A5084447497- Health, Environment, Cognitive Aging
- Geology and Paleoclimatology Research
- Cryospheric studies and observations
- Dementia and Cognitive Impairment Research
- Health disparities and outcomes
- Geological formations and processes
- Ethics in Clinical Research
- Chronic Disease Management Strategies
- Privacy-Preserving Technologies in Data
- Climate change and permafrost
- Data-Driven Disease Surveillance
- Data Quality and Management
- COVID-19 Clinical Research Studies
- Cardiovascular Conditions and Treatments
- Landslides and related hazards
- COVID-19 epidemiological studies
- COVID-19 and healthcare impacts
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Mobile Health and mHealth Applications
- Artificial Intelligence in Healthcare and Education
- Methane Hydrates and Related Phenomena
- Effects of Radiation Exposure
- COVID-19 and Mental Health
- Research Data Management Practices
Durham University
2009-2025
Swansea University
2018-2024
Health Data Research UK
2020-2023
Sail To Prevail
2022
Databank (Italy)
2022
Catalyst Health Economics Consultants Ltd
2019
Royal Brompton & Harefield NHS Foundation Trust
2019
Colorado State University
2009-2016
Pacific Northwest National Laboratory
2011
The Christie NHS Foundation Trust
1998-1999
To determine the effect of population level implementation a test-and-treat approach to correction suboptimal vitamin D status (25-hydroxyvitamin (25(OH)D) <75 nmol/L) on risk all cause acute respiratory tract infection and covid 19.Phase 3 open label randomised controlled trial.United Kingdom.6200 people aged ≥16 years who were not taking supplements at baseline.Offer postal finger prick test blood 25(OH)D concentration with provision six month supply lower dose (800 IU/day, n=1550) or...
Abstract Preterm birth (PTB) is the leading cause of infant mortality worldwide. Changes in PTB rates, ranging from −90% to +30%, were reported many countries following early COVID-19 pandemic response measures (‘lockdowns’). It unclear whether this variation reflects real differences lockdown impacts, or perhaps stillbirth rates and/or study designs. Here we present interrupted time series and meta-analyses using harmonized data 52 million births 26 countries, 18 which had representative...
A 1:6250 map of the foreland Fláajökull's north lobe as it appeared in 1989, together with a 1:350 scale sample area recently exposed glacial landforms from 2014, enables an assessment spatial and temporal evolution landform assemblages at margin active temperate piedmont terminating ice-marginal thickening till wedges. The pattern development captured these maps indicates that glacier developed strong longitudinal crevassing well-developed pecten (three-dimensional crenulations) during its...
Abstract The Dementias Platform UK Data Portal is a data repository facilitating access to for 3 370 929 individuals in 42 cohorts. an end-to-end management solution providing secure, fully auditable, remote environment the analysis of cohort data. All projects utilising are by default collaborations with research teams generating uses Secure eResearch infrastructure provide three core utilities: discovery, access, and analysis. These delivered using 7 layered architecture comprising:...
Introduction The emergence of the novel respiratory SARS-CoV-2 and subsequent COVID-19 pandemic have required rapid assimilation population-level data to understand control spread infection in general vulnerable populations. Rapid analyses are needed inform policy development target interventions at-risk groups prevent serious health outcomes. We aim provide an accessible research platform determine demographic, socioeconomic clinical risk factors for infection, morbidity mortality COVID-19,...
In the North Atlantic region, transition from very cold Lateglacial Stadial (GS-1) to temperate Holocene was abrupt, with a rapid increase in temperature of several degrees, after which low-stature, cold-tolerant vegetation replaced through immigration and succession tall herb, heath, shrub communities towards Betula woodland varying density. northeast England, pollen diagrams on south north transect between mid-Yorkshire Scottish border show that there considerable variation rate at...
IntroductionThe UK Longitudinal Linkage Collaboration (UK LLC) is the national Trusted Research Environment (TRE) for UK's longitudinal research community, supporting unparalleled collection of Population Studies (LPS). Initially set up as a COVID-19 resource, LLC now generic database any public good. ObjectivesUK supports by providing record linkage and TRE services. MethodsThe partnership provides secure analytics environment, trusted third-party processor comprehensive governance...
A 1:15,000 scale map of the glacial geomorphology and surficial geology Heinabergsjökull Skalafellsjökull glacier forelands in southeast Iceland depicts a landsystem imprint actively receding temperate glaciers mountain terrain with high glacifluvial sediment yield. The is characterised by three diagnostic depositional domains for active systems (marginal morainic; subglacial; glacifluvial/glacilacustrine) together site-specific landform-sediment assemblages indicative jökulhlaup drainage...
A contoured surficial geology and geomorphology map of the forelands Hørbyebreen, Svenbreen Ferdinandbreen valley glaciers in Petuniabukta, Svalbard was compiled from an orthophotograph based upon aerial photographs taken 2009. The reveals typical polythermal glacial landsystems, comprising ice-cored latero-frontal moraine arcs grading up into fluted till surfaces draped by supraglacially-derived longitudinal debris stripes. additional occurrence on Hørbyebreen foreland linear esker ridges...
A 1:5700 scale map of the recently deglaciated foreland Skaftafellsjökull, Iceland as it appeared in 2007, depicts a typical active temperate glacial landsystem with clear pattern sequentially changing push moraine morphologies, including remarkable hairpin-shaped moraines, indicative spatial and temporal variability process-form regimes glacier sub-marginal settings. Similar to other Icelandic forelands, this demonstrates that piedmont lobes region have developed strong longitudinal...
Research-ready data (data curated to a defined standard) increase scientific opportunity and rigour by integrating the environment. The development of research platforms has highlighted value research-ready data, particularly for multi-cohort analyses. Following stakeholder consultation, standard model (C-Surv) optimised discovery, was developed using from 5 population clinical cohort studies. uses four-tier nested structure based on 18 themes selected according user behaviour or technology....
Abstract Please click here to download the map associated with this article. A1:30,000 scale of snout and proglacial landscape surging Icelandic glacier Tungnaárjökull, based upon aerial photography from 1995, immediately after a surge, allows an assessment spatial variability in landform-sediment imprints catastrophic advance across upland bedrock ridges. The ice-margin parallel alignment ridges locally strongly directs meltwater drainage initiates strong compression ice during surging,...
Electronic healthcare records (EHRs) are an important resource for health research that can be used to improve patient outcomes in chronic respiratory diseases. However, consistent approaches the analysis of these datasets needed coherent messaging, and when undertaking comparative studies across different populations.
The rising burden of dementia is a global concern, and there need to study its causes, natural history outcomes. Secure Anonymised Information Linkage (SAIL) Databank contains anonymised, routinely-collected healthcare data for the population Wales, UK. It has potential be valuable resource research owing size, long follow-up time prospective collection during clinical care.We aimed apply reproducible methods create SAIL e-cohort (SAIL-DeC). We created SAIL-DeC with view maximising utility...
The novel coronavirus SARS-CoV-2, which emerged in December 2019, has caused millions of deaths and severe illness worldwide. Numerous vaccines are currently under development a few have now been authorised for population-level administration by several countries. As 20 September 2021, over 48 million people received their first vaccine dose 44 second across the UK. We aim to assess uptake rates, effectiveness, safety all approved COVID-19 UK.We will use prospective cohort study designs...
A 1:4470 map of the Morsárjökull foreland, southern Iceland shows spatial distribution post Little Ice Age glacial sediment–landform associations pertaining to operation a typical active temperate outlet glacier south Vatnajökull ice cap. The depicts an exemplar for debris-charged glaciated valley landsystem, with characteristics further indicative 'uncovered alpine glaciers', such as uneven moraine volume, localized appearance fluted subglacial bed and within-valley lateral asymmetry. Such...
A surficial geology and geomorphology map of the forelands Sandfellsjökull Oldufellsjökull piedmont lobes east Mýrdalsjökull ice cap is used to characterise historical modern landscape imprint in a glacial landsystems context. This serves as analogue for palaeoglaciological reconstructions systems that operated outlet contrasting dynamics, but subtle variability process-form regimes encoded geomorphology. The two reflect significantly different regimes, hence glacier despite fact they are...
A 1:14 500 scale glacial geomorphology and surficial geology map of the foreland Hoffellsjökull, southeast Iceland is used to assess landsystem signature contrasting glacier-climate interactions two separate flow lobes within one outlet glacier. This constitutes a valuable modern analogue for employing geomorphological signatures as palaeoclimate indicators in ancient deglaciated terrains. The glacier's lobes, Svínafellsjökull are distinctly different. displays inset seasonally...
ABSTRACT Background Coronavirus disease 2019 (COVID-19), caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is estimated to have more than 18 million deaths worldwide as of end-May 2022. Methods COVIDENCE UK a longitudinal population-based study that investigates risk factors for, and impacts of, COVID-19 in residents aged ≥16 years. A unique feature capacity support trial-within-cohort studies evaluate interventions for prevention other illnesses. Participants...
Abstract Please click here to download the map associated with this article. A surficial geology and geomorphology of Satujökull foreland northern Hofsjökull ice cap in central Iceland provides a clear signature spatial temporal change glacial landsystem signatures as result complex glacier behaviour historical period. Landsystem 1, indicative polythermal conditions, comprises wide arc ice-cored moraine controlled ridges lying outside fluted drumlinized terrain demarcates Little Ice Age...
Three maps are presented that portray the periglacial geomorphology of three summit areas Bodmin Moor, Cornwall, SW England, including Brown Willy (scale 1:2630), Kilmar/Bearah/Sharp tors 1:3335) and Rough/Little Rough/Showery 1:2175). Landform elements include castellated with well-developed cantilevered or precariously balanced corestones, blockfields, rock-fronted lobes thought to record former permafrost creep, patterned ground (stripes) lower slope accumulations crudely stratified...