A5050777141- Respiratory viral infections research
- COVID-19 epidemiological studies
- Vaccine Coverage and Hesitancy
- Influenza Virus Research Studies
- Viral Infections and Vectors
- Pneumonia and Respiratory Infections
- SARS-CoV-2 and COVID-19 Research
- Hepatitis B Virus Studies
- Research on Leishmaniasis Studies
- Hepatitis C virus research
- Diabetes Management and Research
- Clostridium difficile and Clostridium perfringens research
- Viral gastroenteritis research and epidemiology
- Viral Infections and Outbreaks Research
- Diabetes and associated disorders
- Bacterial Identification and Susceptibility Testing
- Diabetes Treatment and Management
- Congenital Diaphragmatic Hernia Studies
- Cardiovascular Function and Risk Factors
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Lung Cancer Diagnosis and Treatment
- Rabies epidemiology and control
- Gastrointestinal Bleeding Diagnosis and Treatment
- HIV, Drug Use, Sexual Risk
- Physical Education and Training Studies
National Center for Disease Control and Public Health
2014-2025
Tbilisi State Medical University
2025
The 2009 H1N1 pandemic highlighted the need to routinely monitor severe influenza, which lead establishment of sentinel hospital-based surveillance acute respiratory infections (SARI) in several countries Europe. objective this study is describe characteristics SARI patients and explore risk factors for a outcome influenza-positive patients.Data on hospitalised meeting syndromic case definition between 2012 from nine Eastern Europe (Albania, Armenia, Belarus, Georgia, Kazakhstan, Kyrgyzstan,...
This study investigated the transmission and prevalence of Leishmania parasite infection humans in two foci Visceral Leishmaniasis (VL) Georgia, well known focus Tbilisi East, Kutaisi, a new West country. The seroprevalence canine leishmaniasis was order to understand zoonotic transmission. Blood samples 1575 dogs (stray pet) 77 wild canids were tested for VL by Kalazar Detect rK39 rapid diagnostic tests. Three districts one Kutaisi. highest proportions seropositive pet present District #2...
The country of Georgia initiated its hepatitis C virus (HCV) elimination program in 2015, at which point a serosurvey showed the adult prevalence HCV antibody (anti-HCV) and RNA to be 7.7% 5.4%, respectively. This analysis reports results follow-up conducted 2021, progress towards elimination.
Background: Type 1 diabetes (T1D) is characterized by the selective destruction of insulin-secreting beta cells in pancreas. The exact mechanisms underlying T1D are not fully clarified; however, it widely accepted that type caused combination genetic and environmental factors. Individuals with have an elevated risk developing cardiovascular diseases (CVD) a reduced life expectancy.Our research aims to review interrelationship between children.Methods:We performed comprehensive literature...
Introduction Understanding COVID-19 vaccine effectiveness (VE) in healthcare workers (HCWs) is critical to inform vaccination policies. We measured VE against laboratory-confirmed symptomatic infection HCWs the country of Georgia from January – June 2022, during a period Omicron circulation. Methods conducted cohort study six hospitals Georgia. were enrolled early 2021. Participants completed weekly symptom questionnaires. Symptomatic tested by RT-PCR and/or rapid antigen test (RAT). also...
Background Georgia has adopted the World Health Organization European Region’s and global goals to eliminate viral hepatitis. A nationwide serosurvey among adults in 2015 showed 2.9% prevalence for hepatitis B virus (HBV) surface antigen (HBsAg) 25.9% antibodies against HBV core (anti-HBc). infection children had previously not been assessed. Aim We aimed assess update estimates Georgia. Methods This cross-sectional conducted 2021 persons aged ≥ 5 years used multi-stage stratified cluster...
Background Severe Acute Respiratory Infection (SARI) causes substantial mortality and morbidity worldwide. The country of Georgia conducts sentinel surveillance to monitor SARI activity changes in its infectious etiology. This study characterizes the epidemiology over 2015/16 2016/17 influenza seasons, compares clinical presentations by etiology, estimates vaccine effectiveness using a test-negative design. Methods cases were selected through alternate day systematic sampling between...
In Georgia, an upper-middle income European country, the COVID-19 vaccine rollout began on 15 March 2021 with health workers (HWs), a priority group for vaccination. We assessed factors associated vaccination among HWs at six large hospitals in early stages of (March−July 2021). Among 1533 HWs, 274 (17.9%) had received one dose vaccine. Strong independent predictors uptake were age > 40 years, especially 50−59 years old (aOR 2.40, 95% CI 1.50−3.88), considering as “somewhat effective” or...
Background Healthcare workers (HCWs) have suffered considerable morbidity and mortality during the COVID-19 pandemic. Few data on vaccine effectiveness (VE) are available from middle-income countries in WHO European Region. We evaluated primary series VE against laboratory-confirmed among HCWs Georgia. Methods six hospitals Georgia were invited to enroll a prospective cohort study conducted March 19–December 5, 2021. Participants completed weekly symptom questionnaires. Symptomatic tested by...
This study has evaluated the correlation between different carbapenemases detection methods on carbapenem non-susceptible Klebsiella pneumoniae strains from Northern and Eastern Europe; 31 institutions in 9 countries participated research project, namely Finland, Estonia, Latvia, Lithuania, Russia, St. Petersburg, Poland, Belarus, Ukraine, Georgia. During program, a total of 5,001 clinical K. isolates were screened for any non-susceptibility by disk diffusion method, Vitek 2 or Phoenix...
Leishmaniasis includes multiple clinical syndromes, most notably visceral, cutaneous, and mucosal forms. Visceral leishmaniasis (VL), also known as kala-azar, is a potentially fatal disease endemic to large parts of Africa Asia, in South-Eastern Europe (Greece, Turkey, Georgia). parasitic zoonosis caused by species the L. donovani complex. In classical epidemiological model main reservoir for VL are canines. The study included cohort 513 individuals both genders (190 males 323 females) from...
Background Influenza epidemiological and virologic data from Georgia are limited. We aimed to present Like Illness (ILI) Severe Acute Respiratory Infection (SARI) surveillance characterize influenza viruses circulating in the country over three seasons. Methods analyzed sentinel site ILI SARI for 2014–2017 seasons Georgia. Patients' samples were screened by real-time RT-PCR isolated characterized antigenically haemagglutination inhibition assay genetically sequencing of HA NA genes. Results...
Due to reports of substandard influenza preparedness, the country Georgia developed two surveillance systems. This paper describes these systems in their capacity detect influenza.Two for operate Georgia: an influenza-like illness (ILI) sentinel system out-patient cases, based capital, Tbilisi, and a severe acute respiratory infection (SARI) in-patient cases with five sites - one four Kutaisi. Patients provide samples laboratory testing, including confirmation.From 2015-2016, 825 were...
Infections caused by viruses of the parapoxvirus (PPV) genus, including orf and pseudocowpox viruses, are frequently seen in both humans animals many regions world. These infections often misdiagnosed or neglected because lack clinician awareness, inadequate diagnostic capacity, their relatively mild disease presentation, which may result affected individuals not seeking medical attention. Although PPV should be routinely considered patients with cutaneous lesions, especially those who have...
Influenza virus infection is an important cause of under-five mortality. Maternal vaccination protects children younger than 3 months age from influenza infection. However, it unknown to what extent paediatric influenza-related mortality may be prevented by a maternal vaccine since global age-stratified data are lacking.We invited clinicians and researchers share clinical demographic characteristics 5 years who died with laboratory-confirmed between January 1, 1995 March 31, 2020. We...
Background Healthcare workers (HCWs) have suffered considerable morbidity and mortality during the COVID-19 pandemic. Few data on vaccine effectiveness (VE) are available from middle-income countries in Europe. We evaluated primary series VE against laboratory-confirmed among HCWs Georgia. Methods six hospitals Georgia were invited to enroll a prospective cohort study conducted March 19–December 5, 2021. Participants completed weekly symptom questionnaires. Symptomatic tested by RT-PCR...
Background Healthcare workers (HCWs) have suffered considerable morbidity and mortality during the COVID-19 pandemic. Few data on vaccine effectiveness (VE) are available from middle-income countries in Europe. We evaluated primary series VE against laboratory-confirmed among HCWs Georgia. Methods six hospitals Georgia were invited to enroll a prospective cohort study conducted March 19–December 5, 2021. Participants completed weekly symptom questionnaires. Symptomatic tested by...
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Introduction Understanding COVID-19 vaccine effectiveness (VE) in healthcare workers (HCWs) is critical to inform vaccination policies. We measured VE against laboratory-confirmed symptomatic infection HCWs the country of Georgia from January – June 2022, during a period Omicron circulation. Methods conducted cohort study six hospitals Georgia. were enrolled early 2021. Participants completed weekly symptom questionnaires. Symptomatic tested by RT-PCR and/or rapid antigen test (RAT). also...