A5071828669- Child Abuse and Trauma
- Migration, Health and Trauma
- HIV/AIDS Research and Interventions
- Posttraumatic Stress Disorder Research
- Child and Adolescent Psychosocial and Emotional Development
- Homelessness and Social Issues
- Intimate Partner and Family Violence
- Psychotherapy Techniques and Applications
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Suicide and Self-Harm Studies
- Attention Deficit Hyperactivity Disorder
- Sex work and related issues
- Sleep and related disorders
- Treatment of Major Depression
- Syphilis Diagnosis and Treatment
- Mobile Health and mHealth Applications
- Homicide, Infanticide, and Child Abuse
- Health disparities and outcomes
- Influenza Virus Research Studies
- Schizophrenia research and treatment
- Personality Disorders and Psychopathology
- Adolescent Sexual and Reproductive Health
- Psychosomatic Disorders and Their Treatments
Public Health Agency
2025
University of Ulster
2012-2024
Irish Hospice Foundation
2024
London North West Healthcare NHS Trust
2004-2024
Queen's University Belfast
2021-2024
Royal Victoria Hospital
2023-2024
Royal College of Surgeons in Ireland
2023
University of Southern Denmark
2014-2021
University of Otago
2021
Universiti Malaysia Sarawak
2018
BackgroundCurrent UK vaccination policy is to offer future COVID-19 booster doses individuals at high risk of serious illness from COVID-19, but it still uncertain which groups the population could benefit most. In response an urgent request Joint Committee on Vaccination and Immunisation, we aimed identify factors for severe outcomes (ie, COVID-19-related hospitalisation or death) in who had completed their primary schedule received first vaccine.MethodsWe constructed prospective cohorts...
The 2024/25 influenza season in Europe is currently characterised by co-circulation of A(H1N1)pdm09, A(H3N2) and B/Victoria viruses, with A(H1N1)pdm09 predominating. Interim vaccine effectiveness (VE) estimates from eight European studies (17 countries) indicate an all-age A VE 32–53% primary care 33–56% hospital settings, some signals lower subtype higher against B (≥ 58% across settings). Where feasible, vaccination should be encouraged other prevention measures strengthened.
Objective To determine the safety and efficacy of liposomal amphotericin B (AmBisome) in primary treatment AIDS-associated cryptococcosis. Design A Phase II, multicentre, European, non-comparative, open study to assess use AmBisome 23 patients (26 enrolments) with Dose requirements, mycological response toxicity were documented. Setting Hospital-based HIV units. Patients Twenty-three HIV-t-seropositive patients. Results Drug toxicity, assessed 25 enrolments, was well-tolerated little renal,...
This study assessed the dimensional structure of UCLA Loneliness Scale ([UCLA-LS], UCLA-3). Data from Northern Ireland Young Life and Times Survey (2011), a survey 1,434 16-year-olds, was used to examine underlying factor scale. Confirmatory analysis employed compare alternative analytical models that can inform scoring measure determine degree which different factors provided unique predictive utility. Fit statistics indicated best fitting model comprised three correlated factors:...
The International Classification of Diseases (ICD-11) is currently under development with proposed changes recommended for the posttraumatic stress disorder (PTSD) diagnosis and inclusion a separate complex PTSD (CPTSD) disorder. Empirical studies support distinction between CPTSD; however, less research has focused on non-western populations.The aim this study was to investigate whether distinct CPTSD symptom classes emerged identify potential risk factors severity impairment associated...
While population estimates suggest high vaccine effectiveness against SARS-CoV-2 infection, the protection for health care workers, who are at higher risk of exposure, is less understood.
Snake-bite mortality among a rural population in Kenya was estimated to be 6.7/100,000 people each year, representing 0.7% of all deaths. A community-based retrospective survey 4712 households provided estimates the incidence snake bite this population. Although 151/100,000 are bitten only 19% these by potentially venomous snakes. When those who had been were shown photographs range locally prevalent snakes, most indicated that both and non-venomous snakes capable causing death. Most (68%)...
Repeated assessments of psychopathology, together with personality status, were made over two years on 181 psychiatric out-patients generalised anxiety disorder (59), panic (66), or dysthymic (56) diagnosed using an interview schedule for DSM–III. Patients randomly allocated to drug treatment, cognitive and behaviour therapy, a self-help treatment programme. Although there no overall differences in compliance rate efficacy between the three modes psychological methods, particularly...
Using a double-blind procedure, 68 patients with putative benzodiazepine dependence were randomly allocated to one of three groups given lorazepam ( n = 22), diazepam 23) or bromazepam in doses equivalent those the patients' original benzodiazepine. After four weeks dosage was reduced 25% quantities until no further benzodiazepines taken. A total 23 dropped out during study, ten on (one whom committed suicide), seven and six bromazepam. There few differences withdrawal symptoms between but,...
Fifty-one outpatients presenting with generalised anxiety disorder were included in a double-blind trial, and treated either buspirone (a new non-benzodiazepine antianxiety drug) or diazepam over 6 12 weeks, after which they abruptly withdrawn continued on placebo to 14 weeks. Ratings of other symptoms administered fortnightly additional withdrawal noted. Forty patients completed the study; 8 11 drop-outs taking buspirone. Both drugs reduced anxiety, more rapidly, but greater symptoms,...
This study aimed to explore a broad range of psychological reactions trauma in sample bereaved parents order assess whether the traumatic framework is adequate for describing entire emotional infant death. A (N = 455) who lost their child through perinatal or postnatal loss were compared control group 110) gave birth healthy child. Multivariate regression analysis clearly demonstrated that scored significantly higher on Depression, Anxiety, Dissociation, Sleep Disturbances, Somatization,...
Background: Psychological trauma has only recently been considered a traumatic event. Therefore, research on Posttraumatic Stress Disorder (PTSD) and Complex-PTSD following exposure to psychological violence, is less studied compared with physical sexual violence. Objectives: This study aimed establish the prevalence of PTSD C-PTSD among female victims partner violence (IPV) examine unique association between different subtypes IPV (i.e. physical, IPV) response. Methods: The includes...
Background Post-authorisation vaccine safety surveillance is well established for reporting common adverse events of interest (AEIs) following influenza vaccines, but not COVID-19 vaccines. Aim To estimate the incidence AEIs presenting to primary care vaccination in England, and report profile differences between brands. Methods We used a self-controlled case series design relative (RI) reported national sentinel network, Oxford-Royal College General Practitioners Clinical Informatics...
Synopsis Two hundred and ten psychiatric patients with one of three DSM-III diagnoses, generalized anxiety disorder ( N = 71), panic 74) or dysthymic 65), were included in a clinical trial which diazepam, dothiepin placebo tablets, cognitive behaviour therapy, self-help package given over weeks. Personality status was assessed independently using structured interview, the Assessment Schedule. One ninety-eight had personality assessments, 89% close informant. Thirty-six per cent these more...
Objective Previous research has identified an association between loneliness and psychiatric morbidity, but many of the studies have been based on small convenience samples not always used standardized measures. Aims Methods This study aimed to assess measures morbidity using data from a large sample adolescents Northern Ireland (Young Life Times Survey, 2011). A total 1,434 participants completed survey. Results The prevalence was 15.6% 28.4% respectively. multivariate binary logistic...
ObjectiveThe present study investigated the relationship between different types of childhood maltreatment (emotional, sexual, overall abuse, and no abuse) symptoms attention deficit hyperactivity disorder (ADHD) in young adulthood.MethodData were collected from a Danish national conducted by The National Centre for Social Research 2008 2009. A sample 4,718 adults (24 years age) randomly selected using total birth cohort children born 1984. Structured interviews with response rate 63%,...
Objective Previous research has identified an association between traumatic experiences and psychotic symptoms. Few studies, however, have explored the underlying mechanisms contingent nature of these associations in integrated model. This study aimed to test a moderated mediation model negative childhood experiences, associated cognitive processes, within context adolescent loneliness. Design Cross‐sectional survey. Methods A total 785 N orthern I rish secondary school adolescents completed...