A5029994416- Congenital Heart Disease Studies
- Cardiac Arrhythmias and Treatments
- Cardiac pacing and defibrillation studies
- Cardiac Valve Diseases and Treatments
- Cardiac and Coronary Surgery Techniques
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Syncope and Autonomic Disorders
- Traumatic Brain Injury Research
- Esophageal and GI Pathology
- Anatomy and Medical Technology
- Cardiac Arrest and Resuscitation
- Infective Endocarditis Diagnosis and Management
- Neuroscience and Neural Engineering
- Genetic Neurodegenerative Diseases
- Pulmonary Hypertension Research and Treatments
- Neurological disorders and treatments
- Health, psychology, and well-being
- Cardiac Structural Anomalies and Repair
- Maternal and Neonatal Healthcare
- Cardiovascular Effects of Exercise
- Diabetes Management and Research
- Disaster Response and Management
- Botulinum Toxin and Related Neurological Disorders
- Diabetes and associated disorders
Harvard University
2020-2024
University of Arizona
2014-2024
Boston Children's Hospital
2018-2024
Boston Children's Museum
2022
Abstract Background It is not known whether prisoners of war (POWs) are more likely to develop dementia independently the effects posttraumatic stress disorder (PTSD). Methods We performed a retrospective cohort study in 182,879 U.S. veterans age 55 years and older, examined associations between POW status PTSD at baseline (October 1, 2000–September 30, 2003), incident during follow‐up 2003–September 2012). Results A total 484 (0.3%) reported being POWs, whom 150 (31.0%) also had PTSD. After...
ABSTRACT Background Atrial fibrillation and atrial flutter are relatively rare in young people the incidence of thromboembolic complications is unknown. These issues contribute to limited utility present guidelines regarding anticoagulation this population. Objective To report number a cohort pediatric adult patients presenting with (AFib) or (AFl) while also assessing practice multicenter these arrhythmias. Methods Multicenter, retrospective aged < 25 years old who presented between 2000...
Sudden cardiac arrest is a rare but devastating cause of death in young adults. Electrocardiograms may detect many causes sudden arrest, are not routinely included pre-athletic screening the United States America partly because high rates false-positive interpretation. To improve electrocardiogram specificity for identifying conditions associated with an expert panel developed refined criteria known as Seattle Criteria. Ours first study to compare standard Criteria 11- 13-year-olds. In...
Objective This study evaluates the ability of experienced pediatric electrophysiologists (EPs) to reliably classify incomplete right bundle branch block (IRBBB) and assesses its clinical utility as an isolated ECG finding in a group healthy outpatient children without prior cardiac evaluation. Design We performed retrospective analysis all electrocardiographic echocardiographic records at Boston Children's Hospital between January 1, 2005, December 31, 2014. Echocardiographic diagnoses were...
Abstract Introduction Guidelines recommend trans‐esophageal echocardiography (TEE) for patients with atrial fibrillation (AF) or flutter (AFL) >48 h, due to risk of intracardiac thrombus formation. With growing evidence that AFL in adults structurally normal hearts has less thrombogenic potential compared AF, and the need TEE questioned, we prevalence detected by pediatric congenital heart disease (CHD) presenting AF AFL. Methods/Results Single‐center, cross‐sectional analysis unique...
Type 1 myotonic dystrophy (DM1) is a neuromuscular disorder of multiple organ systems with important electrophysiologic (EP) manifestations, leading to cumulative incidence sudden death 6.6%. Due genetic anticipation, there pediatric subset this patient population. However, most EP research on DM1 patients has been in adults, making cardiac care for difficult and directed by adult guidelines which often leads cardiovascular implantable electronic device (CIED) implants. We sought investigate...
Background: G6PD deficiency classically presents with hemolytic anemia, but associations have been described atherogenesis and coronary artery disease. There are limited data that also suggest a link between the development of congenital heart disease (CHD). Hypothesis: We hypothesize higher incidence CHD among individuals as well worse hospital outcomes for those deficiency. Methods: reviewed Vizient® Clinical Data Base (a national, administrative database) from 10/2019-3/2024 admissions...
Introduction: Individuals with congenital heart disease (CHD) have increased risk of immune suppression and elevated inflammatory markers in response to abnormal cardiac physiology. This pathologic milieu may put them at for developing autoimmune (AID). Hypothesis: We hypothesized a higher incidence AID patients CHD. Methods: conducted retrospective review the Vizient® Clinical Data Base (a national, administrative database) from 10/2019–12/2023 admissions aged 1-25 years ICD-10 codes AID,...
Background: Advancements in life-saving treatment for patients with moderate and severe congenital heart disease (CHD) has led to the exponential growth of a novel population individuals CHD who previously did not survive beyond infancy. Little is known about impact other medical comorbidities on overall health these individuals. We sought assess effect comorbid Type 1 diabetes (T1DM) hospitalized CHD. Hypothesis: hypothesized that had T1DM would have worse hospital outcomes than those...
Background: Improved congenital heart disease (CHD) care allows >90% of patients to live into adulthood, but young adult CHD are challenged by managing their own as well the risk other comorbidities that may increase healthcare resource utilization. There is limited data on hospitalizations adolescents with CHD, specifically during transition from pediatric care. Hypothesis: We hypothesized age care, utilization resources will increase. Methods: conducted a retrospective review Vizient®...
Patients with congenital heart disease (CHD) may require stent placement for various vascular stenoses. Multiple stents are used "off-label" patients CHD. There is a need accessible, modifiable and customizable This study aims to provide proof of concept patient-specific 3D printed metal Five hearts CHD stenoses were identified from our anonymized model database printed. Custom designed using SolidWorks Meshmixer steel the Ultimaker S5 Pro printer Metal Expansion Kit. The models digitally...
Abstract Introduction Accessory atrioventricular pathways (APs) may mediate reciprocating tachycardia and, in some cases, have the potential to conduct atrial rapidly, which can be life threatening. While catheter ablation curative, of right free wall APs is associated with a high rate recurrence, likely secondary reduced stability along groove. We sought identify characteristics lower recurrence and hypothesized lesions placed on ventricular side groove using retroflexed approach would...