Ingmar Näslund

ORCID: 0000-0002-3644-3319
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About
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Research Areas
  • Bariatric Surgery and Outcomes
  • Obesity and Health Practices
  • Body Contouring and Surgery
  • Diet and metabolism studies
  • Diabetes Treatment and Management
  • Cardiovascular Disease and Adiposity
  • Esophageal and GI Pathology
  • Cardiovascular Function and Risk Factors
  • Gastric Cancer Management and Outcomes
  • Pharmacology and Obesity Treatment
  • Cardiac, Anesthesia and Surgical Outcomes
  • Nutrition and Health in Aging
  • Hernia repair and management
  • Gestational Diabetes Research and Management
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cardiovascular Issues in Pregnancy
  • Obesity, Physical Activity, Diet
  • Metabolism, Diabetes, and Cancer
  • Enhanced Recovery After Surgery
  • Gastroesophageal reflux and treatments
  • Colorectal Cancer Screening and Detection
  • Cancer Risks and Factors
  • Liver Disease Diagnosis and Treatment
  • Health Systems, Economic Evaluations, Quality of Life
  • Nausea and vomiting management

Örebro University
2015-2024

Örebro University Hospital
2008-2020

Karolinska Institutet
2007-2017

Uppsala University
2017

Obihiro University of Agriculture and Veterinary Medicine
2016

Lindesbergs lasarett
2016

University of Gothenburg
2005-2013

Umeå University
2010

Sahlgrenska University Hospital
1998

Örebro County Council
1991

Obesity is associated with increased mortality. Weight loss improves cardiovascular risk factors, but no prospective interventional studies have reported whether weight decreases overall In fact, many observational suggest that reduction mortality.The prospective, controlled Swedish Obese Subjects study involved 4047 obese subjects. Of these subjects, 2010 underwent bariatric surgery (surgery group) and 2037 received conventional treatment (matched control group). We report on mortality...

10.1056/nejmoa066254 article EN New England Journal of Medicine 2007-08-22

Obesity is a risk factor for cardiovascular events. Weight loss might protect against events, but solid evidence lacking.To study the association between bariatric surgery, weight loss, and events.The Swedish Obese Subjects (SOS) an ongoing, nonrandomized, prospective, controlled conducted at 25 public surgical departments 480 primary health care centers in Sweden of 2010 obese participants who underwent surgery 2037 contemporaneously matched controls received usual care. Patients were...

10.1001/jama.2011.1914 article EN JAMA 2012-01-03

Short-term studies show that bariatric surgery causes remission of diabetes. The long-term outcomes for and diabetes-related complications are not known.To determine the diabetes rates cumulative incidence microvascular macrovascular after surgery.The Swedish Obese Subjects (SOS) is a prospective matched cohort study conducted at 25 surgical departments 480 primary health care centers in Sweden. Of patients recruited between September 1, 1987, January 31, 2001, 260 2037 control 343 2010 had...

10.1001/jama.2014.5988 article EN JAMA 2014-06-10

Weight loss protects against type 2 diabetes but is hard to maintain with behavioral modification alone. In an analysis of data from a nonrandomized, prospective, controlled study, we examined the effects bariatric surgery on prevention diabetes.In this analysis, included 1658 patients who underwent and 1771 obese matched controls (with matching performed group, rather than individual, level). None participants had at baseline. Patients in bariatric-surgery cohort banding (19%), vertical...

10.1056/nejmoa1112082 article EN New England Journal of Medicine 2012-08-22

Maternal obesity is associated with increased risks of gestational diabetes, large-for-gestational-age infants, preterm birth, congenital malformations, and stillbirth. The these outcomes among women who have undergone bariatric surgery are unclear.We identified 627,693 singleton pregnancies in the Swedish Medical Birth Register from 2006 through 2011, which 670 occurred had previously for whom presurgery weight was documented. For each pregnancy after surgery, up to five control were...

10.1056/nejmoa1405789 article EN New England Journal of Medicine 2015-02-25

Associations of obesity with incidence heart failure have been observed, but the causality is uncertain. We hypothesized that gastric bypass surgery leads to a lower compared intensive lifestyle modification in obese people.We included people without previous from Swedish nationwide registry treated structured program and Scandinavian Obesity Surgery Registry. All analyses used inverse probability weights based on baseline body mass index propensity score estimated variables. Treatment...

10.1161/circulationaha.116.025629 article EN cc-by-nc-nd Circulation 2017-03-04

Laparoscopic sleeve gastrectomy (SG) and laparoscopic Roux-en-Y gastric bypass (RYGB) are widely used bariatric procedures for which comparative efficacy safety remain unclear.

10.1001/jamanetworkopen.2023.53141 article EN cc-by-nc-nd JAMA Network Open 2024-01-30

We examined the associations of body mass index (BMI), waist circumference, a history diabetes, and cigarette smoking with risk pancreatic cancer among 37 147 women 45 906 men followed up during 560 666 person-years in Swedish Mammography Cohort Men; 136 incident cases were diagnosed. The multivariate rate ratio (RR) for obese (BMI ⩾30 kg/m2) was 1.81 (95% CI: 1.04–3.15) compared to those BMI 20–25 kg/m2. For difference 20 cm (about two standard deviations) RRs 1.32 0.73–2.37) 1.74...

10.1038/sj.bjc.6602868 article EN cc-by-nc-sa British Journal of Cancer 2005-11-01

To identify risk factors for serious and specific early complications of laparoscopic gastric bypass surgery using a large national cohort patients.Bariatric procedures are among the most common surgical today. There is, however, still need to preoperative intraoperative complications.From Scandinavian Obesity Surgery Registry database, we identified 26,173 patients undergoing primary operation morbid obesity between May 1, 2007, September 30, 2012. Follow-up on day 30 was 95.7%....

10.1097/sla.0000000000000431 article EN Annals of Surgery 2013-12-27

Objective Increased sensitivity to alcohol after gastric bypass has been described. The aim of this study was investigate whether bariatric surgery is associated with problems. Design and Methods prospective, controlled Swedish Obese Subjects (SOS) enrolled 2,010 obese patients who underwent (68% vertical banded gastroplasty (VBG), 19% banding, 13% bypass) 2,037 matched controls. Patients were recruited between 1987 2001. Data on abuse diagnoses, self‐reported consumption, problems obtained...

10.1002/oby.20397 article EN Obesity 2013-03-21

ABSTRACT Gastric bypass surgery constitutes the most common and effective bariatric to treat obesity. leads bone loss, but fracture risk following has been insufficiently studied. Furthermore, association between gastric not studied in patients with diabetes, which is a factor for affected by surgery. In this retrospective cohort study using Swedish national databases, 38,971 obese undergoing were identified, 7758 diabetes 31,213 without. An equal amount of well-balanced controls identified...

10.1002/jbmr.3553 article EN Journal of Bone and Mineral Research 2018-07-16

Objective: To evaluate effect on comorbid disease and weight loss 5 years after Roux-en-Y gastric bypass (RYGB) surgery for morbid obesity in a large nationwide cohort. Background: The number patients having surgical procedures to treat obesity-related are increasing. Yet, population-based, long-term outcome studies few. Methods: Data 26,119 individuals [75.8% women, 41.0 years, body mass index (BMI) 42.8 kg/m2] undergoing primary RYGB between May 1, 2007 June 30, 2012, were collected from 2...

10.1097/sla.0000000000001920 article EN Annals of Surgery 2016-07-16

Background Although bariatric surgery is an effective treatment for type 2 diabetes (T2D) in patients with morbid obesity, further studies are needed to evaluate factors influencing the chance of achieving remission. The objective present study was investigate association between T2D duration and remission after surgery. Methods findings We conducted a nationwide register-based cohort including all adult BMI ≥ 35 kg/m2 who received primary Sweden 2007 2015 identified through Scandinavian...

10.1371/journal.pmed.1002985 article EN cc-by PLoS Medicine 2019-11-20

Aims To investigate the absorption, distribution and elimination of ethanol in women with abnormal gut as a result gastric bypass surgery. Patients who undergo for morbid obesity complain increased sensitivity to effects alcohol after operation. Methods Twelve healthy operated at least 3 years earlier were recruited. other closely matched terms age body mass index (BMI) served control group. After an overnight fast each subject drank 95% v/v (0.30 g kg −1 weight) bolus dose. The was diluted...

10.1046/j.1365-2125.2002.01698.x article EN British Journal of Clinical Pharmacology 2002-12-01

Obesity is associated with increased morbidity rates and pharmaceutical costs. To what extent various medication costs are affected by intentional weight loss unknown.A cross-sectional comparison of the use prescribed pharmaceuticals was conducted in 1286 obese individuals Swedish Obese Subjects (SOS) intervention study 958 randomly selected reference individuals. Medication changes for 6 years after bariatric surgery were evaluated 510 surgically 455 conventionally treated SOS...

10.1001/archinte.162.18.2061 article EN Archives of Internal Medicine 2002-10-14

Objective To compare two bariatric surgical principles with regard to effects on blood pressure and salt intake. Background In most patients surgery induces a sustained weight loss reduced cardiovascular risk profile but the long-term effect is uncertain. Methods Cohort study data from prospective, controlled Swedish Obese Subjects (SOS) involving 480 primary health care centres 25 departments in Sweden. treated non-surgical methods (Controls, n = 1636 1132 at 2 y 10 follow up, respectively)...

10.1371/journal.pone.0049696 article EN cc-by PLoS ONE 2012-11-29

Bariatric surgery is an established treatment for obesity, but knowledge on the long-term incidence of revisional scarce.To determine and type after bariatric in 26 years follow-up participants Swedish Obese Subjects (SOS) study.The SOS study a prospective nonrandomized controlled comparing (banding, vertical banded gastroplasty [VBG], gastric bypass [GBP]) with usual care. The surgeries were conducted at 25 public surgical departments Sweden. Men body mass index values 34 or higher women...

10.1001/jamasurg.2018.5084 article EN JAMA Surgery 2019-01-02
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