Shuyun Chen

ORCID: 0000-0003-4166-4535
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About
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Research Areas
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Respiratory Support and Mechanisms
  • Asthma and respiratory diseases
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Muscle Physiology and Disorders
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Tracheal and airway disorders
  • Hereditary Neurological Disorders
  • Cardiac Arrest and Resuscitation
  • Diagnosis and treatment of tuberculosis
  • Sexual Differentiation and Disorders
  • Ovarian function and disorders
  • Venous Thromboembolism Diagnosis and Management
  • Infectious Diseases and Tuberculosis
  • Inflammatory Biomarkers in Disease Prognosis
  • Esophageal and GI Pathology
  • Esophageal Cancer Research and Treatment
  • Bone fractures and treatments
  • Mycobacterium research and diagnosis
  • Cardiomyopathy and Myosin Studies
  • Hormonal and reproductive studies
  • Reliability and Agreement in Measurement

First Affiliated Hospital of Guangzhou Medical University
2021-2024

State Key Laboratory of Respiratory Disease
2017-2024

Guangzhou Medical University
2014-2024

Nanchang University
2016-2022

Xian Yang Central Hospital
2022

Karolinska Institutet
2022

First Affiliated Hospital of Nanchang University
2016-2021

Shanxi Provincial Children's Hospital
2016-2020

Weatherford College
2020

Ethica (Canada)
2020

Mutations in the LDB3 gene have been identified patients with Z‐disc‐associated, alternatively spliced, PDZ motif‐containing protein (ZASP)‐related myofibrillar myopathy (ZASP‐MFM) characterized by late‐onset distal signs of cardiomyopathy and neuropathy. We describe an autosomal dominant inherited pedigree ZASP‐MFM that is line typical phenotype without neuropathy, while mild asymmetrical muscle atrophy can be observed some affected members. Muscle MRI revealed considerable fatty...

10.1111/neup.12328 article EN Neuropathology 2016-08-21

Introduction Owing to the high and increasing morbidity mortality, chronic obstructive pulmonary disease (COPD) has become a major public health problem worldwide. Although majority of patients with COPD are in early stages, little attention been paid them, particular regarding intervention. Tiotropium bromide can significantly relieve symptoms reduce incidence acute exacerbations COPD. Therefore, we hypothesise that therapy tiotropium will benefit early-stage disease. Method/analysis A...

10.1136/bmjopen-2013-003991 article EN cc-by-nc BMJ Open 2014-02-01

Purpose: The use of simple and affordable screening tools for chronic obstructive pulmonary disease (COPD) is limited. We aimed to assess the validity a handheld expiratory flowmeter (Vitalograph Ltd., COPD-6 ® , Ireland) COPD in Chinese primary care settings. Methods: In our cross-sectional study, subjects were randomly selected eight Tests with conventional spirometry sequentially performed on all participants. correlation between was determined. Validity determined by area under receiver...

10.2147/copd.s312190 article EN cc-by-nc International Journal of COPD 2021-07-01

Abstract The presence of left ventricular hypertrophy has been confirmed to be an independent risk factor for stroke and death in patients with atrial fibrillation. This retrospective study aimed evaluate the potential factors A series consecutive diagnosed fibrillation between June 2018 December 2019 were included. patients’ clinical data analyzed. cut-off values, sensitivity specificity calculated using a receiver operating characteristic curve. Among 87 fibrillation, 39 48 without...

10.1097/md.0000000000022119 article EN Medicine 2020-09-10

Aromatase inhibitors (AIs), such as anastrozole, have shown effectiveness in treating oligoasthenozoospermia due to abnormal testosterone estradiol (T/E2) ratio (T/E2 <10). However, its efficacy subfertile men without T/E2 >10) remained unevaluated. This retrospective study aimed investigate whether patients with >10 could also benefit from anastrozole treatment.One hundred and five treated 1 mg daily were included, which 62 had a of <10, 43 this >10. Semen parameters sex hormone levels...

10.21037/tau-22-95 article EN Translational Andrology and Urology 2022-09-01

Objective To evaluate the incidence of postoperative complications for thoracoscopy esophageal atresia (EA) through a literature review. Methods A total 407 domestic and foreign cases thoracoscope were retrieved last decade. The relevant databases Wanfang, China Hownet, Chinese Medical Knowledge Network PubMed. Based upon inclusion exclusion criteria, all records collected. Meta R 3.1.2 software package was utilized. And Freeman Tukey double arc sine transformation method employed...

10.3760/cma.j.issn.0253-3006.2016.10.004 article EN Zhonghua xiaoerwaike zazhi 2016-10-15

Objective To observe the effect of smoking status on lung function in Chinese people >40 years age by a 2-year longitudinal follow-up. Methods This study prospectively investigated 2 682 cases pulmonary ventilation function, status, regularity residents drug combination and gender, age, height, weight other information, observation time for two years, 290 (85.4%) complete follow-up study. Results Of people, 1 197 (52.3%) are never-smokers, 467 (20.4%) ex-smokers, 626 (27.3%)...

10.3760/cma.j.issn.1673-436x.2017.14.005 article EN Chinese Journal of Asthma 2017-07-20

<title>Abstract</title> <bold>Background:</bold>To investigate the results and analyze diagnostic value of combined application EBUS-TBNA T-SPOT in patients with granuloma mediastinal-hilar lymph nodes.<bold>Methods:</bold>Patients who underwent pathologically confirmed as node granulomatous lesions from January 2020 to May 2021 were retrospectively recruited. The baseline clinical characteristics, tuberculosis T cell spot test, pathological imaging these subjects collected. common disease...

10.21203/rs.3.rs-2253340/v1 preprint EN cc-by Research Square (Research Square) 2022-12-01
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