A5081845032- Pain Mechanisms and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Neuropeptides and Animal Physiology
- Healthcare and Venom Research
- Pharmacological Effects of Natural Compounds
- Ion channel regulation and function
- Stroke Rehabilitation and Recovery
- Neuroinflammation and Neurodegeneration Mechanisms
- Axon Guidance and Neuronal Signaling
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Airway Management and Intubation Techniques
- Hip and Femur Fractures
- Peripheral Neuropathies and Disorders
- Medical and Biological Ozone Research
- Dermatology and Skin Diseases
- Bee Products Chemical Analysis
- Neurological Disease Mechanisms and Treatments
- Acupuncture Treatment Research Studies
- Medical Imaging and Analysis
- Pancreatic function and diabetes
- Hormonal and reproductive studies
- Foreign Body Medical Cases
- Acute Ischemic Stroke Management
- Inflammatory mediators and NSAID effects
- Diabetes Treatment and Management
Fujian Medical University
2021-2023
Xiamen University
2021
Children's Hospital of Chongqing Medical University
2021
Chongqing Medical University
2021
Affiliated Hospital of Hangzhou Normal University
2018
Air Force Medical University
2010-2017
Central post-stroke pain (CPSP) is an intractable and disabling central neuropathic that severely affects patients' lives, well-being, socialization abilities. However, CPSP has been poorly studied mechanistically its treatment remains challenging. Here, we used a rat model of induced by thalamic hemorrhage to investigate underlying mechanisms the effect stellate ganglion block (SGB) on emotional comorbidities.Thalamic was produced injecting collagenase IV into ventral-posterolateral nucleus...
Pain is one critical hallmark of inflammatory responses. A large number studies have demonstrated that stromal cell-derived factor 1 (SDF1, also named as CXCL12) and its cognate receptor C-X-C chemokine type 4 (CXCR4) play an important role in immune reaction processes. However, whether how SDF1–CXCR4 signaling involved pain remains unclear. Under the intraplantar (i.pl.) bee venom (BV) injection-induced persistent state, changes SDF1 CXCR4 expression cellular localization rat dorsal root...
Central post-stroke pain (CPSP) is an intractable central neuropathic that has been poorly studied mechanistically. Here we showed stromal cell-derived factor 1 (SDF1 or CXCL12), a member of the CXC chemokine family, and its receptor CXCR4 played key role in development maintenance thalamic hemorrhagic CPSP through hypoxia inducible 1α (HIF-1α) mediated microglial-astrocytic-neuronal interactions. First, both intra-thalamic collagenase (ITC) SDF1 injections could induce was blockable...
Central post-stroke pain (CPSP) is an intractable neuropathic pain, which can be caused by primary lesion of central somatosensory system. It also a common sequelae the thalamic hemorrhagic stroke (THS). So far, underlying mechanisms CPSP remain largely unknown. Our previous studies have demonstrated that SDF1-CXCR4 signaling in region contributes to maintenance THS hypersensitivity via mediation neuroinflammation. But whether spinal dorsal horn, initial point spinothalamic tract (STT),...
Ulinastatin, a broad-spectrum serine protease inhibitor, has been widely used to treat various diseases clinically. However, so far, the antinociceptive effect of ulinastatin remains less studied experimentally and underlying mechanisms for pain relief remain unclear. This study aimed find evidence analgesic on acute somatic visceral pain.The was evaluated by using formalin acetic acid-induced writhing test. The mechanism verified detecting peripheral inflammatory cell infiltration spinal...
Objective To discuss the correlation of surgical risk score with change T cell subsets and occurrence postoperative complications. Methods A total 260 patients hip fractures treated in our department were enrolled this study divided into high-risk group ( Group A) low-risk (Group B) based on score. The fasting peripheral venous blood was taken morning at one day before surgery days 1,3, 5, 7 14 after for measuring CD3, CD4 CD8 levels respectively two groups. In meantime, level changes...
Objective To explore the effects of optimizing thrombolytic nursing process in patients with acute cerebral infarct. Methods From January 2015 to 2017, we selected 80 infarct Emergency Department Affiliated Hospital Hangzhou Normal University as subjects by convenience sampling. Patients admitted from 2016 were control group and February 2017 observation group, 40 cases each group. Control received emergency routine nursing; on this basis that while optimized process. We compared time...
Background: There is no consensus regarding the optimal anesthetic approach to rigid bronchoscopy in children suffering from tracheobronchial FBA. We performed this meta-analysis assess efficacy and safety of different anesthesia agents ventilation modes for foreign body removal via young children. Methods: A systematic search three major databases all relevant articles. was analyze data. Results: Four trials evaluating anesthetics six two kinds were found. Compared with sevoflurane-based...