A5087092731- Neural and Behavioral Psychology Studies
- Functional Brain Connectivity Studies
- Neurotransmitter Receptor Influence on Behavior
- Neural dynamics and brain function
- Memory and Neural Mechanisms
- Mental Health Research Topics
- Attention Deficit Hyperactivity Disorder
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- EEG and Brain-Computer Interfaces
- Substance Abuse Treatment and Outcomes
- Behavioral Health and Interventions
- Visual perception and processing mechanisms
- Multiple Sclerosis Research Studies
- Schizophrenia research and treatment
- Spatial Neglect and Hemispheric Dysfunction
- Decision-Making and Behavioral Economics
- Cognitive Abilities and Testing
- Cardiac Health and Mental Health
- Dementia and Cognitive Impairment Research
- Psychology of Moral and Emotional Judgment
- Smoking Behavior and Cessation
- Cognitive Functions and Memory
- Advanced Neuroimaging Techniques and Applications
- Alcohol Consumption and Health Effects
- Family Support in Illness
The University of Melbourne
2016-2025
Australian Psychological Society
2014-2023
Peter MacCallum Cancer Centre
2019-2020
Swinburne University of Technology
2019-2020
Monash Health
2019-2020
Monash University
2020
University of Oregon
2018
Orygen
2018
University of Vermont
2018
Icahn School of Medicine at Mount Sinai
2018
Using a GO-NOGO response inhibition task in which working memory (WM) demands can be varied, we demonstrate that the compromised abilities of cocaine users to exert control over strong prepotent urges are associated with reduced activity anterior cingulate and right prefrontal cortices, two regions thought critical for implementing cognitive control. Furthermore, unlike drug-naive controls, opposite pattern, showed an over-reliance on left cerebellum, compensatory pattern previously seen...
Abstract Error‐processing research has demonstrated that the brain uses a specialized neural network to detect errors during task performance but regions necessary for conscious awareness of an error are poorly understood. In present study we show two well‐known error‐related event‐related potential (ERP) components, negativity (ERN) and positivity (Pe) have differential relationship with manual response inhibition optimized examine awareness. While ERN was unaffected by participants'...
Although lower brain volume has been routinely observed in individuals with substance dependence compared nondependent control subjects, the regions exhibiting have not consistent across studies. In addition, it is clear whether a common set of are involved regardless used or some effects specific. Resolution these issues may contribute to identification clinically relevant imaging biomarkers. Using pooled data from 14 countries, authors sought identify general and substance-specific...
The US National Institutes of Mental Health Research Domain Criteria (RDoC) seek to stimulate research into biologically validated neuropsychological dimensions across mental illness symptoms and diagnoses. RDoC framework comprises 39 functional constructs designed be revised refined, with the overall goal improving diagnostic validity treatments. This study aimed reach a consensus among experts in addiction field on 'primary' most relevant substance behavioural addictions.Forty-four were...
Abstract Using event‐related fMRI, this study investigated the neural dynamics of response inhibition under fluctuating task demands. Fourteen participants performed a GO/NOGO requiring prepotent motor to NOGO events that occurred as part either Fast or Slow presentation stream GO stimuli. We compared functional activations associated with correct withholds (Stops) required during stimuli Stops stream. A predominantly right hemispheric network was activated across conditions, consistent...
The central executive component of working memory has been argued to play an important role in the performance span tasks, particularly backward span. Age-related decline function also reported, and yet there have inconsistent findings indicate that with increasing age, discrepancy between forward increases. A secondary analysis Wechsler Memory Scale–Third Edition standardization sample ( N = 1030) was performed investigate this relationship. It hypothesized on basis past research indicating...
Compromised ability to exert control over drug urges and drug-seeking behaviour is a characteristic of addiction. One specific cognitive function, impulse control, has been shown be risk factor for the development substance problems linked in animal models increased administration relapse. We present evidence direct effect cocaine on neurobiology underlying control. In laboratory test motor response inhibition, an intravenous improved task performance 13 users. This improvement was...
Abstract We assessed the inter‐rater reliability of 100‐point International Cooperative Ataxia Rating Scale (ICARS). Three neurologists independently rated videotaped ICARS examinations 22 subjects with genetically determined ataxias (spinocerebellar ataxia [SCA] Type 1 in 11; SCA 2 1; Friedreich's 10) and 4 controls. Scores on live assessment had ranged from 0 to 7 for controls 11 74 ataxic (clinically very mildly affected wheelchair‐bound). Inter‐rater correlation was high total score...
Abstract The present study investigated the relationships between attention and other preparatory processes prior to a response inhibition task involved in itself. To achieve this, mixed fMRI design was employed identify functional areas activated during both decision events block of trials following visual cue introduced 2 7 sec (cue period). Preparing for successful performance produced increases activation period itself frontoparietal cortical network. Furthermore, preparation decreases...