Shuyun Chen

ORCID: 0000-0002-5544-0121
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About
Contact & Profiles
Research Areas
  • Air Quality and Health Impacts
  • Gestational Diabetes Research and Management
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Child Nutrition and Feeding Issues
  • Energy and Environment Impacts
  • Atmospheric chemistry and aerosols
  • Pregnancy and preeclampsia studies
  • Traditional Chinese Medicine Analysis
  • Intestinal Malrotation and Obstruction Disorders
  • Bariatric Surgery and Outcomes
  • Mercury impact and mitigation studies
  • Neurogenetic and Muscular Disorders Research
  • Diabetes Management and Research
  • Pharmacological Effects and Toxicity Studies
  • Child Nutrition and Water Access
  • Plant Physiology and Cultivation Studies
  • Peripheral Nerve Disorders
  • Physical Activity and Health
  • Infectious Encephalopathies and Encephalitis
  • Congenital gastrointestinal and neural anomalies
  • Gastrointestinal disorders and treatments
  • Adolescent and Pediatric Healthcare
  • Pregnancy and Medication Impact
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Enhanced Recovery After Surgery

Karolinska Institutet
2020-2024

Guangzhou University of Chinese Medicine
2024

Nanchang University
2020-2024

First Affiliated Hospital of Jiangxi Medical College
2024

First Affiliated Hospital of Nanchang University
2020-2022

Stockholm University
2021

State Key Laboratory of Respiratory Disease
2014-2020

First Affiliated Hospital of Guangzhou Medical University
2020

Guangzhou Medical University
2014-2020

Shanghai University of Medicine and Health Sciences
2020

With the increase of motor vehicles, ambient air pollution related to traffic exhaust has become an important environmental issue in China. Because their fast growth and development, children are more susceptible exposure. Many chemicals from exhaust, such as carbon monoxide, nitrogen dioxide, lead, have been reported show adverse effects on neurobehavioral functions. Several studies China suggested that might affect functions adults who occupational However, few data function children.The...

10.1289/ehp.0800023 article EN public-domain Environmental Health Perspectives 2009-05-11

Background Biomass smoke is associated with the risk of chronic obstructive pulmonary disease (COPD), but few studies have elaborated approaches to reduce COPD from biomass burning. The purpose this study was determine whether improved cooking fuels and ventilation effects on function incidence COPD. Methods Findings A 9-y prospective cohort conducted among 996 eligible participants aged at least 40 y November 1, 2002, through 30, 2011, in 12 villages southern China. Interventions were...

10.1371/journal.pmed.1001621 article EN cc-by PLoS Medicine 2014-03-25

Maternal diabetes has been associated with a risk of neurodevelopmental disorders (NDDs) in offspring, though the common co-occurrence autism spectrum (ASD), attention-deficit/hyperactivity disorder (ADHD) and intellectual disability (ID) is rarely considered, nor potential for confounding by shared familial factors (e.g. genetics).This population-based cohort study used data from Psychiatry Sweden, linkage Swedish national registers, to follow 2 369 680 individuals born 1987 2010. We...

10.1093/ije/dyaa212 article EN cc-by-nc-nd International Journal of Epidemiology 2020-10-06

Abstract Idiopathic pulmonary fibrosis (IPF), a progressive and fatal lung disease, usually leads to an irreversible distortion of the structure. The functional roles bone marrow‐derived mesenchymal stem cells (BMSC)‐secreted extracellular vesicles (EVs) in fibroblasts have been implicated, yet their actions treatment IPF are not fully understood. This study investigated BMSC‐derived EVs expressing miR‐29b‐3p treatment. derived from BMSCs were successfully isolated could be internalized by...

10.1002/jcp.29706 article EN Journal of Cellular Physiology 2020-06-17

Background Intrahepatic cholestasis of pregnancy (ICP) is the most common obstetric liver disorder and associated with an increased risk iatrogenic preterm birth adverse infant outcomes. Hence, there are several plausible pathways through which ICP could affect offspring neurodevelopment. However, to best our knowledge, no studies have investigated these associations. Thus, we aimed determine whether neurodevelopmental conditions. Methods findings In this Swedish register-based cohort study,...

10.1371/journal.pmed.1004331 article EN cc-by PLoS Medicine 2024-01-16

Abstract Background Subjective and social well-being, avoiding sedentary behavior (SB), engaging in physical activity (PA) are important factors for health older adults, but the extent to which they related each other remains unclear. We aimed investigate these correlations, whether differ by age. Method A cross-sectional study was carried out 595 people aged 66 years older, from Swedish National on Aging Care Kungsholmen. well-being (life satisfaction, positive negative affect, connections,...

10.1093/gerona/glab065 article EN cc-by-nc The Journals of Gerontology Series A 2021-03-01

Abstract Background Previous studies have suggested that gestational weight gain (GWG) outside an optimal range increases the risks of neurodevelopmental disorders (NDDs) in offspring including autism spectrum disorder (ASD), intellectual disability (ID), and attention deficit/hyperactivity (ADHD). The sequential development fetal brain suggests its vulnerability may vary depending on timing exposure. Therefore, we aimed to investigate associations not only age-standardized total GWG (GWG z...

10.1186/s12916-023-02799-6 article EN cc-by BMC Medicine 2023-03-23

Abstract Background Maternal pre-gestational diabetes (PGDM), gestational mellitus (GDM), and overweight/obesity have been associated with increased risks of offspring neurodevelopmental conditions (NDCs) including autism, intellectual disability (ID), attention deficit/hyperactivity disorder (ADHD). Less is known about whether how obstetric neonatal complications (e.g., preterm birth, asphyxia) could mediate these associations. Methods In this Swedish register-based cohort study, we...

10.1186/s12916-023-03116-x article EN cc-by BMC Medicine 2023-11-07

Abstract Background Gestational diabetes mellitus (GDM) is associated with both short- and long-term risks, although it unknown if risks vary by severity, timing, duration of gestational hyperglycemia. We aimed to identify trajectories random capillary glucose (RCG) levels throughout pregnancy assess their associations obstetric/neonatal outcomes children’s risk neurodevelopmental conditions (NDCs) (i.e., autism, intellectual disability, attention-deficit/hyperactivity disorders [ADHD])....

10.1186/s12916-023-02926-3 article EN cc-by BMC Medicine 2023-07-19

Abstract A multipollutant model, the Community Multiscale Air Quality model paired with Model of Aerosol Dynamics, Reaction, Ionization, and Dissolution (CMAQ-MADRID), is extended to include a comprehensive treatment mercury processes applied simulation atmospheric deposition sulfate over United States during 1996. performance evaluated first by comparison annual wet data from National Atmospheric Deposition Program’s Trends Network; coefficient determination r 2 0.77, normalized error bias...

10.1175/jam2536.1 article EN other-oa Journal of Applied Meteorology and Climatology 2007-09-01

Vascular dementia (VD) is a disease characterized by cognitive impairment and memory loss due to brain cell damage caused cerebral vascular ischemia. Danggui-Shaoyao-San (DSS) has been used clinically treat diseases for centuries. The VD model was established bilateral common carotid artery (BCCA) repeated ischemia-reperfusion (I/R) caudal bleeding. Target prediction of DSS miR-124 in PI3K/Akt signaling pathway network pharmacology. effect on dysfunction were evaluated through methods such...

10.1016/j.brainres.2024.149135 article EN cc-by-nc-nd Brain Research 2024-08-22

Viral encephalitis (VE) is one of the common diseases children with intracranial infection, it has come on urgent, progress fast, and clinical features severe cases may even lead to disability, death, other serious adverse prognostic outcomes, so seek in early diagnosis prognosis efficiency relevant indicators stop time take effective means prevent further development great significance. Neopterin (NPT), as a factor that plays an important role process validation development, been relatively...

10.5937/jomb0-43317 article EN cc-by Journal of Medical Biochemistry 2023-06-28

Abstract Background Benign monomelic amyotrophy of lower limb (BMALL) is a neurogenic syndrome representing an unclear field. Further studies might be helpful to elucidate uncertainties regarding causation, outcome, and the risk progression amyotrophic lateral sclerosis (ALS). Methods According inclusion exclusion criteria, 37 patients with BMALL were retrospectively collected in three neuromuscular centers from January 2012 October 2018. The detailed medical data summarized. Multiple...

10.1002/brb3.2073 article EN cc-by Brain and Behavior 2021-03-02

ISEE-0914 Objectives: The objective of this study was to explore the association between traffic-related air pollution exposure and its impacts children’s neurobehavioral functions. Methods: A field conducted in Quanzhou, China where two primary schools were chosen based on traffic density monitoring data ambient pollutants. School located polluted area B clear area. Nitrogen dioxide (NO2) PM10 at campus classroom monitored as indicators for pollution. battery manual computerized testing...

10.1097/01.ede.0000362766.07163.e1 article EN Epidemiology 2009-11-01

Objective To assess the severity distribution proportion and quality of life (QOL) chronic obstructive pulmonary disease(COPD)among population in Southern China.Methods Data were from cross-sectional survey COPD which was conducted an urban a rural Guangdong for residents aged over 40 years old.The recruited populations interviewed with questionnaire tested spirometry.Those less than 70% post-bronchodialator FEV1/FVC identified as COPD.The assessed 12-item Short-Form health (SF-12).Groups...

10.3760/cma.j.issn.1673-436x.2014.13.007 article EN Chinese Journal of Asthma 2014-07-05

Objective To discuss the effect of comfort nursing in treatment acute abdomen laparoscopic operation. Methods A total 86 patients with department general surgery were divided into group and control group. The was treated care, while used traditional care. length hospitalization (days), out-of-bed activities, catheter indwelling time (h), complications, cooperation degree satisfaction level compared between two groups. Results The activities (h) (5.35±1.40) d, (10.44±3.29)h,...

10.3760/cma.j.issn.1674-2907.2015.15.009 article EN Zhonghua xiandai huli zazhi 2015-05-26

Objective: Oral health denotes general well-being, meaning that the person can perform functions such as eating, talking, and keeping smile. Those impact on oral health-related quality of life (OHRQoL) with differences between sexes. In this study, we intended to examine sex behaviors in OHRQoL among institutionalized patients schizophrenia. Methods: We recruited 150 (99 men 51 women) schizophrenia a nursing home. measured 36-item Short-form Health Survey (SF-36) questionnaire, by cleaning...

10.4103/tpsy.tpsy_35_20 article EN cc-by-nc-sa Taiwanese Journal of Psychiatry 2020-01-01
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