A5012802109- Molecular Sensors and Ion Detection
- Nanoparticle-Based Drug Delivery
- Quantum Dots Synthesis And Properties
- Luminescence and Fluorescent Materials
- Advanced Nanomaterials in Catalysis
- Advanced biosensing and bioanalysis techniques
- Nanoplatforms for cancer theranostics
- Electrochemical Analysis and Applications
- Electrospun Nanofibers in Biomedical Applications
- Luminescence Properties of Advanced Materials
- Intraperitoneal and Appendiceal Malignancies
- Microfluidic and Capillary Electrophoresis Applications
- Cancer Research and Treatments
- Coconut Research and Applications
- Sulfur Compounds in Biology
- Ionic liquids properties and applications
- Gold and Silver Nanoparticles Synthesis and Applications
- thermodynamics and calorimetric analyses
- Nanoparticles: synthesis and applications
- Electrochemical sensors and biosensors
- bioluminescence and chemiluminescence research
- Antimicrobial agents and applications
- Neutropenia and Cancer Infections
- Analytical Chemistry and Chromatography
- Microbial Inactivation Methods
Universidade Nova de Lisboa
2018-2023
Rede de Química e Tecnologia
2018-2023
University of Lisbon
2020
Associação Científica Proteomass
2018
Luminescent mesoporous silica nanoparticles, CdTeQDs@MNs@PEG1, SiQDs@Isoc@MNs and SiQDs@Isoc@MNs@PEG2, were successfully synthetized characterized by SEM, TEM, XRD, N₂ nitrogen isotherms, ¹H NMR, IR, absorption, emission spectroscopy. Cytotoxic evaluation of these nanoparticles was performed in relevant vitro cell models, such as human hepatoma HepG2, brain endothelial (hCMEC/D3), epithelial colorectal adenocarcinoma (Caco-2) lines. None the tested showed significant cytotoxicity any three...
Abstract The rising of multidrug‐resistant bacteria and their associated proliferation as harmful microorganisms boosts the creation new antibacterial surfaces biomaterials with applications ranging from health to food packing. Herein, low‐cost PVA:PVP copolymers containing cyanine derivatives (1, 2, 3) respective Cu 2+ complexes are successfully obtained tested against Gram‐negative Gram‐positive bacteria. possible application in packing is addressed by covering surface typical paper...
Cyanine derivatives 1–3 were successfully characterized and their sensorial ability studied against Zn2+, Co2+, Cd2+, Ni2+, Cu2+, Hg2+ Ag+ metal ions. All dyes revealed a colourimetric selectivity towards Cu2+ ions, with the formation of mononuclear species. 2 can detect quantify lowest concentrations in aqueous media, 0.3 0.6 μM. With aim exploring optical properties these dyes, solid-supported devices designed by synthesis polymethylmethacrylate (PMMA) polymers doped 1, 2, 3 copper...
Cancer-related opportunistic bacterial infections are one major barrier for successful clinical therapies, often correlated to the production of genotoxic factors and higher cancer incidence. Although dual anticancer antimicrobial therapies a growing therapeutic fashion, they still fall short when it comes specific delivery local action in vivo systems. Nanoparticles seen as potential vectors, be by means their intrinsic antibacterial properties effective capacity, or repeatedly reported...
The need for non-invasive therapies capable of conserving drug efficiency and stability while having specific targetability against colorectal cancer (CRC), has made nanoparticles preferable vehicles principal building blocks the development complex multi-action anti-tumoral approaches. For that purpose, we herein report production a combinatory nanotherapy using new targeting towards CRC lines. To do so, Magneto-fluorescent NANO3 were used as nanocarriers combination drugs doxorubicin (DOX)...
The use of nanoparticles in multiple industries has raised concerned voices about the assessment their toxicity/antimicrobial activity and development standardized handling protocols. Issues emerge during antimicrobial assaying cargo, colorimetric, colloidal nanoformulations, as standard protocols often rely on visual evaluations, or optical density (OD) measurements, leading to high variance inhibitory concentrations (MIC). Thus, a fast, luminescence-based assay for effective is herein...
A NIR cyanine@imidazole derivative Cy1 was synthesized and evaluated as a metal ion sensor in solution. shown to be very sensitive all ions tested, presenting blue shift the absorption from 668 nm 633 nm, followed by change colour pale green with Zn2+, Cd2+, Co2+, Ni2+ Hg2+ ions. Despite absorption, decrease at (with colourless), well quenching emission intensity 785 were observed for Cu2+ The results show formation of sandwich complexes two ligands per highest association constant (Log...