A5076873364- Epilepsy research and treatment
- Pharmacological Effects and Toxicity Studies
- Acute Ischemic Stroke Management
- Infectious Encephalopathies and Encephalitis
- Peripheral Neuropathies and Disorders
- Stroke Rehabilitation and Recovery
- Parkinson's Disease Mechanisms and Treatments
- Long-Term Effects of COVID-19
- Neuroscience and Neuropharmacology Research
- Restless Legs Syndrome Research
- Myasthenia Gravis and Thymoma
- Traumatic Brain Injury and Neurovascular Disturbances
- Venous Thromboembolism Diagnosis and Management
- Autoimmune Neurological Disorders and Treatments
- Multiple Sclerosis Research Studies
- Neurological and metabolic disorders
- Cerebrovascular and Carotid Artery Diseases
- Genetics and Neurodevelopmental Disorders
- Parkinson's Disease and Spinal Disorders
- Electrolyte and hormonal disorders
- SARS-CoV-2 and COVID-19 Research
- RNA regulation and disease
- Helicobacter pylori-related gastroenterology studies
- Neurological disorders and treatments
- COVID-19 Clinical Research Studies
National University of Malaysia
2011-2025
University Kebangsaan Malaysia Medical Centre
2015-2025
Hospital Kuala Lumpur
2023-2025
National Environment Agency
2024
Shantou University
2023
Second Affiliated Hospital of Shantou University Medical College
2023
Chenzhou First People's Hospital
2017-2020
Xiangnan University
2020
Serdang Hospital
2020
Lieber Institute for Brain Development
2017
Patients with mild or moderate chronic obstructive pulmonary disease (COPD) rarely receive medications, because they have few symptoms. We hypothesized that long-term use of tiotropium would improve lung function and ameliorate the decline in patients COPD.
Background Previous studies have demonstrated a higher prevalence of Helicobacter pylori (H. pylori) infection in patients with Parkinson's disease (PD) compared to controls. H. affects levodopa absorption and its eradication significantly improves clinical response levodopa. Here, we studied the effects among our PD patients. Methods A prospective study involving idiopathic on therapy. 13C-urea breath test (UBT) was used detect pylori. UBT-positive were given standard therapy followed up at...
Abstract Objective Posttraumatic epilepsy (PTE) and cognitive impairment are severe complications following traumatic brain injury (TBI). Neuroinflammation likely contributes, but the role of specific inflammatory mediators requires clarification. High‐mobility group box 1 (HMGB1) is an cytokine released after that may be involved. This prospective longitudinal study investigated whether serum HMGB1 levels associated with PTE development decline over 12 months post‐TBI. Methods Serum samples...
Background: Antiseizure medication (ASM) therapy has been the mainstay of pharmacological management epilepsy. The goal treatment includes achieving good seizure outcomes while minimising risk adverse effects (AE). In developing countries, therapeutic remain suboptimal. This study aimed to determine prevalence ASM and its associated factors. Methods: was conducted in a public, hospital-based specialist clinic. People with epilepsy (PWE) who were prescribed at least one screened for...
Objective To systematically evaluate the therapeutic effect of intravenous thrombolysis after acute ischaemic stroke caused by workplace violence, and to provide reference for healthcare professionals optimise care model implement precise intervention. Methods Computer searches Cochrane Library, PubMed, Embase, CINAHL, Web Science other databases were used search qualitative studies on treatment experiencing violence from time database construction May 2023. The quality literature was...
Posttraumatic epilepsy (PTE) significantly impacts morbidity and mortality, yet local PTE data remain scarce. In addition, there is a lack of evidence on cognitive comorbidity in individuals with the literature. We sought to identify potential predictors evaluate patients PTE.
Stroke is a typical medical emergency that carries significant disability and morbidity. The diagnosis of stroke relies predominantly on the use neuroimaging. Accurate pertinent for management decisions thrombolysis and/or thrombectomy. Early identification using electroencephalogram (EEG) in clinical assessment has been underutilized. This study was conducted to determine relevance EEG its predictors with features.A cross-sectional carried out where routine performed 206 consecutive acute...
Background . The nonmotor symptoms are important determinants of health and quality life in Parkinson’s disease but not well recognized addressed clinical practice. This study was conducted to determine the prevalence their impact on patients with disease. Methods a cross-sectional among idiopathic Exclusion criteria were Mini Mental State Examination score <21/30. Prevalence determined using NMSQuest. severity assessed validated disease-specific questionnaires (PDQ-39 NMSS). Results A...
Abstract Background Dengue is a common illness in the tropics. Equally are neurological complications that stem from dengue infection. However, to date, parkinsonism following has not been reported medical literature. Case presentation A previously well 18-year old man developed parkinsonism, addition other symptoms serologically confirmed fever. Alternative etiologies were excluded by way of imaging and blood investigations. Conclusions The authors detail first case complicating Keeping...
<i >Introduction</i>. Restless legs syndrome has been shown to negatively impact the quality of life patients. Studies have an association between restless and Parkinson’s disease. We attempted investigate prevalence in disease patients identify associated risk factors. >Method</i>. This was a cross-sectional study among with idiopathic Exclusion criterion Mini Mental State Examination score less than 21/30. The International Legs Syndrome Study Group used syndrome. >Results</i>. A...
To investigate the significance of proton magnetic resonance spectroscopy (1H-MRS) and glutamate chemical exchange saturation transfer (Glu-CEST) techniques in assessing condition prognosis acute bilirubin encephalopathy patients to understand mechanism nerve injury this disease.From September 2019 February 2021, 31 neonates with 16 healthy were enrolled study. All quantitative results 1H-MRS, Glu-CEST, conventional imaging (MRI) all analyzed. The associations between statistically...
ABSTRACT Over‐expression of P‐glycoprotein, encoded by the ABCB1 gene, is proposed to be involved in resistance antiepileptic drugs about 30% patients with epilepsy. Here, we investigated possible association between polymorphisms and sodium valproate (VPA) treatment Malaysian epilepsy patients. Genotypes were assessed 249 drug‐resistant 256 drug‐responsive for C1236T, G2677T/A, C 5T gene. No genotypes, alleles, or haplotypes associated response VPA either overall group Chinese, Indian,...