A5032342893- High voltage insulation and dielectric phenomena
- Oral microbiology and periodontitis research
- Recycling and Waste Management Techniques
- Innovation Policy and R&D
- Aerosol Filtration and Electrostatic Precipitation
- Advanced Sensor and Energy Harvesting Materials
- Lightning and Electromagnetic Phenomena
- Power Transformer Diagnostics and Insulation
- Electrohydrodynamics and Fluid Dynamics
- Surface Modification and Superhydrophobicity
- Oral and gingival health research
- Periodontal Regeneration and Treatments
- Advanced Glycation End Products research
- TGF-β signaling in diseases
- Cell Adhesion Molecules Research
- Cancer-related gene regulation
- Dental Radiography and Imaging
- Oral Health Pathology and Treatment
- Endodontics and Root Canal Treatments
- Salivary Gland Disorders and Functions
- Bone health and treatments
- Advanced Fiber Optic Sensors
- Immune Response and Inflammation
- Cellular Mechanics and Interactions
- Catalytic Processes in Materials Science
Fuji Electric (Japan)
2014-2024
Kobe Tokiwa University
2021-2024
Okayama University Hospital
2019-2023
Okayama University
2007-2022
Kyushu University
2018-2021
University of Hyogo
2019-2020
Niigata University of Management
2019-2020
Mitsubishi Electric (Japan)
2019-2020
Shibaura Institute of Technology
2019-2020
Tokyo City University
2020
Periapical periodontitis results from pulpal infection leading to necrosis and resorption of periapical bone. The current treatment is root canal therapy, which attempts eliminate necrotic tissue. But, in some cases inflammation doesn't resolve even after treatment. Resolvins are part a large family specialized pro-resolving lipid mediators that actively resolves signalling via specific receptors. Resolvin D2 (RvD2), metabolite docosahexaenoic acid (DHA), was tested as an intracanal...
AlN substrate is widely used along with silicone gel to encapsulate power electronic circuits. It known that the weakness of insulation system surface discharges propagating at gel-substrate interface. In this research, nature in gel, on various substrates was investigated. The results are as follows: maximum stopping length cavities more than twice other substrates, and light emission due different from substrates; for substrate, tip cavity emitted while part did not emit light, all path...
Silicone gel is widely used to encapsulate power electronic modules. The weakness of the electrical insulation surface discharges initiated at gel-substrate-electrode triple junction and subsequent formation cavities; so called trees. propagation characteristics cavities under high frequency fast rise time voltages, which are typical waveforms formed in modules, have not been fully understood. Thus, this research, influence frequency, time, polarity on treeing repetitive voltage impulses...
ABSTRACT High mobility group box 1 (HMGB1) is a non-histone DNA-binding protein that secreted into the extracellular milieu in response to inflammatory stimuli. The HMGB1 mediates various diseases, including periodontitis; however, underlying mechanisms of HMGB1-induced periodontal inflammation are not completely understood. Here, we examined whether anti-HMGB1 neutralizing antibody inhibits progression and investigated molecular pathology vitro vivo. In analysis indicated HMGB1,...
Silicone gel is widely used to encapsulate power electronic circuits. It known that the weakness of this insulation system surface discharges between and substrate. These give rise growth cavities in gel, which may lead eventual failure insulation. Despite fact, has not yet been studied enough. In order clarify nature streamers cavity relation streamer propagation charge accumulation at interface cavity, apparent charge, light emission, motion cavities, dynamic potential distribution...
Abstract Background Basic fibroblast growth factor (bFGF) has been applied for periodontal regeneration. However, the application depends on bone defect morphology because bFGF diffuses rapidly from sites. In a previous study, collagen‐binding (CB‐bFGF) shown to enhance formation by collagen‐anchoring in orthopedic field. The aim of this study is demonstrate efficacy CB‐bFGF with collagen scaffolds regeneration horizontal defect. Methods Cell proliferation activity and binding was confirmed...
During periodontal regeneration, inhibition of gingival downgrowth is necessary to promote migration mesenchymal cells into the defects. Transforming growth factor (TGF)-β a pleiotropic cytokine that has numerous cell functions, including regulation epithelial growth. Recent studies have shown Smad2, downstream transcription TGF-β, plays crucial roles in wound healing epithelia. Therefore, we investigated effects Smad2 overexpression on re-epithelialization wounds. Transgenic mice...
Silicone gel is used to encapsulate power electronic circuits. The weakness of this insulation system surface discharges which degrade silicone gel. In paper, various features discharge in are evaluated by analyzing the motion cavities induced and measuring dynamic potential distributions results indicated that charges accumulated at cavity contribute retaining path. Temporal response explained using a classical capacitance model.
Abstract High mobility group box 1 (HMGB1) is a non‐histone DNA‐binding protein that secreted into the extracellular milieu in response to inflammatory stimuli. The HMGB1 has been suggested mediate various diseases. However, it still unknown whether involved healing process tooth extraction socket, tissue containing gingival epithelium, and alveolar bone exposed oral bacteria. In this study, we constructed murine model with anti‐HMGB1 neutralization antibody administration observed sockets...
Abstract The ozone‐zero phenomenon named by the authors of this paper is investigated emission spectroscopy and temporal variations ozone concentrations. measurements concentrations are performed monitors placed at outlets two generators. generators operated independently; however a gas flow system connected in series through direction. Ozone‐zero means that concentration outlet generator during phenomenon, almost zero when using dielectric barrier discharge (DBD) pure oxygen as feed gas. It...
Quantitative information on the charge and stress profile during partial discharges (PDs) is required in order to discuss clarify process of electrical degradation solids. Such PDs cause cavities grow. Therefore, we have proposed a procedure for analysing within cavities, based motion observation viscoelastic material. The was applied surface silicone gel. Spherical sub-cavities (voids) which form along were analysed. temporal response calculated exerted void depends location void: whether...
The medial epithelial seam (MES) between the palatal shelves degrades during fusion to achieve confluence of mesenchyme. Cellular mechanisms underlying degradation MES have been proposed, such as apoptosis, epithelial-mesenchymal transition (EMT) and migration edge epithelia (MEE). Extracellular matrix components shown play an important role in EMT many model systems. Periostin (also known osteoblast-specific factor-2) is a secreted mesenchymal extracellular component that affects ability...
Background and Objective Spatiotemporal inhibition of apical migration proliferation gingival epithelium are significant factors involved in periodontal regeneration. Transforming growth factor β ( TGF ‐β) is important multiple aspects wound healing, S mad2, a downstream transcription ‐β, has an inhibitory effect on re‐epithelialization during healing. Therefore, we investigated the effects status, intra/extracellular signaling regulated by mad2 overexpression epithelial cells. Material...
Silicone gel is widely used to encapsulate power electronic circuits. It well known that surface discharge in the module one of weakest points insulation. These discharges cause growth cavity silicone gel. We have observed dynamics order investigate degradation process. The results indicated streamers propagate through gaseous phase filamentary channels from electrode and reaches tip cavity, leaves charges until next occurs. Moreover it was revealed propagation caused by positive discharges....
Key Clinical Message Oral bacteria cause infective endocarditis ( IE ), so severe periodontitis is thought to be high risk for . We suggest the identification of high‐risk patients by an IgG antibody titer test against periodontal might become common screening test.