Susan Marquez
A5047250842- Diet and metabolism studies
- Cardiac Ischemia and Reperfusion
- Organ Transplantation Techniques and Outcomes
- 3D Printing in Biomedical Research
- Clinical Nutrition and Gastroenterology
- Innovative Microfluidic and Catalytic Techniques Innovation
- Hydrogen's biological and therapeutic effects
- Organ Donation and Transplantation
- Microfluidic and Capillary Electrophoresis Applications
- Reproductive tract infections research
- Mitochondrial Function and Pathology
- Mass Spectrometry Techniques and Applications
- Erythrocyte Function and Pathophysiology
- Neuroscience and Neural Engineering
- Blood disorders and treatments
- Preterm Birth and Chorioamnionitis
- Anatomy and Medical Technology
- Hematopoietic Stem Cell Transplantation
- Genetic and Kidney Cyst Diseases
- Renal and related cancers
- Reproductive System and Pregnancy
- Renal Diseases and Glomerulopathies
Inspire
2023-2024
Harvard University
2020-2024
Boston University
2023
Despite remarkable advances in Organ-on-a-chip (Organ Chip) microfluidic culture technology, recreating tissue-relevant physiological conditions, such as the region-specific oxygen concentrations, remains a formidable technical challenge, and analysis of tissue functions is commonly carried out using one analytical technique at time. Here, we describe two-channel Organ Chip devices fabricated from polydimethylsiloxane gas impermeable polycarbonate materials that are integrated with multiple...
Drugs that induce reversible slowing of metabolic and physiological processes would have great value for organ preservation, especially organs with high susceptibility to hypoxia-reperfusion injury, such as the heart. Using whole-organism screening metabolism, mobility, development in Xenopus, we identified an existing drug, SNC80, rapidly reversibly slows biochemical activities while preserving cell tissue viability. Although SNC80 was developed a delta opioid receptor activator, discovered...
Drugs that induce reversible slowing of metabolic and physiological processes would have great value for organ preservation, especially organs with high susceptibility to hypoxia-reperfusion injury, such as the heart. Using whole-organism screening metabolism, mobility, development in Xenopus , we identified an existing drug, SNC80, rapidly reversibly slows biochemical activities while preserving cell tissue viability. Although SNC80 was developed a delta opioid receptor activator,...
Drugs that induce reversible slowing of metabolic and physiological processes would have great value for organ preservation, especially organs with high susceptibility to hypoxia-reperfusion injury, such as the heart. Using whole-organism screening metabolism, mobility, development in Xenopus , we identified an existing drug, SNC80, rapidly reversibly slows biochemical activities while preserving cell tissue viability. Although SNC80 was developed a delta opioid receptor activator,...
Drugs that induce reversible slowing of metabolic and physiological processes would have great value for organ preservation, especially organs with high susceptibility to hypoxia-reperfusion injury, such as the heart. Using whole-organism screening metabolism, mobility, development in Xenopus , we identified an existing drug, SNC80, rapidly reversibly slows biochemical activities while preserving cell tissue viability. Although SNC80 was developed a delta opioid receptor activator,...
ABSTRACT Drugs that induce reversible slowing of metabolic and physiological processes would have great value for organ preservation, especially organs with high susceptibility to hypoxia-reperfusion injury, such as the heart. Using whole-organism screening metabolism, mobility, development in Xenopus , we identified an existing drug, SNC80, rapidly reversibly slows biochemical activities while preserving cell tissue viability. Although SNC80 was developed a delta opioid receptor activator,...
Abstract Study question What is the underlying cause of infertility associated with bacterial vaginosis (BV)? Summary answer We provide first evidence to suggest that BV-associated could be result sperm dysfunction induced by exposure poor cervical microbiome. known already Infertility a global health concern, impacting 186 million individuals worldwide. In 25% infertile couples remains unexplained. The complex interactions between host mucosal epithelium, microbiome, and other...