A5071130048- RNA modifications and cancer
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Lung Cancer Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Cancer-related Molecular Pathways
- Mycobacterium research and diagnosis
- Pulmonary Hypertension Research and Treatments
- IL-33, ST2, and ILC Pathways
- Asthma and respiratory diseases
- Kruppel-like factors research
- RNA Research and Splicing
- Extracellular vesicles in disease
First Affiliated Hospital of Nanchang University
2018-2025
Nanchang University
2018-2025
First Affiliated Hospital of Jiangxi Medical College
2024
Abstract Idiopathic pulmonary fibrosis (IPF), a progressive and fatal lung disease, usually leads to an irreversible distortion of the structure. The functional roles bone marrow‐derived mesenchymal stem cells (BMSC)‐secreted extracellular vesicles (EVs) in fibroblasts have been implicated, yet their actions treatment IPF are not fully understood. This study investigated BMSC‐derived EVs expressing miR‐29b‐3p treatment. derived from BMSCs were successfully isolated could be internalized by...
Chemoresistance is one of the most important biological elements affecting progression and prognosis cancer. Long non‑coding RNAs (lncRNAs) are regulators aberrantly expressed in various types cancer humans, including non‑small cell lung (NSCLC). The present study aimed to investigate effect lncRNAs on NSCLC resistance chemotherapy. relative expression level epidermal growth factor receptor antisense RNA 1 (EGFR‑AS1) was quantified by reverse transcription-quantitative polymerase chain...
Abstract Idiopathic pulmonary fibrosis (IPF) is a condition that results in the progressive deterioration of lung function with poor prognosis. The current study aimed at exploring how microRNA‐448 (miR‐448) targeting ABCC3 affects fibroblast proliferation, apoptosis, and collagen synthesis mice IPF via Jun N‐terminal kinase (JNK) signaling pathway. Bioinformatics dual‐luciferase polymerase chain reaction were used to predict relationship miR‐448 ABCC3. expression was detected tissues. Using...