- Acute Myeloid Leukemia Research
- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Eosinophilic Disorders and Syndromes
- Probiotics and Fermented Foods
- Lymphoma Diagnosis and Treatment
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Postharvest Quality and Shelf Life Management
- Retinoids in leukemia and cellular processes
- Meat and Animal Product Quality
- Acute Lymphoblastic Leukemia research
- Microbial Metabolites in Food Biotechnology
- Viral Infectious Diseases and Gene Expression in Insects
- Protein Hydrolysis and Bioactive Peptides
- Microbial Inactivation Methods
- Cytomegalovirus and herpesvirus research
- T-cell and Retrovirus Studies
- Advanced biosensing and bioanalysis techniques
- Plant and soil sciences
- Herpesvirus Infections and Treatments
- Animal Disease Management and Epidemiology
- Polyomavirus and related diseases
- Sensory Analysis and Statistical Methods
- Cholesterol and Lipid Metabolism
- Quinazolinone synthesis and applications
National Agricultural Technology Institute
2001-2021
National Institute of Industrial Technology
2015-2021
Sapienza University of Rome
1990-2019
Policlinico Umberto I
2017
Centro de Investigaciones Cardiovasculares
2008
Medizinische Hochschule Hannover
1990
Background The genetic characterization of chronic lymphocytic leukemia cells correlates with the behavior, progression and response to treatment disease.Design Methods Our aim was investigate role ATM gene alterations, their biological consequences value in predicting disease progression. analyzed by denaturing high performance liquid chromatography multiplex ligation probe amplification a series patients at diagnosis. results were correlated immunoglobulin mutations, cytogenetic...
Abstract We describe an outbreak of vomiting, wasting, and encephalomyelitis syndrome in piglets Argentina, caused by porcine hemagglutinating coronavirus (PHE-CoV) infection. Diagnosis was made epidemiologic factors, pathologic features, immunohistochemistry, reverse transcription–PCR, genomic sequencing. This study documents PHE-CoV infection South America.
Acute promyelocytic leukemia (FAB-M3) is a distinct entity among acute non-lymphoid leukemias (ANLL) with peculiar morphological, biological, clinical and prognostic features. An atypical form of M3 (M3v) could be confused other FAB ANLL therefore the diagnosis this variant requires ultrastructural analysis and/or cytogenetic study selective gene rearrangement studies. The immunological phenotype blast cells in 39 APL patients was studied at diagnosis. type ascertained 32 M3v 7 cases. Using...
Bovine herpesvirus-1 (BHV-1) and bovine herpesvirus-5 (BHV-5) are closely related viruses which exhibit some important differences at the genetic immunogenic levels may explain in their pathogenicity epidemiological characteristics. A multiplex polymerase chain reaction (M-PCR) was developed to detect differentiate between BHV-1 BHV-5. In this M-PCR two pairs of primers (TK1, TK2 GD1, GD2) were used same mix amplify a thymidine kinase genomic region (183 bp) one gLycoprotein D (564 The...
Abstract The study was accomplished to optimize the application of stress treatment prevent chilling injury ( CI ) in tomatoes. Four treatments were evaluated: control, heat shock applied for 24 HS 24) and 48 h 48), cold CS 24). fruits stored at 2 14C, evaluated immediately after 21 28 days storage. An additional evaluation 7 exposure 20C following storage withdrawal included induce ripening exteriorize development symptoms. Different biochemical quality attributes (color, titratable...
Cytogenetic analyses of bone marrow cells were carried out by means direct technique and short-term cultures in 25 acute promyelocytic leukaemia (APL) patients. 16 affected the hypergranular form 9 M3-variant. The t(15;17) was documented at diagnosis 15 In addition, 2 cases, which an M3 morphology a normal karyotype on preparation found diagnosis, disclosed chromosome anomaly cultured relapse, concomitance with change blast to However, consistent feature 5 patients analysed preparations only...
The occurrence of acute myeloid leukemia (AML) as a secondary tumor has been frequently reported in patients who received various chemotherapy regimens for hematologic malignancies wile the concomitant development chronic lymphoproliferative diseases (CLD) and AML previously untreated is extremely rare. We report case with an apparently spontaneous non Hodgkin low-grade lymphoma diagnosed by immunological, cytogenetical molecular analyses. In particular genetic studies allowed to identify...
An indirect enzyme-linked immunosorbent assay (ELISA) was developed for differentiation of animals infected with foot-and-mouth disease virus (FMDV) from vaccinated animals. The test based on a highly pure and concentrated preparation recombinant 3AB1 protein obtained by expression in prokaryotic system, separation sodium dodecyl sulfate–polyacrylamide gel electrophoresis, electro elution. Experimental- field-serum samples naive, vaccinated, cattle were tested anti3AB1 antibody using the...
Our objective was to evaluate the effects of providing shade and combined with evaporative cooling on production, cow activity, metabolism, hepatic gene expression late-lactation Holstein dairy cows under moderate heat-stress conditions. Forty-eight multiparous were used in a completely randomized block-design trial randomly assigned 1 3 treatments: control (CTL), without access shade; artificial (SH); (SHplus). Results analyzed using mixed procedure repeated measures. No differences...
Journal Article Ablative chemotherapy followed by peripheral blood stem cell reinfusion for chronic myelogenous leukemia in phase Get access G. Meloni, Meloni Hematology, Dept. of Human Biopathology, University "La Sapienza", Rome, Italy Search other works this author on: Oxford Academic Google Scholar R. M. Pinto, Pinto P. De Fabritiis, Fabritiis Nanni, Nanni Mancini, Mancini A. F. Cardillo, Cardillo Simone, Simone D. Diverio, Diverio Vignetti, Vignetti Mandelli The International Of Cell...