A5091497673- Epilepsy research and treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Neuroscience and Neuropharmacology Research
- Pharmacological Effects and Toxicity Studies
- Diet and metabolism studies
- Traumatic Brain Injury Research
- Neuroinflammation and Neurodegeneration Mechanisms
- Cardiac Arrest and Resuscitation
- Gut microbiota and health
- Advanced Glycation End Products research
- Tryptophan and brain disorders
- Gastrointestinal motility and disorders
- S100 Proteins and Annexins
- Metabolism and Genetic Disorders
- Neonatal and fetal brain pathology
- Alzheimer's disease research and treatments
- Ion channel regulation and function
- Cardiovascular Syncope and Autonomic Disorders
- Long-Term Effects of COVID-19
- Neonatal Respiratory Health Research
- Autophagy in Disease and Therapy
- EEG and Brain-Computer Interfaces
- Pregnancy and Medication Impact
- Heme Oxygenase-1 and Carbon Monoxide
- Medicinal Plants and Neuroprotection
Monash University Malaysia
2014-2025
The University of Adelaide
2016-2023
Huntington's disease (HD), a neurodegenerative disease, normally starts in the prime of adult life, followed by gradual occurrence psychiatric disturbances, cognitive and motor dysfunction. The daily performances life quality HD patients have been severely interfered these clinical signs symptoms until last stage neuronal cell death. To best our knowledge, no treatment is available to completely mitigate progression HD. Mangiferin, naturally occurring potent glucoxilxanthone, mainly isolated...
Abstract Objective Posttraumatic epilepsy (PTE) and cognitive impairment are severe complications following traumatic brain injury (TBI). Neuroinflammation likely contributes, but the role of specific inflammatory mediators requires clarification. High‐mobility group box 1 (HMGB1) is an cytokine released after that may be involved. This prospective longitudinal study investigated whether serum HMGB1 levels associated with PTE development decline over 12 months post‐TBI. Methods Serum samples...
Traumatic brain injury (TBI) is associated with an increased risk of developing Parkinson’s disease (PD), though the exact mechanisms remain unclear. TBI triggers acute neuroinflammation and catecholamine dysfunction post-injury, both implicated in PD pathophysiology. The long-term impact on these pathways following TBI, however, remains uncertain. In this study, male Sprague-Dawley rats underwent sham surgery or Marmarou’s acceleration model to induce varying severities: single mild (mTBI),...
Epilepsy is characterized by an imbalance in neurotransmitter activity; increased excitatory to inhibitory activity. Acetylcholine (ACh), serotonin, and norepinephrine (NE) may modulate neural activity via several mechanisms, mainly through its receptors/transporter alterations the extracellular potassium (K+) concentration K+ ion channels. Seizures disrupt regulation of inwardly rectifying (Kir) channels alter receptor/transporter However, there are limited data present on immunoreactivity...