A5100344289- Head and Neck Cancer Studies
- Distributed Control Multi-Agent Systems
- Neural Networks Stability and Synchronization
- Multiple Myeloma Research and Treatments
- Peptidase Inhibition and Analysis
- Model Reduction and Neural Networks
- Reproductive System and Pregnancy
- Pregnancy and preeclampsia studies
- Quinazolinone synthesis and applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Lung Cancer Research Studies
- Mathematical and Theoretical Epidemiology and Ecology Models
- Birth, Development, and Health
- Assisted Reproductive Technology and Twin Pregnancy
- Protein Degradation and Inhibitors
- Nonlinear Dynamics and Pattern Formation
- Prenatal Screening and Diagnostics
- Cell Adhesion Molecules Research
- TGF-β signaling in diseases
- Advanced Memory and Neural Computing
- Cancer Mechanisms and Therapy
- Autophagy in Disease and Therapy
- Respiratory viral infections research
- Mathematical Biology Tumor Growth
- Gastric Cancer Management and Outcomes
Chengdu Women's and Children's Central Hospital
2025
University of Electronic Science and Technology of China
2025
Nanjing Medical University
2024-2025
Fuzhou University
2022-2024
Shandong University
2012-2024
Shandong Women’s University
2024
First Affiliated Hospital of Gannan Medical University
2022-2024
Beijing Chest Hospital
2024
Capital Medical University
2024
Qujing Normal University
2024
Respiratory syncytial virus (RSV) represents a substantial global health challenge, with disproportionately high disease burden in low-income and middle-income countries. RSV exhibits seasonality most areas globally, comprehensive understanding of within-country variations could help to define the timing immunisation programmes. This study focused on China, aimed describe geographical distribution seasonality, identify distinct transmission zones, evaluate potential suitability seasonal...
Abstract The COVID-19 pandemic and relevant non-pharmaceutical interventions (NPIs) interrupted the circulation of common respiratory viruses. These viruses demonstrated an unprecedented asynchronous resurgence as NPIs were relaxed. We compiled a global dataset from systematic review, online surveillance reports unpublished data Respiratory Virus Global Epidemiology Network, encompassing 92 sites. compared timings within each site synthesised differences in across sites, using generalised...
Scavenger receptor class B type I (SR-BI) has been linked to the development and progression of breast cancer. However, its clinical significance in cancer remains unclear. Here, we evaluated SR-BI expression a well-characterized tissue microarray by immunohistochemistry. High was observed 54 % all cases significantly associated with advanced pTNM stage (P = 0.002), larger tumor size 0.023), lymph node metastasis 0.012), absence ER 0.014). The Kaplan–Meier survival analysis revealed that...
Abstract Background The liver is the central organ for cholesterol homoeostasis, and its dysfunction might cause pathological alterations including hepatocellular carcinomas (HCCs). 3β-hydroxysteroid-Δ24 reductase (DHCR24), a crucial enzyme of biosynthetic pathway, involved in lipid rafts formation. Genkwadaphnin (GD) daphnane diterpene isolated from flower buds Daphne genkwa Siebold et Zuccarini (Thymelaeaceae). Methods We evaluated vitro vivo effect GD using HCC cells BALB/c nude mice....
Abstract Background During human early placentation, a proportion of extravillous trophoblasts (EVTs) migrate to the maternal decidua, differentiating into endovascular EVTs remodel spiral arteries and ensure establishment blood circulation at maternal-fetal interface. Inadequate EVT migration differentiation are closely associated with adverse pregnancy outcomes such as miscarriage. Activin A fibronectin both secretory molecules abundantly expressed has been reported regulate biological...
The renal glomerular capillary endothelium is part of the filtration barrier and involved in acute chronic inflammation glomerulus. Glomerular endothelial cells are a unique type microvascular cell, which remain to be fully characterized. aim present study was examine permeability their responses interleukin (IL)‑1β, pro‑inflammatory cytokine. Human cell (HRGEC) human umbilical vein (HUVEC) monolayers were examined using Transwell assay, transendothelial electrical resistance (TEER) by...
This paper mainly investigates the consensus of second-order multi-agent systems by using neighbours' information. The comparison between convergence rate neighbour protocol and one general is developed. When system achieves maximum speed consensus, relation parameter in that analysed. If there exists delay communication, margins are derived. Numerical examples given to illustrate effectiveness proposed methods.
The parathyroid glands are important endocrine for maintaining calcium and phosphorus metabolism, they vulnerable to accidental injuries during thyroid cancer surgery. aim of this retrospective study was investigate the application high-frequency ultrasound imaging preoperative anatomical localization in patients with analyze protective effect technique on its reducing postoperative complications.A total 165 who were operated our hospital included. assigned into two groups according time...
The aim of this study was to investigate the influence NUDT15 R139C, thiopurine S-methyltransferase (TPMT), and 6-TGN on azathioprine (AZA) induced leukopenia in Chinese autoimmune patients. Among 87 enrolled patients, 23 (26.4%) had leukopenia. R139C variant associated with (p = 1.86 × 10-7; OR: 7.59; 95% CI: 3.16-18.21). However, TPMT genotype not shown be correlated incidence 0.95). There no significant difference concentration between patients or without 0.15) association found variants...
Serum cytokine profile and T helper (Th)1/Th2 cell balance are related to the success of embryo implantation, although not yet firmly linked recurrent implantation failure (RIF), a repeated achieve clinical pregnancy following multiple high-quality transfer. In this prospective study, comprehensive bioinfomatic analysis logistic regression were used compare serum profiles 41 RIF patients with those 29 subjects first-cycle successful in mid-luteal phase assess alterations at five weeks...
Aeromonas caviae (A. caviae) is one of the major etiological agents in human intestinal infections reported to be associated with a broad spectrum extra-intestinal increasing incidence over recent years. Although previous studies have established its significance as causative agent both bloodstream and gastrointestinal infections, characteristics A. that cause remain unilluminated.In this single-center retrospective study, we investigated epidemiological characteristics, antimicrobial...
Tourism development provides a unique context for studying guanxi in acquaintance society rural areas China. Taking the case of Moon village from perspective guanxi, this study conducted qualitative to analyze structural characteristics semi-acquaintance tourism context. A buffer circle develops when strangers immerse themselves into an acquaintance-based through social interaction, where affection and reasoning define boundary, interests on which consensus is based, as well elite collective...
The aim of the study was to determine effect tetramethylpyrazine phosphate tablets (TPT), a Chinese medicine used for cardiovascular disease, on immunity activity and oxidative injury in rats. Heart failure (HF) induced by isoproterenol (ISO). After animal model established, rats were administered TPT gavage (once day). results indicated that improved left ventricular systolic pressure (LVSP), end-diastolic (LVEDP), ±dP/dt, heart weight/body weight. could decrease levels tumor necrosis...
Angiogenesis is required for the growth and metastasis of solid tumors. The anti-malarial agent dihydroartemisinin (DHA) demonstrates potent anti-angiogenic activity, but underlying molecular mechanisms are not yet fully understood. During process angiogenesis, endothelial cells migrating from existing capillaries may undergo programmed cell death after detaching extracellular matrix, a that defined as anchorage-dependent apoptosis or anoikis. In present study, DHA-induced was compared in...
OBJECTIVE To investigate the risk factors of lymph node metastasis (LNM) in early gastric carcinoma (EGC) a Chinese population. METHODS The data were analyzed to determine LNM. patients’ characteristics, tumor's location, gross features, histological type, differentiation, invasive depth, lymphovascular invasion (LVI), perineural and numbers nodes retrieved involved statistically analyzed. RESULTS A total 734 patients with EGC finally enrolled study, LNM was present 14.2% (104/734) them. By...
To investigate clinical features, independent associated factors, treatment, and outcome of patients with peripheral neuropathy (PN) in eosinophilic granulomatosis polyangiitis (EGPA). We retrospectively analyzed data 110 EGPA from 2007 to 2019 Peking Union Medical College Hospital. The factors PN were univariate multivariate logistic regressions. In PN, paresthesia muscle weakness observed 82% 33% patients, respectively. Both the upper lower limbs involved 51% patients. 30% had symmetrical...