Olof Stephansson

ORCID: 0000-0003-1528-4563
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About
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Research Areas
  • Pregnancy and preeclampsia studies
  • Maternal and Perinatal Health Interventions
  • Pregnancy and Medication Impact
  • Gestational Diabetes Research and Management
  • Birth, Development, and Health
  • Maternal and fetal healthcare
  • Neonatal Respiratory Health Research
  • Maternal Mental Health During Pregnancy and Postpartum
  • COVID-19 Impact on Reproduction
  • Assisted Reproductive Technology and Twin Pregnancy
  • Reproductive System and Pregnancy
  • Global Maternal and Child Health
  • Bariatric Surgery and Outcomes
  • Pregnancy-related medical research
  • Cardiovascular Issues in Pregnancy
  • Reproductive Health and Contraception
  • Pelvic floor disorders treatments
  • Cancer Risks and Factors
  • Liver Disease Diagnosis and Treatment
  • Neonatal and fetal brain pathology
  • Eosinophilic Esophagitis
  • Celiac Disease Research and Management
  • Endometriosis Research and Treatment
  • Infant Development and Preterm Care
  • Liver Diseases and Immunity

Karolinska Institutet
2016-2025

Karolinska University Hospital
2016-2025

Uppsala University Hospital
2024

Children's & Women's Health Centre of British Columbia
2023

University of British Columbia
2019-2023

Svenska Örtmedicinska Institute
2023

Faculty of Media
2023

Council of Science Editors
2023

Minneapolis Institute of Arts
2023

Johnson University
2023

Maternal obesity is associated with increased risks of gestational diabetes, large-for-gestational-age infants, preterm birth, congenital malformations, and stillbirth. The these outcomes among women who have undergone bariatric surgery are unclear.We identified 627,693 singleton pregnancies in the Swedish Medical Birth Register from 2006 through 2011, which 670 occurred had previously for whom presurgery weight was documented. For each pregnancy after surgery, up to five control were...

10.1056/nejmoa1405789 article EN New England Journal of Medicine 2015-02-25

To investigate Swedish women's level of antenatal fear childbirth at various gestational ages, and factors associated with intense preference for cesarean section.A cross-sectional study.All clinics in four geographical areas.Thousand six hundred thirty-five pregnant women ages recruited during September-October 2006.A questionnaire completed the clinic. The reported their appraisal approaching delivery according to Wijma Delivery Expectancy/Experience Questionnaire (W-DEQ).The preferred...

10.1080/00016340902998436 article EN Acta Obstetricia Et Gynecologica Scandinavica 2009-06-03

To study the risk of adverse pregnancy outcomes in women with polycystic ovary syndrome, taking into account maternal characteristics and assisted reproductive technology.Population based cohort study.Singleton births registered Swedish medical birth register between 1995 2007.By linkage patient register, 3787 among a diagnosis syndrome 1,191,336 without such diagnosis.Risk (gestational diabetes, pre-eclampsia, preterm birth, stillbirth, neonatal death, low Apgar score (<7 at five minutes),...

10.1136/bmj.d6309 article EN cc-by-nc BMJ 2011-10-13

Objective To determine the risk for adverse pregnancy and fetal outcomes in intrahepatic cholestasis of ( ICP ). Design Population‐based cohort study. Setting S wedish Medical Birth Register MBR ) 1997–2009. Population A total 1 213 668 singleton deliveries. Methods Linkage H ospital D ischarge R egister exposure ; n = 5477) with covariates. Main outcome measures Gestational diabetes, pre‐eclampsia, prematurity, stillbirth. Results Intrahepatic was diagnosed 0.32–0.58% all pregnancies, an...

10.1111/1471-0528.12174 article EN BJOG An International Journal of Obstetrics & Gynaecology 2013-02-19

<b>Objective</b> To assess whether maternal use of selective serotonin reuptake inhibitors (SSRIs) increases the risk persistent pulmonary hypertension in newborn, and such an effect might differ between specific SSRIs. <b>Design</b> Population based cohort study using data from national health registers. <b>Setting</b> Denmark, Finland, Iceland, Norway, Sweden, 1996-2007. <b>Participants</b> More than 1.6 million infants born after gestational week 33. <b>Main outcome measures</b> Risks...

10.1136/bmj.d8012 article EN cc-by-nc BMJ 2011-01-12

<b>Objective</b>&nbsp;To estimate the risks of major congenital malformations in offspring mothers who are underweight (body mass index (BMI) &lt;18.5), overweight (BMI 25 to &lt;30), or obesity classes I 30 &lt;35), II (35 &lt;40), III (≥40) compared with normal weight 18.5 &lt;25) early pregnancy. <b>Design</b>&nbsp;Population based cohort study. <b>Setting</b>&nbsp;Nationwide Swedish registries. <b>Participants</b>&nbsp;1 243 957 liveborn singleton infants from 2001 2014 Sweden. Data on...

10.1136/bmj.j2563 article EN cc-by-nc BMJ 2017-06-14

Importance Since 2004-2007, national guidelines and recommendations have been developed for the management of extremely preterm births in Sweden. If how more uniform has affected infant survival is unknown. Objective To compare infants born during 2004-2007 with 2014-2016. Design, Setting Participants All at 22-26 weeks’ gestational age (n = 2205) between April 1, 2004, March 31, 2007, January 2014, December 2016, Sweden were studied. Prospective data collection was used 2004-2007. Data...

10.1001/jama.2019.2021 article EN JAMA 2019-03-26

Intrahepatic cholestasis of pregnancy (ICP) is the most common liver disease in pregnancy. We aimed to estimate risk developing hepatobiliary women with ICP and odds prevalent disease. analyzed data births between 1973 2009 registered Swedish Medical Birth Register. By linkage Patient Register, we identified 11,388 who were matched 113,893 without this diagnosis. Diagnoses preexisting or later obtained from Main outcome measures hazard ratios (HRs) for (ORs) Risk estimates calculated through...

10.1002/hep.26444 article EN Hepatology 2013-04-08

<h3>Importance</h3> The outcomes of newborn infants women testing positive for SARS-CoV-2 in pregnancy is unclear. <h3>Objective</h3> To evaluate neonatal relation to maternal test positivity pregnancy. <h3>Design, Setting, and Participants</h3> Nationwide, prospective cohort study based on linkage the Swedish Pregnancy Register, Neonatal Quality Register Communicable Diseases. Ninety-two percent all live births Sweden between March 11, 2020, January 31, 2021, were investigated by 8, 2021....

10.1001/jama.2021.5775 article EN JAMA 2021-04-29
Clara Calvert Meredith Brockway Helga Zoëga Jessica E. Miller Jasper V. Been and 95 more A. Kofi Amegah Amy Racine-Poon Solmaz Eradat Oskoui Ishaya I. Abok Nima Aghaeepour Christie Akwaowo Belal Alshaikh Adejumoke Idowu Ayede Fabiana Bacchini Behzad Barekatain Rodrigo Barnes Karolina Bebak Anick Bérard Zulfiqar A Bhutta Jeffrey R. Brook Lenroy Bryan Kim N. Cajachagua‐Torres Marsha Campbell‐Yeo Dinh‐Toi Chu Kristin L. Connor Luc Cornette Sandra Cortés Mandy Daly Christian Debauche Iyabode Olabisi Florence Dedeke Kristjana Einarsdóttir Hilde Engjom Guadalupe Estrada‐Gutiérrez Ilaria Fantasia Nicole Fiorentino Meredith Franklin Abigail Fraser Onesmus Gachuno Linda A. Gallo Mika Gissler Siri E. Håberg Abbas Habibelahi Jonas Häggström Lauren Hookham Lisa Hui Luis Huicho Karen J. Hunter Sayeeda Huq Ashish KC Seilesh Kadambari Roya Kelishadi Narjes Khalili Joanna Kippen Kirsty Le Doaré Javier Llorca Laura A. Magee Maria C. Magnus Kenneth K. C. Man Patrick Mburugu Rishi P. Mediratta Andrew D. Morris Nazeem Muhajarine Rachel Mulholland Livia Nagy Bonnard Victoria Nakibuuka Natasha Nassar Sylvester Dodzi Nyadanu Laura Oakley Adesina Oladokun Oladapo Olayemi Olanike Abosede Olutekunbi Rosena O. Oluwafemi Taofik Oluwaseun Ogunkunle Chris Orton Anne K. Örtqvist Joseph Ouma Oyejoke Oyapero Kirsten R. Palmer Lars Henning Pedersen Gavin Pereira Isabel Pereyra Roy K. Philip Dominik Pruski Marcin Przybylski Hugo G. Quezada‐Pinedo Annette K. Regan Natasha Rhoda Tonia Rihs Taylor Riley Thiago Augusto Hernandes Rocha Daniel L. Rolnik Christoph Saner Francisco J. Schneuer Vivienne Souter Olof Stephansson Shengzhi Sun Emma Swift Miklós Szabó Marleen Temmerman Lloyd Tooke

Abstract Preterm birth (PTB) is the leading cause of infant mortality worldwide. Changes in PTB rates, ranging from −90% to +30%, were reported many countries following early COVID-19 pandemic response measures (‘lockdowns’). It unclear whether this variation reflects real differences lockdown impacts, or perhaps stillbirth rates and/or study designs. Here we present interrupted time series and meta-analyses using harmonized data 52 million births 26 countries, 18 which had representative...

10.1038/s41562-023-01522-y article EN cc-by Nature Human Behaviour 2023-02-27

Abstract Objective To assess long term neurodevelopmental outcomes of children born at different gestational ages, particularly 32-33 weeks (moderately preterm) and 34-36 (late preterm), compared with 39-40 (full term). Design Nationwide cohort study. Setting Sweden. Participants 1 281 690 liveborn singleton without congenital malformations 32 +0 to 41 +6 between 1998 2012. Main outcome measures The primary interest were motor, cognitive, epileptic, hearing, visual impairments a composite...

10.1136/bmj-2023-075630 article EN cc-by BMJ 2024-01-24

Importance Several studies suggest that acetaminophen (paracetamol) use during pregnancy may increase risk of neurodevelopmental disorders in children. If true, this would have substantial implications for management pain and fever pregnancy. Objective To examine the associations with children’s autism, attention-deficit/hyperactivity disorder (ADHD), intellectual disability. Design, Setting, Participants This nationwide cohort study sibling control analysis included a population-based...

10.1001/jama.2024.3172 article EN JAMA 2024-04-09

Importance Better knowledge about neonatal adverse events after COVID-19 vaccination during pregnancy could help address concerns vaccine safety. Objective To evaluate the risks of exposure to pregnancy. Design, Setting, and Participants Population-based cohort study including all infants in Sweden Norway born from June 2021 January 2023. Unique personal identity numbers were used link individual information different national registers. Exposure Administration any mRNA against pregnancy,...

10.1001/jama.2023.26945 article EN JAMA 2024-02-06

BACKGROUNDEndometriosis, a common gynaecological disease, is characterized by local and systemic inflammation, which may cause infertility consequently, increased utilization of assisted reproduction technology (ART). We aimed to estimate the risk for preterm birth, small-for-gestational-age (SGA) stillbirth, Caesarean section, pre-eclampsia antepartal haemorrhage among women with previous diagnosis endometriosis compared no endometriosis.

10.1093/humrep/dep186 article EN Human Reproduction 2009-05-12

Some causes of stillbirth may also lead to fetuses that are small for gestational age (have a low birth weight with respect their age) or delivered preterm (before 37 weeks gestation). It is not known whether the previous small-for-gestational-age infant increases subsequent risk stillbirth.

10.1056/nejmoa031587 article EN New England Journal of Medicine 2004-02-18

Preeclampsia is a leading cause of maternal and infant mortality morbidity worldwide. Both Swedish snuff cigarette smoke include nicotine, but combustion products accompany only smoking. The aims this study were to compare the effects smoking on preeclampsia risk estimate whether changes in tobacco habits during pregnancy affect developing term preeclampsia. We used information from Birth Register all singleton births Sweden years 1999–2006 (n=612 712). Compared with nontobacco users, women...

10.1161/hypertensionaha.109.147082 article EN Hypertension 2010-03-16
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