A5015040819- Plant Pathogenic Bacteria Studies
- Phytoplasmas and Hemiptera pathogens
- Plant-Microbe Interactions and Immunity
- Insect-Plant Interactions and Control
- Plant Gene Expression Analysis
- Cocoa and Sweet Potato Agronomy
- Insect symbiosis and bacterial influences
- 3D Printing in Biomedical Research
- Meat and Animal Product Quality
- Food Waste Reduction and Sustainability
- Antioxidant Activity and Oxidative Stress
- Listeria monocytogenes in Food Safety
- Phytochemicals and Antioxidant Activities
- Agriculture Sustainability and Environmental Impact
- Plant Stress Responses and Tolerance
- Photodynamic Therapy Research Studies
- Botanical Studies and Applications
- Consumer Packaging Perceptions and Trends
- Polysaccharides Composition and Applications
- Water Treatment and Disinfection
- Helicobacter pylori-related gastroenterology studies
- Bacterial biofilms and quorum sensing
- Plant Pathogens and Fungal Diseases
- Phytochemical and Pharmacological Studies
- Renal and related cancers
Southern Medical University
2025
Nanfang Hospital
2025
Dale Bumpers National Rice Research Center
2024-2025
University of Georgia
2023-2024
Soochow University
2024
Ningbo University
2024
Sichuan University
2022-2023
West China Hospital of Sichuan University
2023
Florida Department of Citrus
2020-2022
University of Florida
2020-2022
Abstract Huanglongbing (HLB) is a devastating disease of citrus, caused by the phloem-colonizing bacterium Candidatus Liberibacter asiaticus (CLas). Here, we present evidence that HLB an immune-mediated disease. We show CLas infection Citrus sinensis stimulates systemic and chronic immune responses in phloem tissue, including callose deposition, production reactive oxygen species (ROS) such as H 2 O , induction immunity-related genes. The also upregulates genes encoding ROS-producing NADPH...
Abstract Photodynamic therapy (PDT) has significant potential in the treatment of dermatological, oncological, and nonneoplastic conditions through induction cell death, immune regulation, antimicrobial effects, etc. However, response some patients is unsatisfactory, there a lack an ideal protocol for multiple specific diseases (subtypes) to choose proper photosensitizer (PS), light source, dose. A thorough understanding underlying mechanism integral solving these problems, death gained much...
Gastric cancer is a prevalent malignancy that poses serious threat to global health.Despite advances in medical technologies, screening methods, and public awareness, gastric remains significant cause of morbidity mortality worldwide.Early frequently does not present with characteristic symptoms, while advanced stage disease characterized by dismal prognosis.As such, early great importance.In recent years, have been made globally both clinical basic research for the cancer.The current...
Abstract Organ-on-a-chip systems have been increasingly recognized as attractive platforms to assess toxicity and develop new therapeutic agents. However, current organ-on-a-chip are limited by a “single pot” design, which inevitably requires holistic analysis limits parallel processing. Here, we developed digital combining microwell array with cellular microspheres, significantly increased the parallelism over traditional for drug development. Up 127 uniform liver cancer microspheres in...
This study aimed to evaluate the effects of sea buckthorn on fermentative properties different lactic acid bacteria (LAB) and physicochemical characteristics fermented milk. Fermented milk was supplemented with 0% (v/v), 2.5%, 5% 7.5% using 8 LAB strains that isolated from 5 foods. Results showed addition in could significantly increase total phenolics contents (TPC), flavonoid (TFC) antioxidant activity, also made more redness yellowness. In addition, shorten coagulation time (from >9 h 4–5...
Huanglongbing (HLB), a bacterial disease caused by Candidatus Liberibacter asiaticus (CLas), is major threat to the citrus industry. In previous study conducted our laboratory, several transgenic trees expressing Arabidopsis thaliana NPR1 (AtNPR1) gene remained HLB-free when grown in field site under high HLB pressure. To determine molecular mechanisms behind AtNPR1-mediated tolerance HLB, transcriptome analysis was performed using AtNPR1 overexpressing and non-transgenic as control, from...
Major resistance (R) gene mediated to rice blast fungus Magnaporthe oryzae is often overcome by the due occurrences of new races with altered corresponding avirulence (AVR) genes. In this study, diseased tissue samples were collected from breeding stations and commercial fields in Arkansas, Louisiana, Puerto Rico during 2017-2019 determine efficacy major R genes, Pi-ta, Pik, Pizt, Pi9, Pi33. A total 185 isolates isolated examine existence AVR genes AVR-Pita1, AVR-Pib, AVR-Pik, AVR-Pizt,...
Streptomycin (STR) has been used to control citrus huanglongbing (HLB) caused by 'Candidatus Liberibacter asiaticus' (CLas) via foliar spray. Here, we studied the residue dynamics of STR and its effect on CLas titers in planta applied spray trunk injection 3-year-old trees that were naturally infected field. After spray, levels leaves peaked at 2 7 days postapplication (dpa) gradually declined thereafter. The did not significantly affect treated plants as determined quantitative PCR....
Abstract One of the common mechanisms to trigger plant innate immunity is recognition pathogen avirulence gene products directly by major resistance ( R ) genes in a for manner. In USA, genes, Pik-s, PiKh/m , and Pi-ta, Pi-39(t) Ptr have been effectively deployed prevent infections M. oryzae races, IB49, IC17 some time. Pi-9 only recently being provide overlapped complimentary Magnaporthe races IE1k USA. Pi-39(t), Pi9 are nuclear binding site-leucine rich (NLR) proteins, an atypical protein...
Abstract The priming of defence responses in pathogen‐challenged model plants undergoes a preparation phase and an expression for function. However, the response postharvest fruits has not been elucidated. Here, we found that 50 mM β‐aminobutyric acid (BABA) treatment could induce two distinct pathways linked with TGA1‐related systemic acquired resistance (SAR), resulting alleviation Rhizopus rot peach fruit. first was elicited by BABA alone, leading to enhanced transcription redox‐regulated...
Defense elicitors can induce fruit disease resistance to control postharvest decay but may incur quality impairment. Our present work aimed investigate the against Botrytis cinerea induced by elicitor β-aminobutyric acid (BABA) and elucidate specific transcriptional mechanism implicated in defense-related metabolic regulations. The functional dissection results demonstrated that, after inoculation with fungal necrotroph B. cinerea, a suite of critical genes encoding enzymes related sucrose...
Although renal fibrosis can advance chronic kidney disease and progressively lead to end-stage failure, no effective anti-fibrotic drugs have been clinically approved. To aid drug development, we developed a biomimetic progression model on-chip evaluate effects of natural killer cell-derived extracellular vesicles pirfenidone (PFD) across different fibrotic stages. First, the dynamic interplay between fibroblasts kidney-derived matrix (ECM) resembling fibrogenic niche demonstrated that...
Abstract Huanglongbing (HLB) or greening disease, associated with the bacterial pathogen Candidatus Liberibacter asiaticus (Las), is currently most devastating citrus disease worldwide and no cure available. Inducers of systemic acquired resistance (SAR) are effective sustainable to combat various plant diseases. In this study, SAR inducers acibenzolar-S-methyl (ASM), imidacloprid (IMI), 2,6-dichloroisonicotinic acid (INA), salicylic (SA), applied individually by foliar spray, soil drench...
The objectives of this study were to evaluate the inactivation efficacy a 405-nm light-emitting diode (LED) against Cronobacter sakazakii biofilm formed on stainless steel and determine sensitivity change illuminated food industrial disinfectants. results showed that LED illumination significantly reduced population viable cells, showing reduction 2.0 log (25°C), 2.5 (10°C), (4°C) between non-illuminated LED-illuminated groups at 4 h. Images confocal laser scanning microscopy electron...
Abstract The short neuropeptide F ( sNPF ) and NPF receptor NPFR genes play important roles in many physiological processes. However, information on the survival‐related functions of under different stress conditions is lacking aphids. In this study, we cloned , investigated expression levels these developmental stages, wing morphs, bird cherry‐oat aphid Rhopalosiphum padi L.), an agricultural pest. transcript varied among their alate females were significantly higher than those apterous...
Citrus Huanglongbing (HLB) is the most devastating citrus disease in world. Candidatus Liberibacter asiaticus (Las) prevalent HLB pathogen, which yet to be cultivated. A recent study demonstrates that Las does not contain pathogenicity factors are directly responsible for symptoms. Instead, triggers systemic and chronic immune responses, representing a pathogen-triggered disease. Importantly, overproduction of reactive oxygen species (ROS) causes cell death phloem tissues, thus causing...
Traditional methods for developing polymorphic microsatellite loci without reference sequences are time-consuming and labor-intensive, the polymorphisms of simple sequence repeat (SSR) developed from expressed tag (EST) databases generally poor. To address this issue, in study, we a new software (PSSRdt) established an effective method directly obtaining polymorphism details SSR by analyzing diverse transcriptome data. The includes three steps, raw data processing, PSSRdt application,...