Xiaoying Yuan

ORCID: 0000-0003-1210-5654
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Research Areas
  • Pregnancy and preeclampsia studies
  • Advanced oxidation water treatment
  • Advanced Photocatalysis Techniques
  • Birth, Development, and Health
  • Gestational Diabetes Research and Management
  • Extracellular vesicles in disease
  • Cancer Genomics and Diagnostics
  • TiO2 Photocatalysis and Solar Cells
  • Chemical Synthesis and Characterization
  • PARP inhibition in cancer therapy
  • DNA Repair Mechanisms
  • Gut microbiota and health
  • Radioactive element chemistry and processing
  • Systemic Sclerosis and Related Diseases
  • MicroRNA in disease regulation
  • Extraction and Separation Processes
  • Liver Disease Diagnosis and Treatment
  • Lipid metabolism and disorders
  • Gastrointestinal motility and disorders
  • Bladder and Urothelial Cancer Treatments
  • Chronic Kidney Disease and Diabetes
  • Tryptophan and brain disorders
  • Circular RNAs in diseases
  • Cardiovascular Disease and Adiposity
  • Arsenic contamination and mitigation

Fuzhou University
2024-2025

Dalian Medical University
2023-2025

Gannan Medical University
2025

Hangzhou DAC Biotech (China)
2022-2024

Affiliated Zhongshan Hospital of Dalian University
2023

First Affiliated Hospital of Gannan Medical University
2023

Guangdong Provincial People's Hospital
2013

Large-scale extraction of uranium from seawater (UES) is considered to be an important way solve the nuclear fuel shortage, and development highly efficient selective adsorbents a key factor in realizing UES. In this work, Schiff base-conjugated amidoxime modificated porous organic polymers (OPA-PPA-AO) were synthesized by aldehyde-amine condensation hydroxylamine reactions for adsorption uranium. OPA-PPA-AO has excellent selectivity high capacity, with 53 times capacity vanadium, maximal...

10.2139/ssrn.5084576 preprint EN 2025-01-01

Background Prostate cancer (PCa) in the transition zone (TZ) is uncommon and often poses challenges for early diagnosis, but its genomic determinants therapeutic vulnerabilities remain poorly characterized. Methods Tumor mutational landscape was characterized nine patients with TZ PCa, identifying somatic variants through whole-exome sequencing (WES). Novel candidate relevant to driver gene were selected using rare-variant burden analysis. Kaplan-Meier curves log-rank testing Cox regression...

10.3389/fendo.2025.1568665 article EN cc-by Frontiers in Endocrinology 2025-04-14

Abstract Background Interindividual variation characterizes the relief experienced by constipation-predominant irritable bowel syndrome (IBS-C) patients following linaclotide treatment. Complex bidirectional interactions occur between gut microbiota and various clinical drugs. To date, no established evidence has elucidated linaclotide. We aimed to explore impact of on identify critical bacterial genera that might participate in efficacy. Methods IBS-C were administered a daily dose 290 µg...

10.1186/s12967-024-04898-1 article EN cc-by Journal of Translational Medicine 2024-01-23

Objective: To analyze the correlation between urinary albumin/creatinine ratio (ACR) and 24-hour microalbumin (UMA) evaluate predictive value of ARC for early diabetic nephropathy. Methods: A total 368 patients with type 2 diabetes mellitus were retrospectively collected. Early nephropathy was defined as 24h UMA 30~<300 mg/24h. The ACR 24hUMA, area under receiver operating characteristic (ROC) curve in diagnosis calculated. Gender, age, course disease, fasting venous blood glucose,...

10.3760/cma.j.issn.0578-1426.2019.05.009 article EN PubMed 2019-05-01

Background: The association between misfolded proteins presented in the urine of pregnant women and pregnancy outcomes associated with early-onset pre-eclampsia (PE) remains unclear. This study aimed to investigate this examine predictive value urinary congophilia prognostication patient group Chinese population. Materials Methods: included 1,397 patients, which 46, 147, 8 patients had gestational hypertension, PE, chronic respectively, 1,196 were healthy controls undergoing CapCord test for...

10.3389/fmed.2021.700157 article EN cc-by Frontiers in Medicine 2021-08-02

Background Preeclampsia (PE) is one of the most common hypertensive diseases, affecting 2%-8% all pregnancies. The high maternal and fetal mortality rates PE are due to a lack early identification affected pregnant women that would have led closer monitoring care. Recent data suggest misfolded proteins might be promising biomarker for prediction, which can detected in urine samples according their congophilia (aggregated) characteristic. Objective main purpose this trial evaluate value...

10.2196/54026 article EN cc-by JMIR Research Protocols 2024-03-21

The photocatalytic activation of the persulfate process has been considered a promising water treatment technology because generation highly oxidative sulfate radical (•SO4−) for organic pollutant mineralization. However, sluggish diffusion •SO4− from catalyst surface into bulk solution severely limits availability and utilization. Herein, we presented defective carbon nitride (DCN) as efficient peroxymonosulfate-activation coupling nonradical aggregation-radical tailored electronic...

10.2139/ssrn.4836579 preprint EN 2024-01-01

Objective To explore the effect of clinical pathway on health education patients with nasopharyngeal carcinoma,so as to establish optimal model education.Methods Through development nursing pathway,totals 80 cases were randomly divided into control group (n =40)and experimental =46).Patients in received routine education,while according pathway.Then,patients' knowledge and satisfaction quality was compared between two groups.Results The compliance rate master (97.83% vs 45.00%) degree...

10.3760/cma.j.issn.1674-2907.2013.15.019 article EN Zhonghua xiandai huli zazhi 2013-05-26

<sec> <title>BACKGROUND</title> Preeclampsia (PE) is one of the most common hypertensive diseases, affecting 2%-8% all pregnancies. The high maternal and fetal mortality rates PE are due to a lack early identification affected pregnant women that would have led closer monitoring care. Recent data suggest misfolded proteins might be promising biomarker for prediction, which can detected in urine samples according their congophilia (aggregated) characteristic. </sec> <title>OBJECTIVE</title>...

10.2196/preprints.54026 preprint EN 2023-11-08

Objective To evaluate the effect of Danqi Yishen decoction on diabetes mellitus(DM) and its influence proteinuria. Methods 150 DM patients were randomly selected, they divided into two groups according to digital table, 75 cases in each group.The control group was given western medicine, study treated by decoction.The treatment efficacy, blood serum creatinine(Cr), 24h urine protein, urea nitrogen(BUN) fasting glucose(FBG) before after compared between groups. Results The total...

10.3760/cma.j.issn.1008-6706.2018.09.017 article EN Zhongguo jiceng yiyao 2018-05-01

Background: Aggregates of misfolded proteins, which previously were shown to be related preeclampsia, may used as diagnostic marker by testing patients' urine. We developed an easy-to-perform POCT (point care test) method for detecting urinary proteins we termed "Misfolded Protein Test", and validated its utility in a large clinically relevant cohort.

10.2139/ssrn.3269602 article EN SSRN Electronic Journal 2018-01-01
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