Susan E. Van Aken

ORCID: 0000-0003-0970-498X
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About
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Research Areas
  • vaccines and immunoinformatics approaches
  • Geochemistry and Elemental Analysis
  • Neonatal and Maternal Infections
  • Plant Pathogenic Bacteria Studies
  • Bacteriophages and microbial interactions
  • Phytoplasmas and Hemiptera pathogens
  • Radioactive element chemistry and processing
  • Entomopathogenic Microorganisms in Pest Control
  • Insect symbiosis and bacterial influences
  • Malaria Research and Control
  • Invertebrate Immune Response Mechanisms
  • Plant-Microbe Interactions and Immunity
  • Genomics and Phylogenetic Studies
  • Streptococcal Infections and Treatments
  • Brucella: diagnosis, epidemiology, treatment
  • Legume Nitrogen Fixing Symbiosis
  • Pneumonia and Respiratory Infections
  • Microbial Fuel Cells and Bioremediation

J. Craig Venter Institute
2002-2006

University of Massachusetts Amherst
2003

United States Department of Agriculture
2003

University of Nebraska–Lincoln
2003

Cornell University
2003

Brigham and Women's Hospital
2002

Harvard University
2002

Johns Hopkins University
2002

Walter Reed Army Institute of Research
2002

Virginia–Maryland College of Veterinary Medicine
2002

We report the complete genome sequence of model bacterial pathogen Pseudomonas syringae pathovar tomato DC3000 (DC3000), which is pathogenic on and Arabidopsis thaliana . The (6.5 megabases) contains a circular chromosome two plasmids, collectively encode 5,763 ORFs. identified 298 established putative virulence genes, including several clusters genes encoding 31 confirmed 19 predicted type III secretion system effector proteins. Many were members paralogous families also proximal to mobile...

10.1073/pnas.1731982100 article EN Proceedings of the National Academy of Sciences 2003-08-19

Species of malaria parasite that infect rodents have long been used as models for disease research. Here we report the whole-genome shotgun sequence one species, Plasmodium yoelii yoelii, and comparative studies with genome human falciparum clone 3D7. A synteny map 2,212 P. y. contiguous DNA sequences (contigs) aligned to 14 chromosomes reveals marked conservation gene within body each chromosome. Of about 5,300 genes, more than 3,300 orthologues predominantly metabolic function were...

10.1038/nature01099 article EN cc-by-nc-sa Nature 2002-10-03

The complete genome sequence of Geobacter sulfurreducens, a delta-proteobacterium, reveals unsuspected capabilities, including evidence aerobic metabolism, one-carbon and complex carbon motility, chemotactic behavior. These characteristics, coupled with the possession many two-component sensors c-type cytochromes, reveal an ability to create alternative, redundant, electron transport networks offer insights into process metal ion reduction in subsurface environments. As well as playing roles...

10.1126/science.1088727 article EN Science 2003-12-11

The 2,160,267 bp genome sequence of Streptococcus agalactiae , the leading cause bacterial sepsis, pneumonia, and meningitis in neonates U.S. Europe, is predicted to encode 2,175 genes. Genome comparisons among S. pneumoniae pyogenes other completely sequenced genomes identified genes specific streptococci . These silico analyses, combined with comparative hybridization experiments between serotype V strain 2603 V/R 19 strains from several serotypes using whole-genome microarrays, revealed...

10.1073/pnas.182380799 article EN Proceedings of the National Academy of Sciences 2002-08-28

The 3.31-Mb genome sequence of the intracellular pathogen and potential bioterrorism agent, Brucella suis , was determined. Comparison B. with melitensis has defined a finite set differences that could be responsible for in virulence host preference between these organisms, indicates phage have played significant role their divergence. Analysis reveals transport metabolic capabilities akin to soil/plant-associated bacteria. Extensive gene synteny chromosome 1 plant symbiont Mesorhizobium...

10.1073/pnas.192319099 article EN Proceedings of the National Academy of Sciences 2002-09-23

Mutualistic intracellular symbiosis between bacteria and insects is a widespread phenomenon that has contributed to the global success of insects. The symbionts, by provisioning nutrients lacking from diets, allow various occupy or dominate ecological niches might otherwise be unavailable. One such insect glassy-winged sharpshooter (Homalodisca coagulata), which feeds on xylem fluid, diet exceptionally poor in organic nutrients. Phylogenetic studies based rRNA have shown two types bacterial...

10.1371/journal.pbio.0040188 article EN cc-by PLoS Biology 2006-05-26

This article describes the features of ultrastructure lungs vertebrates belonging to different biotopes.Due habitat in fine structure lung tendon spines (amphibians, reptiles, small mammals), significant differences were detected by electron and scanning microscopy.In study light amphibians living various biotopes, presence "living" formations "mixed" cells was observed.In addition, type I pneumocytes predominate, II is rarely common.Amphibians (tailed frog) steppe zone actively excrete...

10.32014/2019.2519-1629.28 article EN SERIES OF BIOLOGICAL AND MEDICAL 2019-06-15
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