A5100346250- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Cancer Treatment and Pharmacology
- Cardiovascular Health and Disease Prevention
- Cancer Mechanisms and Therapy
- Esophageal Cancer Research and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Musculoskeletal pain and rehabilitation
- Cardiovascular Disease and Adiposity
- Exercise and Physiological Responses
- Acupuncture Treatment Research Studies
- Alcohol Consumption and Health Effects
- Peptidase Inhibition and Analysis
- Curcumin's Biomedical Applications
- Pediatric Urology and Nephrology Studies
- Traditional Chinese Medicine Analysis
- Traumatic Brain Injury and Neurovascular Disturbances
- Trauma Management and Diagnosis
- Pharmacological Effects of Natural Compounds
- Nanoparticle-Based Drug Delivery
- Renal and Vascular Pathologies
- Cancer, Hypoxia, and Metabolism
Sun Yat-sen University
2024
Sun Yat-sen Memorial Hospital
2024
Linyi People's Hospital
2014-2024
Xi'an Chest Hospital
2023
Fujian Medical University
2023
Nanjing University of Chinese Medicine
2021
Xuzhou Medical College
2015
Shandong University
2014
Wenzhou Medical University
2014
Central post-stroke pain (CPSP) is an intractable and disabling central neuropathic that severely affects patients' lives, well-being, socialization abilities. However, CPSP has been poorly studied mechanistically its treatment remains challenging. Here, we used a rat model of induced by thalamic hemorrhage to investigate underlying mechanisms the effect stellate ganglion block (SGB) on emotional comorbidities.Thalamic was produced injecting collagenase IV into ventral-posterolateral nucleus...
Purpose: To analyze the efficacy of epalrestat combined with Sulodexide in treatment diabetic peripheral neuropathy type 2 diabetes. Methods: A total 140 patients neuropathy, who were treated at Zhanjiang Central People's Hospital between February 2022 and 2023, selected as subjects. They randomly divided into two groups using a computer- generated random number table. The control group (n = 70) received treatment, while study was combination Sulodexide11. Efficacy, nerve conduction...
Prostate cancer (PCa) is the second most-frequently diagnosed in men. Cabazitaxel was approved for treatment of patients with hormone-refractory metastatic prostate previously treated a docetaxel-containing regimen.In this study, bombesin (BN), ligand reported to specifically target GRP overexpressing tumor, applied construction lipid-polymer hybrid nanoparticles (LPNs), and used targeted delivery cabazitaxel (CAB) cancer.BN-polyethylene glycol-1,2-Distearoyl-sn-glycero-3-phosphoethanolamine...
Although duloxetine has been approved for clinical therapy diabetic peripheral neuropathic pain, the exact mechanism underlying anti-allodynic effects in rat models of diabetes mellitus remains obscure. We attempted to identify whether exerts via inhibition TLR4-Myd88-dependent pathway pain (DNP) rats.An animal model type 1 was induced by intraperitoneal streptozotocin 108 rats randomized into four groups: control, DNP, solvent control + and DNP duloxetine. The establishment validated,...
This study aimed to characterize the systemic lipid profile of patients with asymptomatic hyperuricemia (HUA) and gout using lipidomics, find potential underlying pathological mechanisms therefrom.Sera were collected from Affiliated Hospital Nanjing University Chinese Medicine as centre 1 (discovery internal validation sets) Suzhou Traditional 2 (external set), including 88 normal subjects, 157 HUA 183 patients. Lipidomics was performed by ultra high performance liquid chromatography plus...
Abstract Introduction Chronic complications of diabetes have become the leading cause death in elderly patients with diabetes. Carotid atherosclerosis, one major complications, was evaluated and effects atorvastatin on carotid atherosclerosis very type 2 were observed. Materials Methods Patients divided into three groups: (i) disease course <5 years; (ii) 5–10 (iii) >10 years, evaluated. The treated statins, effect Results intima‐media thickness values, plaque instability levels...
Resectable lung adenocarcinoma is dominated by peripheral distribution, and surgical resection the main treatment protocol. However, high recurrence rate remains after surgery. Lung with epidermal growth factor receptor (EGFR) mutation has strong invasion ability, but effects of this on local in early have been rarely studied. This study aimed to assess EGFR resectable adenocarcinoma. A retrospective analysis 103 patients clinically diagnosed was included. They underwent preoperative...
Currently, there is no consensus on the treatment protocol for ossicular chain trauma. This study aims to investigate classification and strategies traumatic dislocation. We retrospectively analyzed 15 patients. Traumatic dislocations were categorized based location of trauma identified during surgery: Type I-ossicular without stapediovestibular dislocation; II-stapediovestibular dislocation (with or associated incus dislocation). Of 10 patients with I trauma, 9 experienced head 1 had a...
Objective To assess the effect of variable durations warm ischemia on renal function early after laparoscopic partial nephrectomy (LPN) and make definite safety duration ischemia. Methods The clinical data 76 patients treated with LPN from October 2012 to June 2014 were retrospectively analyzed. The divided into 3 groups based ischemic time, namely group A (28 cases) time less than 20 min, B (34 more min 30 C (14 min.LPN was performed artery clamping alone in all patients.Preoperative...
Objective To evaluate the effect of duloxetine on expression Toll-like receptor 4 (TLR4) in spinal dorsal horn a rat model diabetic neuropathic pain (DNP). Methods Type 2 diabetes mellitus was induced by high-fat and high-sucrose diet intraperitoneal streptozotocin (STZ) 35 mg/kg male Sprague-Dawley rats, aged months, weighing 180-220 g. Seventy-five rats with type were randomly divided into 5 groups (n=15 each) using random number table: group DNP, DNP + normal saline (group DNP+...
Objective To explore the technique,complications and preventions of CT guided percutaneous lung biopsy in diagnosing neoplasms.Methods 112 cases neoplasms were performed with shallow breathing.All pathological results complications recorded then followed clinical follow-up.Results 106 diagnosed malignant tumors initial pathology 6 non-malignant tumor.After second biopsies cases,4 confirmed 2 non-malignant.Of benign cases,1 was indicated during follow-up.The diagnosis accuracy rate 95.54％...
Background: Previous studies have found and confirmed a correlation between cognitive disorder chemotherapy. As genetic testing becomes more routine in clinical practice, targeted therapies are increasingly assuming prominence. The relationship treatment function is not yet clear. This study aims to investigate the by evaluating changes before after therapy.Methods: From screened cohort of 150 patients suffering from advanced non-small-cell lung cancer with gene mutations, 87 were rigorously...