A5077353117- Bariatric Surgery and Outcomes
- Diet and metabolism studies
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Obesity and Health Practices
- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- American Constitutional Law and Politics
- Dementia and Cognitive Impairment Research
- Diabetes Management and Education
- Health Promotion and Cardiovascular Prevention
- Liver Disease Diagnosis and Treatment
- Sleep and related disorders
- Body Contouring and Surgery
- Cardiovascular Disease and Adiposity
- Blood Pressure and Hypertension Studies
- Metabolism, Diabetes, and Cancer
- Reformation and Early Modern Christianity
- Frailty in Older Adults
- Historical Economic and Social Studies
- Health disparities and outcomes
- Physical Activity and Health
- Scottish History and National Identity
- Diabetes Treatment and Management
- Obstructive Sleep Apnea Research
- Cardiovascular Health and Risk Factors
Finnish Institute for Health and Welfare
2016-2025
University of Helsinki
2003-2024
University of Gothenburg
2002-2023
Karolinska Institutet
2010-2023
Post Graduate Institute of Medical Education and Research
2022
Creative Research Enterprises (United States)
2022
Bayer (Germany)
2022
Ludwig-Maximilians-Universität München
2022
Zimmer Biomet (Germany)
2022
Hospital District of Helsinki and Uusimaa
2021
Weight loss is associated with short-term amelioration and prevention of metabolic cardiovascular risk, but whether these benefits persist over time unknown.
Obesity is a risk factor for cardiovascular events. Weight loss might protect against events, but solid evidence lacking.To study the association between bariatric surgery, weight loss, and events.The Swedish Obese Subjects (SOS) an ongoing, nonrandomized, prospective, controlled conducted at 25 public surgical departments 480 primary health care centers in Sweden of 2010 obese participants who underwent surgery 2037 contemporaneously matched controls received usual care. Patients were...
Short-term studies show that bariatric surgery causes remission of diabetes. The long-term outcomes for and diabetes-related complications are not known.To determine the diabetes rates cumulative incidence microvascular macrovascular after surgery.The Swedish Obese Subjects (SOS) is a prospective matched cohort study conducted at 25 surgical departments 480 primary health care centers in Sweden. Of patients recruited between September 1, 1987, January 31, 2001, 260 2037 control 343 2010 had...
Weight loss protects against type 2 diabetes but is hard to maintain with behavioral modification alone. In an analysis of data from a nonrandomized, prospective, controlled study, we examined the effects bariatric surgery on prevention diabetes.In this analysis, included 1658 patients who underwent and 1771 obese matched controls (with matching performed group, rather than individual, level). None participants had at baseline. Patients in bariatric-surgery cohort banding (19%), vertical...
Background In the late 1960s, coronary heart disease (CHD) mortality among Finnish men was highest in world. From 1972 to 2007, risk factor surveys have been carried out monitor trends and assess their contribution declining Finland. Methods The first survey North Karelia Kuopio provinces as basis for evaluation of Project. Since then, up five geographical areas included surveys. target population has persons aged 25–74 years, except two where sample drawn from a 30–59 years. Risk on change...
Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) is a multi-center, randomized, controlled trial ongoing in Finland.Participants (1200 individuals at risk of cognitive decline) are recruited from previous population-based non-intervention studies. Inclusion criteria CAIDE Dementia Risk Score ≥6 performance the mean level or slightly lower than expected for age (but not substantial impairment) assessed with Consortium Establish Registry Alzheimer's...
The prevalence and socioeconomic burden of type 2 diabetes (T2DM) associated co-morbidities are rising worldwide.This guideline provides evidence-based recommendations for preventing T2DM.A European multidisciplinary consortium systematically reviewed the evidence on effectiveness screening interventions T2DM prevention using SIGN criteria.Obesity sedentary lifestyle main modifiable risk factors. Age ethnicity non-modifiable Case-finding should follow a step-wise procedure questionnaires...
<b>Objective:</b> To investigate the relation of diabetes to dementia, Alzheimer disease (AD), and vascular dementia (VaD), through analyses incidence, mortality, neuropathologic outcomes in a prospective population-based study oldest old. <b>Methods:</b> The Vantaa 85+ included 553 residents living city Vantaa, Finland, aged ≥85 years on April 1, 1991. Survivors were reexamined 1994, 1996, 1999, 2001. Autopsies performed 291 persons who died during follow-up (48% total population). Diabetes...
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Obesity shortens life expectancy. Bariatric surgery is known to reduce the long-term relative risk of death, but its effect on expectancy unclear.We used Gompertz proportional hazards regression model compare mortality and among patients treated with either bariatric (surgery group) or usual obesity care (control in prospective, controlled Swedish Obese Subjects (SOS) study participants SOS reference (reference cohort), a random sample from general population.In total, 2007 2040 were...
Abstract Reducing the risk of dementia can halt worldwide increase affected people. The multifactorial and heterogeneous nature late‐onset dementia, including Alzheimer's disease (AD), indicates a potential impact multidomain lifestyle interventions on reduction. positive results landmark Finnish Geriatric Intervention Study to Prevent Cognitive Impairment Disability (FINGER) support such an approach. World‐Wide FINGERS (WW‐FINGERS), launched in 2017 over 25 countries, is first global...
In this study, the authors analyzed whether chronotypes, sleep duration, and sufficiency are associated with cardiovascular diseases type 2 diabetes by using National FINRISK Study 2007 data (N = 6258), being a representative sample of population aged 25 to 74 living in five areas Finland. Health status assessments laboratory measurements from participants 4589) DILGOM substudy were used for detailed analysis chronotype. Evening types had 2.5-fold odds ratio (p < .01) as compared morning...
Abstract Introduction The 2‐year Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) multidomain lifestyle intervention trial (NCT01041989) demonstrated beneficial effects on cognition. We investigated whether sociodemographics, socioeconomic status, baseline cognition, or cardiovascular factors influenced Methods FINGER recruited 1260 people from the general population (60–77 years, at risk for dementia). Participants were randomized 1:1 (diet,...
OBJECTIVE To investigate 1-year outcomes of a national diabetes prevention program in Finland. RESEARCH DESIGN AND METHODS Altogether 10,149 individuals at high risk for were identified with the Finnish Diabetes Risk Score (FINDRISC; scoring ≥15 points), by history impaired fasting glucose (IFG) or tolerance (IGT), cardiovascular disease, gestational mellitus 400 primary health care centers. One-year follow-up data available 2,798 participants who nondiabetic baseline (919 men and 1,879...
Individuals show variation in their preference for the daily timing of activities. In this study authors analyzed whether chronotypes associate with sleep duration and sleep-related complaints. The used National FINRISK Study 2007 Survey data on 3696 women 3162 men, representative Finnish population aged 25 yrs older, assessment chronotype self-reported sleep. Evening types experienced insomnia symptoms, had nightmares, recently hypnotics significantly more often than other among both men...