A5040953200- Phytochemistry and biological activities of Ficus species
- Essential Oils and Antimicrobial Activity
- Natural Antidiabetic Agents Studies
- Drug-Induced Hepatotoxicity and Protection
- Phytochemistry and Biological Activities
- Pacific and Southeast Asian Studies
- Postharvest Quality and Shelf Life Management
- Plant Pathogens and Fungal Diseases
- Plant Pathogens and Resistance
- RNA regulation and disease
- Telomeres, Telomerase, and Senescence
- Immunodeficiency and Autoimmune Disorders
- HIV/AIDS oral health manifestations
- Powdery Mildew Fungal Diseases
- Ginger and Zingiberaceae research
- Date Palm Research Studies
- Cancer-related molecular mechanisms research
- Infectious Diseases and Tuberculosis
- Pharmacovigilance and Adverse Drug Reactions
- Ginkgo biloba and Cashew Applications
- Proteins in Food Systems
- HIV, Drug Use, Sexual Risk
- Medicinal Plants and Neuroprotection
- Yersinia bacterium, plague, ectoparasites research
- Cocoa and Sweet Potato Agronomy
Université de Yaoundé I
2016-2024
Port Moresby General Hospital
2024
Burnet Institute
2024
University of Maroua
2024
Université d'Avignon et des Pays de Vaucluse
2017
University of Bamenda
2017
International Institute of Tropical Agriculture
2017
The non-steroidal anti-inflammatory drugs (NSAIDs) is a drug class that groups together provide analgesic (pain-killing) and antipyretic (fever-reducing) effects, and, in higher doses, effects.The properties acts by inhibiting two recognized isoenzymes of prostaglandin G/H synthase also known as cycl-oxygenase (COX), which are COX 1 2.The pharmacodynamic action these mostly mediated inhibition COX2, while the adverse reactions largely due to COX1 inhibition..The NSAID selectively COX2 were...
Introduction: Contract Research Organizations (CROs), Clinical Centers/Networks and private research institutions play an important role in the clinical process, especially drug discovery development process. They act as essential partners for pharmaceutical delivery/development biotech companies. Over last few decades, demand outsourcing of by companies has increased, with market CRO institutional services growing significantly. This trend been driven a need increased productivity...
The work focuses on evaluating the antioxidant capacity and studying anticonvulsant properties of bark Hymencardia acida (Euphorbiaceae), which is a tropical African plant traditionally used in Centre Region Cameroon treatment many diseases such as migraines, diarrhoea, wounds, stomach ache influenza. various tests carried out have highlighted high content these plants. results activity showed that: decoction antagonized convulsions induced by 100% pentylenetetrazole at doses 22.5, 45 90...
HLA allelic variation has been well studied and documented in many parts of the world. However, African populations have relatively under‐represented studies variation. We characterized from 489 individuals belonging to 13 ethnically diverse rural communities countries Botswana, Cameroon, Ethiopia, Tanzania, known practice traditional subsistence lifestyles using next generation sequencing (Illumina) long‐reads Oxford Nanopore Technologies. identified 342 distinct alleles among 11 targeted...
Globally the taro leaf blight (Phytophthora colocasiae) disease causes between 50 to 70% yield loss. Four landraces were planted in three agroecological zones of Cameroon; Western Highlands (Bambui), Mono-Modal Humid Forest (Ekona), and Bimodal (Nkolbisson) evaluated for severity four successive growing seasons March July, 2018 2019. Different concentrations copper oxide (600 g)–Metalaxyl (120 g) fungicide applied control before during plant growth. Results showed that, all field sites,...
Background and objective: The research on nutritional health-benefiting compounds has increased in leafy vegetables such as Ficus dicranostyla.The current study was conducted to evaluate the effect of sieved-based fractionation nutrient content, polyphenolic components, antioxidant activities dicranostyla leaves powder. Methods: Dried powder sieved at three size classes (<125 µm, between 250 125µm, ≥ µm) unsieved produced characterized for proximate composition, minerals, total phenolic,...
<sec><title>SETTING</title>Multidrug-resistant/rifampicin-resistant TB (MDR/RR-TB) is now endemic in the National Capital District (NCD), Papua New Guinea. Loss to follow-up (LTFU) a challenge.</sec><sec><title>OBJECTIVE</title>To evaluate and identify risk factors for LTFU, including pre-treatment adults with MDR/RR-TB at Port Moresby General Hospital (PMGH).</sec><sec><title>DESIGN</title>A retrospective analysis of...
The knowledge gaps in the nutritional composition and quality of traditionally textured plant-based products eaten as meat is affecting global acceptance despite acclaimed health, environmental, ethical, religious, social benefits. This paper aimed to prepare evaluate Nyam ngub for potential valorization vulgarization. Standard methods were used determine chemical protein. Protein fractions estimate solubility individual amino acids analysed with rapid acid analyser. Nutrient bio...
Ficus dicranostyla is a plant from the Moraceae family commonly used in African countries for its nutritional value and believed medicinal properties. Its antioxidant vitro capacity richness phenolic compounds have been previously demonstrated. This work aimed at evaluating hepatoprotective vivo activities of different granulometric fractions F. leaves against carbon tetrachloride-induced hepatotoxicity rats. Powdery (<125, 250-125, ≥250 μm), unsieved powder, obtained were water-dissolved...
Effets inhibiteurs de l'huile graines neem sur des microorganismes d'altération et pathogènes la mangue 4 ème gamme.
Ficus thonningii (Blume) is considered as a herbal plant with well documented biological activity in the management of several diseases tropics. However, there gap information on its safety and proof efficacy evidence-based medicine. The objective this study was to characterize bioactive metabolites hydro-ethanolic extract stem bark Ficus. vivo evaluation systemic exposure metabolite. Phytochemical screening done using standard extraction techniques, test according methods adopted from...
Ficus thonningii (Blume) is a medicinal plant whose biological activity has been demonstrated in the management of peptic ulcers. Unfortunately, little scientific data exists on its toxicity. This why we studied acute and subacute oral toxicity profile hydro-ethanolic extract bark F. systemic exposure bioactive components plant.Acute was assessed by administering single dose 2000 mg/kg to 5-week-old rats observed for 14 days. The study performed 6-week-old rats. Animals were orally treated...
Mallotus oppositifolium. Müll. Arg (Euphorbiaceae) is commonly used in the Center Region of Cameroon against diarrheal syndromes and joint pains. In order to provide a scientific basis for its use traditional treatment diarrhea, we proposed evaluate effects aqueous extracts leaves this plant on characteristic patterns diarrhea. The ethnopharmacological approach was carried out Gouifé village Bafia (Cameroon) by observing therapeutic practices interview 5 therapists 11 their patients about...
Effets inhibiteurs de l'huile graines neem sur des microorganismes d'altération et pathogènes la mangue 4 ème gamme.
<h3>Introduction</h3> Hepatotoxicity and anaemia are relevant adverse effects of ART can cause interruption therapy death. However, there is dearth information on hepatotoxicity co-morbidity especially in rural areas. The aim the study was to identify prevalence Anaemia among HIV treated patients. <h3>Methods</h3> A total 150 drug naïve patients visiting day hospital Fundong District Hospital were recruited into from January-March 2015 follow up for 18 months. Baseline months levels CD4...
Pharmacovigilance has become an important component of drug development phytomedicine in sub Saharan Africa.The term pharmacovigilance means all scientific and data gathering activities relating to the detection, assessment, understanding adverse events.These are undertaken with goal identifying events understanding, their nature, frequency, potential risk factors.In developing countries there is a gap information on outcome reaction most approved drugs market.This study was therefore...