A5016539413- Antibiotic Resistance in Bacteria
- Listeria monocytogenes in Food Safety
- Bacterial Infections and Vaccines
- Vibrio bacteria research studies
- Reproductive tract infections research
- Essential Oils and Antimicrobial Activity
- Salmonella and Campylobacter epidemiology
- Syphilis Diagnosis and Treatment
- Enterobacteriaceae and Cronobacter Research
- Infections and bacterial resistance
- Bacterial biofilms and quorum sensing
- Pharmaceutical and Antibiotic Environmental Impacts
- Child Nutrition and Water Access
- Infant Nutrition and Health
- Bacterial Identification and Susceptibility Testing
- Food Safety and Hygiene
- Escherichia coli research studies
- Bacteriophages and microbial interactions
- Plant Pathogenic Bacteria Studies
- Viral gastroenteritis research and epidemiology
- Antibiotic Use and Resistance
- Gut microbiota and health
- Identification and Quantification in Food
- Microbial Inactivation Methods
- Urinary Tract Infections Management
Institut Pasteur de Madagascar
2019-2024
Institut Pasteur of Shanghai
2022
Chinese Academy of Sciences
2022
Environmental Enteric Dysfunction (EED) refers to an incompletely defined syndrome of inflammation, reduced absorptive capacity, and barrier function in the small intestine. It is widespread among children adults low- middle-income countries also associated with poor sanitation certain gut infections possibly resulting abnormal microbiota, intestinal bacterial overgrowth (SIBO) stunting. We investigated pathogen exposure stunted non-stunted Antananarivo, Madagascar by collecting fecal...
Extended-spectrum b-lactamases (ESBL)-producing enterobacterales are considered a key indicator for antimicrobial resistance (AMR) epidemiological surveillance in animal, human and environment compartments. In this study we aim to investigate the presence genetic diversity of ESBL-producing on vegetable plants. We isolated beta-lactam resistant from several plants sequenced their whole genome. Utilizing cutting-edge genomic phylogenetic methods, sought i) characterize resistome plasmidome,...
ESBL-producing Escherichia coli (ESBL-Ec) is considered a key indicator for antimicrobial resistance (AMR) epidemiological surveillance in animal, human and environment compartments. There likelihood of ESBL-Ec animal-human transmission but proof cross-compartment still unclear.To characterize genetic similarity various compartments (humans, animals environment) from rural area Madagascar.We collected isolates prospectively humans, the (water) between April October 2018. These were subject...
The diffusion of extended-spectrum beta-lactamase (E-ESBL)-producing Enterobacteriaceae is a major concern worldwide, especially in low-income countries, where they may lead to therapeutic failures. In hospitals, colonization the highest, E-ESBL transmission poorly understood, limiting possibility establishing effective control measures. We assessed E-ESBL-acquisition routes neonatalogy ward Madagascar. Individuals from neonatology were longitudinally followed-up (August 2014-March 2015)....
A molecular analysis was performed of two Providencia rettgeri (P. rettgeri) strains (Pr 297 and Pr 269) collected in 2007 2009 from wound swabs patients admitted to the intensive care units at Joseph Ravoangy Andrianavalona hospital Military Hospital Antananarivo, Madagascar. The P. isolates were subjected susceptibility testing. Whole genome sequencing characterise antibiotic resistance genes, genomic islands mobilomes (integrons, plasmids insertion sequences). All found be...
Abstract Background In Southeast-Asia, where many conditions associated with dissemination of ESBL-producing Enterobacterales (ESBL-E) in the community are met, data from scarce but show high ESBL-E carriage prevalence. Maternal colonization is considered a risk factor for neonatal colonization, which first step towards developing sepsis. Despite this, prevalence and its factors during pregnancy or postpartum remain undefined Southeast-Asia. Objectives To estimate faecal among peripartum...
Listeriosis constitutes a significant public health threat due to its high mortality rate. This study investigates the microbiological and genomic characteristics of Listeria monocytogenes isolates in Madagascar, where listeriosis is notifiable disease. The analysis focuses on fatal case meningeal 12-year-old child. Genomic revealed novel cgMLST type (L2-SL8-ST8-CT11697; CC8, serogroup Iia) with typical virulence antibiotic resistance profiles. These isolates, unique formed an independent...
Listeriosis constitutes a significant public health threat due to its high mortality rate. This study investigates the microbiological and genomic characteristics of Listeria monocytogenes isolates in Madagascar, where listeriosis is notifiable disease. The analysis focuses on fatal case meningeal 12-year-old child. Genomic revealed novel cgMLST type (L2-SL8-ST8-CT11697; CC8, serogroup Iia) with typical virulence antibiotic resistance profiles. These isolates, unique formed an independent...
Listeriosis constitutes a significant public health threat due to its high mortality rate. This study investigates the microbiological and genomic characteristics of Listeria monocytogenes isolates in Madagascar, where listeriosis is notifiable disease. The analysis focuses on fatal case meningeal 12-year-old child. Genomic revealed novel cgMLST type (L2-SL8-ST8-CT11697; CC8, serogroup Iia) with typical virulence antibiotic resistance profiles. These isolates, unique formed an independent...
Objectives Antimicrobial-resistant Neisseria gonorrhoeae (NG) is a concern. Little known about antimicrobial susceptibility profiles and associated genetic resistance mechanisms of NG in Madagascar. We report data isolates obtained by the medical laboratory (CBC) Institut Pasteur de Madagascar, Antananarivo, during 2014–2020. present phenotype subset isolates. Methods retrieved retrospective (N=395) from patients with isolated 2014−2020 CBC. retested 46 viable including 6 found ceftriaxone 2...
We report here the draft genome sequence of a Chryseobacterium indologenes strain, isolated from blood culture 2.2-year-old child admitted to hospital for vomiting and coughing. The was composed 5,063,674 bp had 37.04% GC content. detected 4,796 genes with predicted protein-coding functions, including those associated antibiotic resistance.
ABSTRACT Stenotrophomonas maltophilia has been recognized as an emerging multidrug resistant organism in hospital settings due to its resistance a broad range of antimicrobial agents. These include β-lactams and aminoglycosides, afforded by the existence intrinsic acquired mechanisms. Trimethoprim/sulfamethoxazole (SXT) is recommended one best treatment choices against S. infections; however increasing SXT complicated treatment. From July 2014 March 2015, individuals surfaces from...
Background: Extended-spectrum β-lactamase-producing Escherichia coli (ESBL- Ec) is considered a key indicator for antimicrobial resistance (AMR) epidemiological surveillance in animal, humans and environment sectors. Likelihood ESBL- Ec animal–human transmission pointed but proofs of cross-sectors are still unclear. Here, we aimed to characterize genetic similarity connected humans, animals sectors from rural area Madagascar. Methods: We implemented cross-sectional population-based study...
2 Abstract The antimicrobial resistance of Neisseria gonorrhoea to all classes current available antibiotics is a global concern. National surveillance programmes monitoring the susceptibility profiles gonorrhoeae hardly exist in resource constraint settings. Therefore, little known about profile and associated genetic mechanisms N. Madagascar. We report data isolates obtained by medical laboratory Institut Pasteur de Madagascar, from 2014 -2020. In addition, we present on subset (N=46),...