A5100708321- Spinal Fractures and Fixation Techniques
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Esophageal Cancer Research and Treatment
- Spine and Intervertebral Disc Pathology
- MicroRNA in disease regulation
- Pediatric Hepatobiliary Diseases and Treatments
- Infectious Diseases and Tuberculosis
- X-ray Diffraction in Crystallography
- Hepatocellular Carcinoma Treatment and Prognosis
- Genetic and Kidney Cyst Diseases
- Liver Disease Diagnosis and Treatment
- Esophageal and GI Pathology
- Genetic factors in colorectal cancer
- interferon and immune responses
- Sarcoma Diagnosis and Treatment
- Occupational and environmental lung diseases
- Cancer-related molecular mechanisms research
- Helicobacter pylori-related gastroenterology studies
- Crystallization and Solubility Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Tuberous Sclerosis Complex Research
- Vascular Tumors and Angiosarcomas
- Wnt/β-catenin signaling in development and cancer
- Endoplasmic Reticulum Stress and Disease
- Cancer Diagnosis and Treatment
Zhongnan Hospital of Wuhan University
2021-2025
Wuhan University
2021-2025
Beijing Institute of Neurosurgery
2025
Capital Medical University
2025
Qingdao University of Science and Technology
2025
Second Xiangya Hospital of Central South University
2019-2024
Central South University
2019-2024
University of South China
2022
Wuhan Prevention and Treatment Center for Occupational Diseases
2022
Beijing University of Chinese Medicine
2019
Indocyanine green (ICG) fluorescence imaging technology is increasingly widely used in laparoscopic hepatectomy. However, whether it can provide long-term survival benefits to patients with liver malignancies remains unclear. This study investigated the clinical effect of hepatectomy for hepatocellular carcinoma (HCC) using ICG technology. We retrospectively analyzed HCC who underwent at Zhongnan Hospital Wuhan University from January 2016 December 2020. Propensity score matching (PSM) was...
Abstract Hepatocellular carcinoma (HCC) is a highly lethal malignant tumor, and the current non‐invasive diagnosis method based on serum markers, such as α‐fetoprotein (AFP), des‐γ‐carboxy‐prothrombin (DCP), has limited efficacy in detecting it. Therefore, there critical need to develop novel biomarkers for HCC. Recent studies have highlighted potential of exosomes biomarkers. To enhance exosome enrichment, silicon dioxide (SiO 2 ) microsphere‐coated three‐dimensional (3D) hierarchical...
ABSTRACT Hepatectomy is a critical treatment for liver cancer, but achieving complete tumor removal remains challenging. The development of tumor‐targeting probes capable accurately identifying locations and providing real‐time intraoperative navigation significant clinical importance. We synthesize tumor‐targeted probe by conjugating fibroblast activation protein inhibitor (FAPI) with near‐infrared organic room temperature phosphorescence (RTP) material. then analyze its surgical...
Linxian, China, has one of the highest rates esophageal cancer in world. Other authors have described high prevalences histologic esophagitis, atrophy, and dysplasia Linxian suggested that these findings may represent precancerous lesions this population. In 1987, a new endoscopic survey allowed to make an independent study histology Linxian.There were 1567 satisfactory squamous biopsies available from 754 patients. These classified as normal, acanthosis, dysplasia, or cancer.Classified by...
We reviewed a total of 119 resected esophagi with intraepithelial neoplasias low grade (including slight or moderate dysplasias), high severe dysplasia and carcinoma in situ), microinvasive squamous (i.e., not invasive beyond the submucosa without metastases regional lymph nodes). Epithelial buds bulging into stroma were noted noninvasive lesions. The most degree histological alteration was used to characterize each case. Of cases, five low-grade, 38 high-grade, remaining 76 specimens...
PURPOSE The prognostic value of lymphocyte infiltration score (LIS) and its nearest neighbor distance to tumor cells (NNDTC) in giant cell bone (GCTB) is currently not well established. This study aims characterize LIS NNDTC examine their correlation with denosumab treatment responsiveness, clinicopathologic features, patient prognosis. METHODS Using multiplexed quantitative immunofluorescence, was evaluated 253 specimens, whereas computed using HALO software. Subsequently, we analyzed the...
Hyperlipidemia has been extensively recognized as a high-risk factor for NASH; however, clinical susceptibility to NASH is highly heterogeneous. The key controller(s) of in patients with hyperlipidemia not yet elucidated. Here, we aimed reveal the regulators and explore its role underlying mechanisms.
Abstract The population of Linxian in China has one the world's highest rates for esophageal/gastric cardia cancer, as well documented nutritional deficiencies. To determine whether dietary supplementation with a multi‐vitamin multi‐mineral preparation could reduce risk esophageal cancer and favorably influence precursor lesions, 3,318 individuals age 40‐69 cytologically determined grade I or 2 dysplasia were randomly assigned to receive either an active supplement placebo. Pills distributed...
Cavin1 is a cell membrane caveolin, with controversial function in different tumors. Meanwhile, the role of hepatocellular carcinoma (HCC) progression remains unclear. In this study, we attempted to elucidate significance HCC occurrence and progression. content was examined tissues paired adjacent normal liver by qRT-PCR IHC among 81 patients. The Cavin1-mediated regulation proliferation metastasis assessed through vitro vivo experiments. Finally, using GSEA, found out could be potential...
To the Editor: Kaposiform hemangioendothelioma (KHE) is a rare, locally invasive, vascular tumor of infants and adolescents. It has an annual incidence approximately 0.071 per 100,000 children.[1,2] KHE roughly equal gender ratio.[3] generally affects soft tissues presenting as mass lesions with associated cutaneous abnormities Kasabach-Merritt phenomenon (KMP).[4–6] locating in non-cutaneous sites (such viscera retroperitoneum) those KMP are reported to be poor prognosis due more aggressive...
The contributing factors for spondylitis after percutaneous vertebroplasty (PVP) or kyphoplasty (PKP) remain unclear. Here, we sought to investigate the affecting occurrence PVP/PKP. We also compared clinical characteristics between patients with tuberculous (TS) and nontuberculous (NTS) following vertebral augmentation. Literature searches (from January 1, 1982 October 16, 2020) using MEDLINE, EMBASE, Google Scholar Web of science databases were conducted identify eligible studies according...
Purpose This study aimed to summarize the characteristics of 100 most-cited articles on adult spinal deformity (ASD) and analyze past current research hotspots trends. Methods Literature searches (from inception 28 April 2022) using Web Science databases were conducted identify ASD-related articles. The top collected for further analysis. Meanwhile, author keywords from published in last 5 years selected Results ASD 3,354 papers. publication year ranged 1979 2017, all papers written English....
Due to the difficulty of pathological sampling, clinical differentiation between benign and malignant biliopancreatic diseases remains challenging. Endoscopic retrograde cholangiopancreatography (ERCP) is used investigate biliary diseases, enabling collection bile. This study assessed potential metabolic alterations in malignancies by exploring changes bile metabolome diagnostic analysis.
Abstract Background: The liver cyst is a common disease in hepatobiliary surgery. Most patients have no apparent symptoms and are usually diagnosed accidentally during imaging examinations. vast majority of with cysts follow benign course, very few serious complications rare reports malignant changes. Case Presentation: We present two cases that evolved into intrahepatic tumors the follow-up process. first patient had undergone fenestration drainage operation for cyst, cancer was found at...