A5000608791- Respiratory viral infections research
- Influenza Virus Research Studies
- Gut microbiota and health
- Human-Animal Interaction Studies
- SARS-CoV-2 detection and testing
- Microbial Community Ecology and Physiology
- SARS-CoV-2 and COVID-19 Research
- Metabolomics and Mass Spectrometry Studies
- Viral gastroenteritis research and epidemiology
- Bacterial Infections and Vaccines
- Nutrition, Genetics, and Disease
- Clostridium difficile and Clostridium perfringens research
- Reproductive tract infections research
- Marine animal studies overview
- Viral Infections and Outbreaks Research
- Bioinformatics and Genomic Networks
- Pneumonia and Respiratory Infections
- Marine and fisheries research
- RNA and protein synthesis mechanisms
- Coral and Marine Ecosystems Studies
- COVID-19 epidemiological studies
- Molecular Biology Techniques and Applications
University of Copenhagen
2018-2025
Statens Serum Institut
2022-2025
Natural History Museum Aarhus
2018
Background Between October 2022 and January 2023, influenza A(H1N1)pdm09, A(H3N2) B/Victoria viruses circulated in Europe with different (sub)types dominating areas. Aim To provide interim 2022/23 vaccine effectiveness (VE) estimates from six European studies, covering 16 countries primary care, emergency care hospital inpatient settings. Methods All studies used the test-negative design, but differences other study characteristics, such as data sources, patient selection, case definitions...
The 2024/25 influenza season in Europe is currently characterised by co-circulation of A(H1N1)pdm09, A(H3N2) and B/Victoria viruses, with A(H1N1)pdm09 predominating. Interim vaccine effectiveness (VE) estimates from eight European studies (17 countries) indicate an all-age A VE 32–53% primary care 33–56% hospital settings, some signals lower subtype higher against B (≥ 58% across settings). Where feasible, vaccination should be encouraged other prevention measures strengthened.
We estimated interim influenza A vaccine effectiveness (VE) following a late sharp rise in cases during an A(H3N2)-dominated 2021/22 season, after lifting COVID-19 restrictions. In children aged 2-6 years offered live attenuated vaccine, adjusted VE was 62.7% (95% CI: 10.9-84.4) hospitalised and 64.2% 50.5-74.1) non-hospitalised children. patients 7-44 years, 24.8% 12.8-35.2); non-significant remaining age groups hospital/non-hospital settings.
Rapid and accurate detection of viral respiratory infections is important for infection control measures. This study compares the analytical clinical performance Xpert® Xpress CoV-2/Flu/RSV plus test ("Xpert", Cepheid) STANDARD™ M10 Flu/RSV/SARS-CoV-2 ("M10", SD Biosensor). Both tests are quadruplex RT-PCR assays rapid diagnosis SARS-CoV-2, influenza A/B RSV.
ABSTRACT Successfully adapting to a feral lifestyle with different access food, shelter and other resources requires rapid physiological behavioural changes, which could potentially be facilitated by gut microbiota plasticity. To investigate whether alterations in support this transition lifestyle, we analysed the microbiomes of domestic cats from six geographically diverse locations using genome‐resolved metagenomics. By reconstructing 229 non‐redundant metagenome‐assembled genomes 92 cats,...
This study presents findings captured in the first 1.5 years of Virus Monitoring Denmark (VMD) surveillance system. It describes trends respiratory viruses, related symptoms, and participant demographics behaviors. VMD used self-swabbing self-reported symptoms to monitor viruses general population. Participants were recruited via digital invitations a representative sample population or through workplaces. Symptomatic participants could self-swab register their samples report dedicated...
During the 2024/25 influenza season, enhanced and standard-dose vaccines were available for individuals aged 65 older. Compared with quadrivalent vaccine (QIV), adjuvanted QIV was significantly more effective, an overall effectiveness (VE) of 48% (95% CI: 42-52) vs 33% 24-41) when considering both non-hospitalised hospitalised patients. The high-dose demonstrated similar to QIV. These findings support inclusion in future vaccination programmes.
Abstract A crucial first step in assessing and managing the role impacts of predators on their environment is knowledge foraging behaviour diet. Here, we synthesize previously published newly generated data diet harbour seals, grey ringed seals Baltic Sea region. More than 45 000 otoliths recovered from 3147 samples scats digestive tracts were collected throughout all seasons most sub-basins 1968 to 2013. The revealed a large extent interspecific, spatial, seasonal variation seal diet,...
As metagenomic studies continue to increase in size and complexity, they are often required incorporate data from geographically isolated locations or longitudinal time samples. This represents a technical challenge, given that many of the commonly used methods for sample collection, storage, DNA extraction sensitive differences related time, storage chemistry involved. FTA cards have been previously proposed as simple, reliable cost-efficient method preservation animal faecal microbiomes....
Background Influenza was almost absent for 2 years following the implementation of strict public health measures to prevent spread SARS-CoV-2. The consequence this on infections in different age groups is not yet known. Aim To describe infected with influenza virus 2021/22, first post-pandemic season Denmark, compared previous six seasons, and subtypes circulating therein. Methods Infection hospitalisation incidences per group were estimated from data Danish registries. lineages available...
In March 2022, we observed samples with a negative fluorescent signal (60.5%, n = 43) for the influenza A matrix gene and stronger positive subtype A(H3N2). Forty-three were in InfA (H3N2) (mean Cq 30.9, range 23.9-35.1), 26 of 43 28.0, 23.2-30.6). Our multiplex test is laboratory-developed four-target, four-color reverse-transcription PCR assay targeting gene, subtypes A(H3N2) A(H1N1)pdm09. Several when retested on commercial Point-of-Care assays. As stand-alone target most diagnostic...
Background: Rapid and accurate detection of viral respiratory infections is important for infection control measures. This study compares the analytical clinical performance Xpert® Xpress CoV-2/Flu/RSV plus test (“Xpert”, Cepheid) STANDARD™ M10 Flu/RSV/SARS-CoV-2 (“M10”, SD Biosensor). Both tests are quadruplex RT-PCR assays rapid diagnosis SARS-CoV-2, influenza A/B RSV. Study designAnalytical sensitivities were determined by limit A, B RSV, respectively. Additionally, Xpert was evaluated...
Abstract Feralisation, the process by which domesticated organisms revert to a wild state, is widespread phenomenon across various species. Successfully adapting new environment with different access food, shelter, and other resources requires rapid physiological behavioural changes, could potentially be facilitated gut microbiota plasticity. To investigate whether alterations in support this transition feral lifestyle, we analysed microbiomes of domestic cats from six geographically diverse...
Background: Between October 2022 and January 2023, there has been diverse circulation of influenza A(H1N1)pdm09, A(H3N2) B/Victoria viruses in Europe. Aim: To provide interim 2022/23 vaccine effectiveness (VE) estimates from six European studies, covering 16 countries primary care, emergency care hospital inpatient settings.Methods: All studies used the test-negative design, although differences other study characteristics existed, e.g. data sources, patient selection, case definitions...
As metagenomic studies continue to increase in size and complexity, they are often required incorporate data from geographically isolated locations or longitudinal time samples. This represents a technical challenge, given that many of the commonly used methods for sample collection, storage, DNA extraction sensitive differences related time, storage chemistry involved. FTA cards have been previously proposed as simple, reliable cost-efficient method preservation animal faecal microbiomes....