A5008541221- Nanoplatforms for cancer theranostics
- MXene and MAX Phase Materials
- Gas Sensing Nanomaterials and Sensors
- Advanced biosensing and bioanalysis techniques
- Advanced Sensor and Energy Harvesting Materials
- Chemokine receptors and signaling
- Electrospun Nanofibers in Biomedical Applications
- Transition Metal Oxide Nanomaterials
- Conducting polymers and applications
- Advanced Nanomaterials in Catalysis
- Immunotherapy and Immune Responses
- Luminescence and Fluorescent Materials
- Nanoparticle-Based Drug Delivery
- Bone Metabolism and Diseases
- Material Properties and Applications
- Advancements in Solid Oxide Fuel Cells
- Polydiacetylene-based materials and applications
- Analytical Chemistry and Sensors
- ZnO doping and properties
- 2D Materials and Applications
- Nanocluster Synthesis and Applications
- Silicon Nanostructures and Photoluminescence
- Minerals Flotation and Separation Techniques
- Adenosine and Purinergic Signaling
- Antimicrobial Peptides and Activities
Ocean University of China
2023-2024
Beijing Institute of Fashion Technology
2023
Qingdao Agricultural University
2021-2023
Southwest University of Science and Technology
2021-2023
Hebei General Hospital
2007
Second Hospital of Hebei Medical University
2007
Fourth Hospital of Hebei Medical University
2007
Hebei Medical University
2007
Lac Courte Oreilles Ojibwa Community College
2007
Abstract Intracellular zinc ion (Zn 2+ ) accumulation disrupts the Zn homeostasis, providing an ion‐overloading anticancer strategy with great potential. The self‐adaptation of tumor cells to concentration, however, puts forward higher requirements for design strategy. Herein, “block and attack” antitumor was applied through a composite nanomaterials (UHSsPZH NPs). demonstrated powerful interference ability both “blocking” efflux excess via gene silencing “attacking” target delivery ZnO 2 ....
CMH-OBN nano-platform was designed for the ROS/GSH dual-responsive release of nitric oxide at tumor site realizing multi-modal therapy.
Ferric phosphate (FePOs) nanoenzymes can express peroxidase (POD) activity under the dual stimulation of an acidic environment and high H2O2 concentrations. In living organisms, this generates reactive oxygen species (ROS) in sites lesion infection, thus FePOs act as antimicrobial agents. Here, CeO2 ZnO2 were immobilized a scallop-type nanoenzyme material loaded with photosensitizer, indocyanine green, to synthesize multifunctional cascade nanoparticle system (FePOs-CeO2-ZnO2-ICG, FCZI NPs)....
Abstract Dysfunction of the calcium balancing system and disruption distribution can induce abnormal intracellular overload, further causing serious damage even cell death, which provides a potential therapeutic approach for tumor treatment. Herein, nano‐platform, includes UCNPs‐Ce6@RuR@mSiO 2 @PL‐HA NPs (UCRSPH) SA‐CaO nanoparticles, is prepared improving micro‐environment (TME), Ca 2+ signal disturbance as well enhanced photodynamic therapy (PDT). UCRSPH combined with alter TME relieve...
Abstract Current treatment of postmenopausal osteoporosis (PMOP) focuses on systemic administration medication, neglecting to proactively modulate the local microenvironment skeletal system for superior therapeutic performance. Eldecalcitol (ED‐71), a novel drug treating osteoporosis, still requires research overcome high‐frequency delivery and low‐utilization. Here, bone‐targeting multishelled nanoparticles are developed step‐wise release ED‐71. The achieved by using chitosan/alginate outer...
Ion interference therapy (IIT) is a promising cancer treatment strategy that can reverse ion distribution via bioactive nanomaterials so as to interfere with or hinder the physiological processes such metabolism and proliferation of tumor cells. In this study, dendritic Cu2+-doped calcium silicate nanosphere (Ca2SiO4) loaded ruthenium red (RuR) disulfiram (DSF) (RD-CCP) was constructed for self-enhanced chemodynamic IIT tumors through combination Cu Ca. Under slightly acidic environment...
In a previous study, we have verified that CXCR4 expression is correlated with tumor aggressive progression and poor prognosis in patients epithelial ovarian cancer. The aim of this study was to explore the effect CXCL12-CXCR4 axis on metastasis human cancer.The expressions CXCL12 mRNA protein cancer cell line CAOV-3 detected by RT-PCR immunocytochemistry. Methythiazolyltetrazolium (MTT) used analyze different concentrations proliferation cells. Transwell invasion chamber matrigel were...
During rapid proliferation and metabolism, tumor cells show a high dependence on methionine. The deficiency of methionine exhibits significant inhibition growth, which provides potential therapeutic target in therapy. Herein, ClO2-loaded nanoparticles (fluvastatin sodium&metformin&bupivacaine&ClO2@CaSiO3@MnO2-arginine-glycine-aspatic acid (RGD) (MFBC@CMR) NPs) were prepared for synergistic chlorine treatment methionine-depletion starvation After outer layer MnO2 was degraded the glutathione...
Single crystalline CdCO3 low-dimensional nanostructures, such as nanowires, nanobelts, and nanorolls have been controlled synthesized through a convenient, low-temperature hydrothermal method. Moreover, the shape diameter of nanostructures can be facilely adjusting experiment factors. The influences ammonia concentration temperature on morphology are investigated, possible mechanism involved adjustable growth properties from kinetic stage to thermodynamic has discussed. This work also...
Flexible capacitive pressure sensors as one of the crucial sensing components have aroused widespread concern because their vital role in development wearable artificial devices, healthcare biomonitoring and human-machine interface. However, there has been a considerable challenge to successfully fabricate them with tradeoff between high sensitivity large range by low-cost convenient manufacturing methods. Herein, orientated thermoplastic polyurethane elastomer rubber nanofiber membranes...
Oxygen sensors based on YSZ solid electrolyte thin films have great application prospects due to their advantages in miniaturization and integration. Here, we report the gas sensing performance of Pt/YSZ/Pt oxygen with low preparing temperatures. (200) preferred orientation been prepared by room temperature RF magnetron sputtering combined annealing at a 650 °C. The 700 nm-thick exhibit an obvious limiting current platform, IL shows linear dependence concentration X(O2) (in range 6%–21%)....