Ke Liao

ORCID: 0000-0003-1099-3491
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About
Contact & Profiles
Research Areas
  • Dementia and Cognitive Impairment Research
  • EEG and Brain-Computer Interfaces
  • Balance, Gait, and Falls Prevention
  • Functional Brain Connectivity Studies
  • Esophageal and GI Pathology
  • Cognitive Functions and Memory
  • Congenital Anomalies and Fetal Surgery
  • Human-Automation Interaction and Safety
  • Neuroscience of respiration and sleep
  • Organ Transplantation Techniques and Outcomes
  • Alzheimer's disease research and treatments
  • Motor Control and Adaptation
  • Gastrointestinal Tumor Research and Treatment
  • Neuroscience and Neural Engineering
  • Technology and Human Factors in Education and Health
  • Gaze Tracking and Assistive Technology
  • Foreign Body Medical Cases
  • Pediatric Hepatobiliary Diseases and Treatments
  • Tracheal and airway disorders
  • Musculoskeletal pain and rehabilitation
  • Memory and Neural Mechanisms
  • Gastric Cancer Management and Outcomes
  • Fatty Acid Research and Health
  • Image and Signal Denoising Methods
  • Cholangiocarcinoma and Gallbladder Cancer Studies

Imaging Center
2016-2024

Sichuan University
2005-2024

West China Hospital of Sichuan University
2020-2024

University of Kansas Medical Center
2016-2024

Harvard University
2022

University of Oklahoma
2012-2014

Soochow University
2005

Brain computer interface (BCI) is an assistive technology, which decodes neurophysiological signals generated by the human brain and translates them into control to external devices, e.g., wheelchairs. One problem challenging noninvasive BCI technologies limited dimensions from decoding movements of, mainly, large body parts, upper lower limbs. It has been reported that complicated dexterous functions, i.e., finger movements, can be decoded in electrocorticography (ECoG) signals, while it...

10.1371/journal.pone.0085192 article EN cc-by PLoS ONE 2014-01-08

Cognitive workload is increasingly recognized as an important determinant of performance in cognitive tests and daily life activities. a measure physical mental effort allocation to task, which can be determined through self-report or physiological measures. However, the reliability validity these measures have not been established older adults with wide range ability. The aim this study was establish test–retest National Aeronautics Space Administration Task Load Index (NASA-TLX) Activity...

10.3390/brainsci10120994 article EN cc-by Brain Sciences 2020-12-16

Abstract Long‐chain polyunsaturated fatty acids ( LCPUFA ) have been shown to be necessary for early retinal and brain development, but long‐term cognitive benefits of in infancy not definitively established. The present study sought determine whether supplementation during the first year life would result group differences behavior event‐related potentials ERP s) while performing a task requiring response inhibition (Go/No‐Go) at 5.5 years age. As newborns, 69 children were randomly...

10.1111/desc.12455 article EN Developmental Science 2016-10-16

Abstract The present study sought to determine whether supplementation of long‐chain polyunsaturated fatty acids (LCPUFA) during the first year life influenced brain function, structure, and metabolism at 9 years age. Newborns were randomly assigned consume formula containing either no LCPUFA (control) or with 0.64% total as arachidonic acid (ARA; 20:4n6) variable amounts docosahexaenoic (DHA; 22:6n3) (0.32%, 0.64%, 0.96% acids) from birth 12 months. At age (±0.6), 42 children enrolled in a...

10.1002/dev.21780 article EN Developmental Psychobiology 2018-10-11

Abstract Background Although growing evidence links beta-amyloid (Aβ) and neuronal hyperexcitability in preclinical mouse models of Alzheimer’s disease (AD), a similar association humans is yet to be established. The first aim the study was determine between elevated Aβ (Aβ+) cognitive processes measured by P3 event-related potential (ERP) cognitively normal (CN) older adults. second compare power CNAβ+ CNAβ−. Methods Seventeen participants (age: 73 ± 5, 11 females, Montreal Cognitive...

10.1186/s40035-022-00282-5 article EN cc-by Translational Neurodegeneration 2022-02-09

Background: Cognitive reserve may protect against cognitive decline. Objective: This cross-sectional study investigated the association between and physiological measures of workload in older adults with impairment. Methods: 29 impairment (age: 75±6, 11 (38%) women, MoCA: 20±7) 19 normal cognition 74±6; (58%) women; 28±2) completed a working memory test increasing task demand (0-, 1-, 2-back). was indexed using amplitude latency P3 event-related potential (ERP) at electrode sites Fz, Cz, Pz,...

10.3233/jad-220890 article EN Journal of Alzheimer s Disease 2023-01-24

The pupillary response reflects mental effort (or cognitive workload) during and/or motor tasks including standing postural control. EEG has been shown to be a non-invasive measure assess the cortical involvement of purpose this study was understand effect increasing task difficulty on and outcomes their relationship in young adults. Fifteen adults completed multiple trials standing: eyes open, open while performing dual-task (auditory two-back), occluded, occluded with dual-task....

10.3390/s22155594 article EN cc-by Sensors 2022-07-26

Event-related potentials (ERPs) offer unparalleled temporal resolution in tracing distinct electrophysiological processes related to normal and pathological cognitive aging. The stability of ERPs older individuals with a vast range ability has not been established. In this test-retest reliability study, 39 (age 74.10 (5.4) years; 23 (59%) women; 15 non β-amyloid elevated, 16 8 cognitively impaired) scores on the Montreal Cognitive Assessment (MOCA) ranging between 3 30 completed working...

10.3389/fnagi.2020.566391 article EN cc-by Frontiers in Aging Neuroscience 2020-10-19

Prader–Willi syndrome (PWS) is a neurodevelopmental genetic disorder characterized by multiple system involvement with hypotonia, poor suck feeding difficulties, growth and other hormone deficiencies, intellectual disability, behavioral problems childhood onset of hyperphagia resulting in obesity, if not externally controlled. Transcranial direct current stimulation (tDCS) has been increasingly shown to modulate cognitive processes children adults, including food-intake behaviors patients...

10.3390/brainsci11020250 article EN cc-by Brain Sciences 2021-02-17

BACKGROUND Esophageal chromoendoscopy with iodine solution is important for detecting early esophageal cancer. The effect of routine treatment lesions lightly stained Lugol’s limited, and the addition natural substances to a regular diet becoming increasingly common. Vinegar has antitumor effects as reported in previous studies. AIM To evaluate whether vinegar supplementation could improve prognosis patients lesions. METHODS This prospective single-centre trial included consecutive between...

10.4253/wjge.v16.i5.259 article EN World Journal of Gastrointestinal Endoscopy 2024-05-14

To investigate the effects of sensory reweighting on postural control and cortical activity in individuals with Parkinson's disease (PD) compared to age-matched controls using a virtual reality organization test (VR-SOT). Cross-sectional pilot study. University research laboratory. Ten participants idiopathic 11 age- sex-matched without neurologic disorders. Not applicable. Changes center pressure (COP) electroencephalography (EEG) (ie, power) alpha band theta/beta ratio recorded during...

10.1016/j.arrct.2024.100368 article EN cc-by-nc-nd Archives of Rehabilitation Research and Clinical Translation 2024-08-27

Abstract Cognitive workload (mental effort) is a measure of attention allocation to task, which can be administered through self-report or physiological measures. increasingly recognized as an important determinant performance in cognitive tests and daily life activities. However, the reliability validity these measures have not been established older adults with wide range ability. The aim this study was establish test-retest NASA-Task Load Index (NASA-TLX) Activity (ICA), extracted from...

10.1101/2020.10.26.20219881 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2020-10-27

Introduction: Offsprings from a prenatal docosahexaenoic acid (DHA) supplementation trial, in which pregnant women were assigned to placebo or 600mg DHA/day, followed determine the effect of DHA on behavior and brain function at 5.5 years (n=81 placebo, n=86 supplemented).Methods: Event-related potentials (ERP) recorded during visual task requiring button press (Go) frequent target stimuli response inhibition rare (No-Go). Univariate ANOVAs used test differences between group sex for...

10.1080/1028415x.2020.1712535 article EN Nutritional Neuroscience 2020-01-20

Automated vehicle (AV) technology may potentially improve road safety, independence, and mobility in older drivers with cognitive impairment (CI). Physiological sensors will be useful to provide feedback of the driver state AV controller system. The aim this study was compare changes cortical activity recorded using electro-encephalography (EEG) during conditional automation between adults normal cognition (NC) CI. Fourteen (age 72.43 (6.00); 10 (71%) women; nine NC five CI) completed two...

10.1016/j.trf.2023.06.004 article EN cc-by-nc-nd Transportation Research Part F Traffic Psychology and Behaviour 2023-06-15

Abstract Objective Pupillary response reflects mental effort (or cognitive workload) during challenging and postural control conditions. EEG is more established as a non-invasive measure to assess cortical involvement of control. The purpose this study was understand the pupillary under increasing task difficulty its relationship between outcomes in young adults. Methods Fifteen adults [age: 25.6 ± 2.9; sex: 10 males] completed multiple trials standing: eyes-open, eyes-open performing...

10.21203/rs.3.rs-1362889/v1 preprint EN cc-by Research Square (Research Square) 2022-03-02

We investigated the feasibility of discriminating four different motor imagery (MI) types from both hands using electroencephalography (EEG) through exploring underlying features related to MIs thumb and fist one hand. New spectral spatial were extracted principal component analysis (PCA) squared cross correlation (R <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> ). Extracted evaluated a linear discriminant (LDA) classifier, resulting...

10.1109/embc.2012.6346293 article EN Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2012-08-01

Abstract Event-related potentials (ERPs) offer unparalleled temporal resolution in tracing distinct electrophysiological processes related to normal and pathological cognitive aging. The stability of ERPs older individuals, who inherently show more intraindividual variability functions, has not been established. In this test-retest reliability study, 39 individuals (age 74.10 (5.4) years; 23 (59%) women; 15 non β-amyloid elevated, 16 8 cognitively impaired) with scores on the Montreal...

10.1101/2020.05.27.20109157 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2020-05-29

Abstract Aims Balance requires the cortical control of visual, somatosensory, and vestibular inputs. The aim this cross-sectional study was to compare contributions each these systems on postural activity using a sensory reweighting approach between participants with Parkinson’s disease (PD) controls. Methods Ten PD (age: 72 ± 9; 3 women; Hoehn &amp; Yahr: 2 [1.5 – 2.50]) 11 controls 70 3; 4 women) completed organization test in virtual reality (VR-SOT) while being recorded...

10.1101/2024.01.26.24301687 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2024-01-30

Abstract Incarcerated linea alba hernia is a rare form of ventral hernia. Most these contain pre-peritoneal fat or the omentum. Herniation containing ligamentum teres hepatis seldom seen. A 52-year-old man presented with an abdominal wall mass and dull pain for 2 weeks. Computed tomography ultrasound examination abdomen revealed epigastrium liver round ligament. hernial sac size 3 cm × 4 was explored by laparoscopic surgery successfully managed repair.

10.4103/jmas.jmas_35_24 article EN cc-by-nc-sa Journal of Minimal Access Surgery 2024-05-10

In this paper, a novel public digital color image watermark algorithm, by taking as watermark, is put forward, which the hidden layer carries much more information than it does words or characters. The algorithm based on principal component analysis of generalized Hebb adaptive in artificial neural network and to do quantitative coding for coefficients according proportion marginal textural image. addition, adaptively adjusts embedding depth images features ensure invisibility watermark. By...

10.1109/icia.2004.1373417 article EN 2005-04-06

Although most large submucosal tumors in the esophagus such as leiomyomas are benign, obstructive symptoms may develop owing to their size [1]. Endoscopic resection of remains difficult [2], and exophytic mid-esophagus worst. The main problem is presence important adjacent organs bronchus, aorta, spine. We report a novel concept for facilitating endoscopic resection: 3D-printed model guidance tumor (3DM-GTR). model, based on enhanced computed tomography, could clearly display anatomy details...

10.1055/a-1090-6940 article EN Endoscopy 2020-01-29

1Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu, China; 2Department Chengdu Second People's China. Correspondence: Bing Hu, MD. E-mail: [email protected]. Wu Wen, MM and Liansong Ye, MD, are co-first authors. SUPPLEMENTARY MATERIAL accompanies this paper at https://links.lww.com/AJG/C7.

10.14309/ajg.0000000000001302 article EN The American Journal of Gastroenterology 2021-05-20
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