandemic again has highlighted that neonatal, infant, child, and adult T-helper(Th)-cells respond differently to infections, requires further understanding. This study investigates anti-bacterial T-cell responses against Staphylococcus aureus aureus, epidermidis Bifidobacterium longum infantis stages of adults shows age pathogen-dependent mechanisms. Beside activation-induced clustering,...
Defects of peripheral nerves are bridged with autologous nerve grafts. Tissue-engineered grafts offer a laboratory-based alternative to overcome limited donor availability. Our objective was evaluate whether graft made from acellular muscle enriched cultivated Schwann cells can bridge extra large gaps where conventional conduits usually fail. well-established rat sciatic model used an increased gap length 50 mm. The consisted freeze–thawed or chemically extracted homologous rectus muscles...
After recovery, mild and severe COVID-19 diseases are associated with long-term effects on the host immune system, such as prolonged T-cell activation or accumulation of autoantibodies. In this study, we show that SARS-CoV-2 infections, but not spike mRNA vaccinations, cause durable atopic risk factors a systemic Th2- Th17-type environment well B cells responsive IgE against aeroallergens from house dust mite mold. At an average 100 days post anti-mold responses were low IL-13 levels...
Abstract Background. Intensive Care Resources are heavily utilized during the COVID-19 pandemic. However, risk stratification and prediction of SARS-CoV-2 patient clinical outcomes upon ICU admission remain inadequate. This study aimed to develop a machine learning model, based on retrospective & prospective data, stratify predict survival outcomes. Methods. A Germany-wide electronic registry was established pseudonymously collect admission, therapeutic discharge information patients...