A5044865490- Maternal Mental Health During Pregnancy and Postpartum
- Pregnancy and Medication Impact
- Pregnancy and preeclampsia studies
- Attention Deficit Hyperactivity Disorder
- Pharmacological Effects and Toxicity Studies
- Birth, Development, and Health
- Child and Adolescent Psychosocial and Emotional Development
- Pharmaceutical studies and practices
- Cardiovascular Issues in Pregnancy
- Pharmaceutical Practices and Patient Outcomes
- Gestational Diabetes Research and Management
- Health Systems, Economic Evaluations, Quality of Life
- Asthma and respiratory diseases
- Prenatal Substance Exposure Effects
- Cancer Risks and Factors
- Opioid Use Disorder Treatment
- Chromosomal and Genetic Variations
- Respiratory and Cough-Related Research
- Pharmaceutical Economics and Policy
- Diabetes Treatment and Management
- RNA Interference and Gene Delivery
- Bipolar Disorder and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Schizophrenia research and treatment
- Adolescent and Pediatric Healthcare
Norwegian Institute of Public Health
2016-2025
Nasjonalforeningen for Folkehelsen
2005-2025
Institute of Public Health Zadar
2024
Karolinska Institutet
2013-2024
Brigham and Women's Hospital
2023
University of Bergen
2010-2023
Oslo University Hospital
2010-2023
Genetic Analysis (Norway)
2022-2023
OsloMet – Oslo Metropolitan University
2015-2019
Karolinska University Hospital
2013-2017
During the 2009 influenza A (H1N1) pandemic, pregnant women were at risk for severe illness. This concern was complicated by questions about vaccine safety in that raised anecdotal reports of fetal deaths after vaccination.We explored vaccination linking Norwegian national registries and medical consultation data to determine diagnosis, status, birth outcomes, background information before, during, pandemic. We used Cox regression models estimate hazard ratios death, with gestational day as...
<b>Objective</b> To assess whether maternal use of selective serotonin reuptake inhibitors (SSRIs) increases the risk persistent pulmonary hypertension in newborn, and such an effect might differ between specific SSRIs. <b>Design</b> Population based cohort study using data from national health registers. <b>Setting</b> Denmark, Finland, Iceland, Norway, Sweden, 1996-2007. <b>Participants</b> More than 1.6 million infants born after gestational week 33. <b>Main outcome measures</b> Risks...
Objective There is some evidence that clozapine significantly underutilised. Also, use thought to vary by country, but so far no international study has assessed trends in prescribing. Therefore, this aimed assess on an scale, using standardised criteria for data analysis. Method A repeated cross‐sectional design was applied extracts (2005–2014) from 17 countries worldwide. Results In 2014, overall prevalence greatest Finland (189.2/100 000 persons) and New Zealand (116.3/100 000), lowest...
<h3>Importance</h3> Women with epilepsy frequently need antiseizure medication (ASM) to prevent seizures in pregnancy. Risk of neurodevelopmental disorders after prenatal exposure AMSs is uncertain. <h3>Objective</h3> To determine whether children exposed prenatally ASMs monotherapy and duotherapy have increased risk disorders. <h3>Design, Setting, Participants</h3> The Nordic register-based study antiepileptic drugs pregnancy (SCAN-AED) a population-based cohort using health register social...
Prenatal antiseizure medication (ASM) exposure has been associated with adverse early neurodevelopment, but associations a wider range of psychiatric end points have not studied.
Importance Increasing use of second-line noninsulin antidiabetic medication (ADM) in pregnant individuals with type 2 diabetes (T2D) may result fetal exposure, but their teratogenic risk is unknown. Objective To evaluate periconceptional ADMs and whether it associated increased major congenital malformations (MCMs) the infant. Design, Setting, Participants This observational population-based cohort study used data from 4 Nordic countries (2009-2020), US MarketScan Database (2012-2021),...
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Mothers are using medicines during pregnancies; the extent varies across world and is generally difficult to compare. In this registry‐based study, we examined more than 100 000 Norwegian pregnancies described drug prescription pattern of both fathers mothers around conception pregnancy (mothers). STUDY ADDS every trimester pregnancy, about 30% was dispensed a drug. The total exposure did not seem diminish throughout pregnancy. One‐quarter drugs...
<b>Objective</b> To assess whether use of specific selective serotonin reuptake inhibitors (SSRIs) or venlafaxine in early pregnancy is associated with an increased risk birth defects, emphasis on cardiovascular defects even when accounting for lifestyle other familial confounding. <b>Design</b> Multicountry population based cohort study, including sibling controlled design. <b>Setting</b> Nordic (Denmark, Finland, Iceland, Norway, and Sweden) identified from nationwide health registers at...
BackgroundPrenatal inflammatory mechanisms may play a role in the pathogenesis of psychiatric disorders and could be relevant for attention-deficit/hyperactivity disorder (ADHD). We investigated maternal chronic somatic diseases with immune components as possible risk factors ADHD offspring.MethodsWe performed population-based nested case-control study by linking data from longitudinal Norwegian registers. included all individuals born during period 1967–2008 alive at record linkage (2012)....
Objectives: To give an overview of the data collection and content Norwegian Prescription Database (NorPD). In addition, key figures results from different studies using NorPD are presented. Methods: From 1st January 2004 Institute Public Health receives monthly on prescriptions dispensed collected at all pharmacies. Results: Overall, during four year period (2004-2007) over 4.2 million unique individuals have been recorded in with least one prescription medication a pharmacy. each about...
Given the rapidly increasing use of stimulant medications during pregnancy and among women reproductive age who may become pregnant inadvertently, there is a need to better understand their safety.To examine risk congenital malformations associated with intrauterine exposure stimulants.Cohort study Medicaid-insured population in United States nested 2000-2013 US Medicaid Analytic eXtract, follow-up safety signals detected eXtract data using Nordic Health registries (2003-2013) (Denmark,...
Background The purpose was to describe utilization of selective serotonin reuptake inhibitors (SSRIs) and serotonin–norepinephrine (SNRIs), including trends in prevalence, characteristics users, drug switching changes prescribed doses a large group pregnant women across four Nordic countries. Methods A study based on linked individual-level data from the nationwide prescription- medical birth registers Denmark, Iceland, Norway Sweden. population comprised all pregnancies these countries,...
Zoëga H, Furu K, Halldórsson M, Thomsen PH, Sourander A, Martikainen JE. Use of ADHD drugs in the Nordic countries: a population-based comparison study. Objective: To compare national use attention-deficit/hyperactivity disorder (ADHD) between five countries. Method: A drug utilisation study based on nationwide prescription databases, covering total 24 919 145 individuals 2007. defined according to World Health Organization Anatomic Therapeutic Chemical classification system as centrally...
Objectives: To study (i) the drug utilization pattern of anti-rheumatic drugs in pregnant women and expectant fathers (ii) association between use during pregnancy risk congenital malformations.Method: Pregnancies registered Medical Birth Registry Norway (MBRN) were linked to Norwegian Prescription Database (NorPD) period 2004–2007. Prescriptions for issued 3 months prior men conception identified. Congenital malformations recorded according European Surveillance Anomalies (EUROCAT)...
Maternal psychiatric disease is associated with adverse pregnancy outcomes. Use of selective serotonin reuptake inhibitors (SSRIs) during has been congenital anomalies, neonatal withdrawal syndrome, and persistent pulmonary hypertension the newborn. However, risk stillbirth infant mortality when accounting for previous maternal remains unknown.To study use SSRIs pregnancy.Population-based cohort from all Nordic countries (Denmark, Finland, Iceland, Norway, Sweden) at different periods 1996...
Background: β-Blockers are a class of antihypertensive medications that commonly used in pregnancy. Objective: To estimate the risks for major congenital malformations associated with first-trimester exposure to β-blockers. Design: Cohort study. Setting: Health registries 5 Nordic countries and U.S. Medicaid database. Patients: Pregnant women diagnosis hypertension their offspring. Measurements: First-trimester β-blockers was assessed. Outcomes were any malformation, cardiac malformations,...
Abstract Background: Long-term safety of assisted reproductive techniques (ART) is interest as their use increasing. Cancer risk known to be affected by parity. This study examined the cancer after fertility treatment, stratified women's Methods: Data were obtained from all women (n = 1,353,724) born in Norway between 1960 and 1996. Drug exposure data (2004–2014) Norwegian Prescription Database (drugs used ART clomiphene citrate). The Medical Birth Registry provided parity status. HRs...
To explore trends in use of maternal medication 3 months prior to, during and after pregnancy.Data on births from the Medical Birth Registry Norway were linked to Norwegian Prescription Database, identifying women's medications around pregnancy. All women giving birth 2005 2015 (638 532 singleton 414 567 women) included. Proportions pregnant using different association with pregnancy, annual relative change 2015, calculated.In Norway, 60% used prescription pregnancy (2005-15), increasing 57%...