A5100692128- Diabetic Foot Ulcer Assessment and Management
- Wound Healing and Treatments
- Pressure Ulcer Prevention and Management
- Biochemical effects in animals
- Orthopedic Infections and Treatments
- Peripheral Artery Disease Management
- Pancreatic function and diabetes
- Pharmacological Effects of Natural Compounds
- Medical and Biological Ozone Research
- Antimicrobial Resistance in Staphylococcus
- Pharmaceutical studies and practices
- Galectins and Cancer Biology
- Bacterial biofilms and quorum sensing
- Angiogenesis and VEGF in Cancer
- Endoplasmic Reticulum Stress and Disease
- Hematological disorders and diagnostics
- 3D Printing in Biomedical Research
- Protease and Inhibitor Mechanisms
- Pregnancy and preeclampsia studies
- Asthma and respiratory diseases
- Free Radicals and Antioxidants
- Osteomyelitis and Bone Disorders Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Autophagy in Disease and Therapy
- Forensic Entomology and Diptera Studies
Capital Medical University
2009-2025
Beijing Shijitan Hospital
2018-2025
Nanjing University of Chinese Medicine
2025
Capital University
2009-2024
Beijing Obstetrics and Gynecology Hospital
2021
Ningbo University
2020
Harbin Medical University
2016-2020
Beijing Hospital of Traditional Chinese Medicine
2020
Beijing Luhe Hospital Affiliated to Capital Medical University
2014
Constipation, mainly characterized by the difficulty in defecation, is a clinical symptom caused variety of factors. It can be manifested as normal or slow colonic transport abnormalities, which occur alone concurrently with defecation disorders. As there not uniform definition and assessment standard, no clear plan could used for treatment constipation. Although rhubarb, traditional Chinese medicine, plays therapeutic role diseases involving constipation symptoms, detailed mechanism it...
<title>Abstract</title> <italic>Background</italic>. Diabetic foot (DF) is a destructive complication of diabetes,which has high amputation rate and causes great social burden. With the development artificial intelligence, there an urgent need for accurate prediction method prognosis chronic diseases. <italic>Methods</italic>. This retrospective study collected data 149 patients with DF from January 2019 to December 2022. The was divided into test set training by 5-fold cross-validation....
Coexistence of depression and diabetes has a negative impact on both lifestyle quality life. Astaxanthin (AST) been demonstrated to improve the glucose metabolism antidepressant-like effect, but whether AST potential benefits for preventing in is still unknown. The aim this study was investigate preventive therapeutic effects or depressive-like behaviors diabetic rat model generated by feeding with high-fat diet 10 weeks followed injection 25 mg/kg STZ. Preventive treatment given at doses...
Osteomyelitis is bacterial infection of bone, commonly caused by Staphylococcus aureus. This work aims to study the potential azithromycin and kaempferol against chronic osteomyelitis induced azithromycin-resistant aureus (ARSA). It was noticed that rats tolerated treatments with no diarrhoea or weight loss; also, deaths were observed in rats. The treatment alone failed inhibit growth also had effect on condition although decreased levels interleukin-6 (IL-6) tumour necrosis factor-α...
Kindlin-2 is involved in activating the integrin signaling pathway which plays an important role regulating cancer cell invasion. However, of kindlin-2 may vary among types. The aim this study was to explore possible association between and clear renal carcinoma (ccRCC), its potential prognosis ccRCC. Immunohistochemistry assays were used examine expression levels tissues obtained from 336 patients with correlation pathologic variables then analyzed. In addition, survival time analyzed by...
Abstract Honey is thought to act against microbes and regulates microbiota balance, this mainly attributed the enzymatic production of hydrogen peroxide, high osmolarity, nonperoxidase factors, for example, lysozyme botanical sources nectar, while effect honey's probiotic recently considered. The study honey as source beneficial understudied. purpose was screen microorganisms in with antagonistic property important pathogens mechanism antimicrobial activity thus play a role probiotics....
Background: Osteomyelitis of the diabetic foot is a costly health problem worldwide. Early and accurate diagnosis disease in patients with infections needed urgently will have an important role management. Methods: This was case-control study subjects ulcers admitted to Beijing Shijitan Hospital from September 2015 April 2018. We compared differences atherogenic index plasma (AIP) or without osteomyelitis. Results: The mean AIP 165 osteomyelitis 0.23 ± 0.24, which significantly higher than...
<title>Abstract</title> <italic>Background</italic>. Diabetic foot (DF) disease, which includes ulcers, infections and gangrene of the feet, is one leading causes disability worldwide. Due to high rate expensive treatment cost diabetic foot, doctors patients all hope forecast prognosis in time give early intervention. With development artificial intelligence technology, more methods are used diagnosis prediction chronic diseases. Machine learning, a type intelligence, has excellent...
Diabetic foot is one of the serious complications diabetic patients. It caused by diabetes combined with different degrees lower extremity vascular lesions and neuropathy, wound can not heal for a long time. The results cause bone marrow infection, destruction, have high disability death rate. At present, there are various treatment methods chronic wound. On basis internal medicine controlling blood sugar, anti lowering lipid, improving microcirculation nourishment nerve, surgical method...
Background: High purity oxygen therapy has good clinical efficacy in the treatment of diabetic foot (DF), but its mechanism promoting wound healing been unclear. Methods: Patients with DF were randomly divided into an experimental group and a control group. The was given local (LOT) by micro-oxygen instrument, which administered uninterrupted >95% pure for 24 h at flow rate 3 mL/h. Six skin samples from before after underwent RNA sequencing (RNA-seq), differentially expressed genes (DEGs)...
Diabetic foot is a serious complication in patients with diabetes. It caused by diabetes combined lower extremity vascular lesions and neuropathy so that wound does not heal for long time. In severe cases, it may lead to bone marrow infection destruction, high disability fatality rate. This report describes the case of patient diabetic hallux gangrene disease, which was treated surgical debridement, ozone therapy, interventional surgery. Using this treatment, can be cured better faster,...
The 8th World International Symposium on the Diabetic Foot (ISDF) Conference which was sponsored by Working Group (IWGDF) held in Hague between May 22nd and 25th, 2019. conference issued 2019 IWGDF guidelines prevention management of diabetic foot disease. update to 2015 edition involves following 6 chapters: ulcers patients with diabetes; offloading diagnosis, prognosis, peripheral arterial disease a ulcer diagnosis treatment infection interventions enhance healing classification ulcers....
Trisomy 21 is a common birth defect in humans. Screening for trisomy one of the most important tasks routine prenatal care and robust noninvasive diagnostics are needed clinical practice. Urinary proteomics offers new research platform innovation this context. We report here biomarker candidates using urinary profiling. Specifically, we used liquid chromatography-tandem mass spectrometry (LC-MS/MS) to analyze proteomes urine samples from 19 pregnant women (aged 28-44 years) carrying fetuses...
Vascular fibrosis is a widespread pathologic condition that arises during vascular remodeling in cardiovascular dysfunctions. According to previous studies, characterized by endothelial matrix deposition and wall thickening. The RAAS TGF-β/Smad signaling pathways have been frequently highlighted. It is, however, far from explicit terms of understanding the cause progression fibrosis. In this review, we collected categorized large number molecules which influence fibrosing process, order...
To investigate the clinical effect of extracorporeal circulation compression perfusion (ECCP) in treatment diabetic foot.We retrospectively evaluated 89 patients with foot admitted from January 2017 to April 2019. The were grouped according whether they received ECCP treatment; experimental group: 27 patients, controls: 62 patients. After applying inclusion criteria and exclusion criteria, there 21 group control group. Foot microcirculation was by measuring percutaneous oxygen partial...