A5027831644- Global Maternal and Child Health
- Tuberculosis Research and Epidemiology
- Pneumonia and Respiratory Infections
- Maternal and Perinatal Health Interventions
- Respiratory viral infections research
- Diagnosis and treatment of tuberculosis
- Neonatal and Maternal Infections
- Antibiotic Resistance in Bacteria
- Infectious Diseases and Tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Burkholderia infections and melioidosis
- Child Nutrition and Water Access
- Maternal and fetal healthcare
- Family and Patient Care in Intensive Care Units
- Antibiotic Use and Resistance
- Viral gastroenteritis research and epidemiology
- COVID-19 epidemiological studies
- Family Support in Illness
- Hepatitis B Virus Studies
- Anorectal Disease Treatments and Outcomes
- Viral Infections and Outbreaks Research
- Ureteral procedures and complications
- Mycobacterium research and diagnosis
- Chemical Looping and Thermochemical Processes
- Healthcare Systems and Practices
Laboratoire d'Annecy-le-Vieux de Physique Théorique
2015-2023
Institut Pasteur du Cambodge
2011-2021
Institut Pasteur
2011-2018
Assistance Publique – Hôpitaux de Paris
2018
Institut Pasteur de Dakar
2018
Université Paris Cité
2018
Hôpital Necker-Enfants Malades
2018
Institut Pasteur de Madagascar
2018
Children's Hospital Colorado
2017
University of Colorado Denver
2017
Background. The diagnosis of tuberculosis in human immunodeficiency virus (HIV)-infected children is challenging. We assessed the performance alternative specimen collection methods for HIV-infected using Xpert MTB/RIF (Xpert). Methods. aged ≤13 years with suspected intrathoracic were enrolled 8 hospitals Burkina Faso, Cambodia, Cameroon, and Vietnam. Gastric aspirates taken <10 expectorated sputum samples ≥10 (standard samples); nasopharyngeal aspirate stool all children, a string test was...
Salmonella enterica is a leading cause of human gastroenteritis. S. strains that produce ESBLs (ESBL-Salm) remain rare in Europe and North America, but less known about their prevalence among animal-derived foods countries with weaker food safety practices unregulated veterinary antibiotic use. To examine the characteristics ESBL-Salm from retail meats Phnom Penh, Cambodia. We tested fish, pork chicken two markets for ESBL- carbapenemase-producing September–December 2016, using cefotaxime-...
First documented in 1741, the practice of episiotomy substantially increased worldwide during 20th century. However, research shows that is not effective reducing severe perineal trauma and may be harmful. Using a mixed-methods approach, we conducted study 2013–14 on why obstetricians midwives large maternity hospital Phnom Penh, Cambodia, still do routine episiotomies. The included extent practice, based medical records; retrospective analysis delivery notes random sample 365 patients; 22...
Abstract Background Melioidosis is a disease caused by Burkholderia pseudomallei and considered endemic in South-East Asia but remains poorly documented Cambodia. We report the first series of hospitalized pulmonary melioidosis cases identified Cambodia describing clinical characteristics outcomes. Methods characterized acute lower respiratory infections (ALRI) that were through surveillance two provincial hospitals. Severity was defined systolic blood pressure, cardiac frequency, rate,...
SUMMARY Robust disease burden estimates are important for decision-making concerning introduction of new vaccines. Dengue is a major public health problem in the tropics but robust lacking. We conducted two-sample, capture–recapture study largest province Cambodia to determine under-recognition National Surveillance System (NDSS). During 2006–2008, community-based active surveillance acute febrile illness was 0- 19-year-olds rural and urban areas combined with testing dengue virus infection....
Exclusive breastfeeding, one of the best natural resources, needs protection and promotion. The International Code Marketing Breast-milk Substitutes (the Code), which aims to prevent undermining breastfeeding by formula advertising, faces implementation challenges. We reviewed frequently overlooked challenges obstacles that is facing worldwide, but particularly in Southeast Asia. Drawing lessons from various countries where we work, following example successful public health interventions,...
Diagnosis of tuberculosis should be improved in children infected with HIV to reduce mortality. We developed prediction scores guide antituberculosis treatment decision HIV-infected suspected tuberculosis.HIV-infected enrolled Burkina Faso, Cambodia, Cameroon, and Vietnam (ANRS 12229 PAANTHER 01 Study), underwent clinical assessment, chest radiography, Quantiferon Gold In-Tube (QFT), abdominal ultrasonography, sample collection for microbiology, including Xpert MTB/RIF (Xpert). 4 diagnostic...
In many Asian countries, Klebsiella pneumoniae (KP) is the second pathogen responsible for community-acquired pneumonia. Yet, very little known about KP etiology in ALRI Cambodia, a country that has one of weakest medical infrastructures region. We present here first clinico-radiological description hospitalized Cambodian patients.Through surveillance two provincial hospitals, was isolated from sputum and blood cultures, identified by API20E gallery patients ≥ 5 years-old with fever...
Viruses are detected in most hospitalized children admitted for acute respiratory infections. Etiologic understanding is needed to improve clinical management and prevention, particularly resource-limited tropical countries.A 3-year prospective descriptive study was conducted among Cambodian 2 provincial hospitals lower tract infection. Molecular detection 18 viral pathogens using multiplex polymerase chain reaction/reverse transcription reactions performed.We enrolled 1006 less than 5 years...
This case study describes the health response provided by Ministry of Health Nepal with support from UN agencies and several other organisations, to 1.4 million women adolescent girls affected major earthquake that struck in April 2015. After a post-disaster needs assessment, was cater for identified sexual reproductive (RH) needs, following guidance Minimum Initial Service Package RH developed global Inter-Agency Working Group. We describe initiatives implemented resume services:...
C-sections are an increasingly performed medical practice which can save lives but may also lead to major complications. Through a mixed methods study conducted in 2015 Cambodia, we aimed analyze the reasons for requesting c-section and explore factors that associated with c-sections. 60% of women cohort who gave birth by reported having requested it. 31 in-depth interviews, determined given before during labour. Before labour, were: choosing delivery date; bringing luck joy family;...
Introduction: In Cambodia, we implemented a pilot surveillance of superficial surgical site infections (SSSI) following caesarean deliveries (CD) in provincial hospital, to estimate their incidence, describe clinical management, and determine causative pathogens. Methodology: Between October 2010 February 2011, all women admitted for CD were included the surveillance. Their condition was monitored post-operative period 30 days, including two assessments performed by surgeons. Cases...
Few data exist on viral and bacterial etiology of acute lower respiratory infections (ALRI) in ≥5 year –old persons the tropics. We conducted active surveillance community-acquired ALRI two hospitals Cambodia, a low-income tropical country. Patients were tested for acid-fast bacilli (AFB) by direct sputum examination, other bacteria blood and/or cultures, viruses using molecular techniques nasopharyngeal/throat swabs. Pulmonologists reviewed clinical/laboratory interpreted chest X-rays (CXR)...
Vaccination reduces mortality from infectious disease, which is the leading cause of death in children under 5 and bears a particularly high burden low- middle-income countries. The Global Vaccine Action Plan (2011-2020) has set target 90% vaccine coverage for all vaccines included national immunization programs by 2020. objectives this study were to estimate among Madagascar, Cambodia, Senegal identify risk factors associated with incomplete vaccination.
Abstract Severe bacterial infections are a leading cause of death among neonates in low-income countries, which harbor several factors to emergence and spread multidrug-resistant bacteria. Low-income countries should prioritize interventions decrease neonatal infections; however, data scarce, specifically from the community. To assess incidence, etiologies, antimicrobial drug–resistance patterns infections, during 2012–2014, we conducted community-based prospective investigation 981 newborns...
To evaluate inter-reader agreement and diagnostic accuracy of chest radiography (CXR) in the diagnosis tuberculosis (TB) children with human immunodeficiency virus (HIV) infection.HIV-infected clinically suspected TB were enrolled a prospective study conducted Burkina Faso, Cambodia, Cameroon Viet Nam from April 2010 to December 2014. Three readers-a local radiologist, paediatric pulmonologist radiologist-independently reviewed CXRs. Inter-reader was then assessed using κ coefficient....
Background Severe bacterial infections (SBIs) are a leading cause of neonatal deaths in low- and middle-income countries (LMICs). However, most data came from hospitals, which do not include neonates who did seek care or were treated outside the hospital. Studies community scarce, few among those available conducted with high-quality microbiological techniques. The burden SBI at level is therefore largely unknown. We aimed here to describe incidence, etiology, risk factors, antibiotic...