A5056212142- Leprosy Research and Treatment
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Blood groups and transfusion
- Hematological disorders and diagnostics
- Trypanosoma species research and implications
- Biochemical and Molecular Research
- Pharmacological Effects of Natural Compounds
- Health and Medical Education
- Pneumonia and Respiratory Infections
- Research on Leishmaniasis Studies
- Cancer Research and Treatments
- Hepatitis B Virus Studies
- Antifungal resistance and susceptibility
- Erythrocyte Function and Pathophysiology
- vaccines and immunoinformatics approaches
Instituto Médico La Floresta
2023
Corporación para Investigaciones Biológicas
2014
Central University of Venezuela
2003-2012
Ministerio del Poder Popular para la Educación Universitaria, Ciencia y Tecnología
2010-2012
Hospital Vargas
1987-2012
Leprosy is a slowly evolving disease that occurs mainly in adults. In this study, the Mamaría Village, state of Portuguesa was selected because it had one highest prevalence rates (13.25%) leprosy cases 1997. Between 1998-2004, 20.2% 89 registered village were less than 15 years old and 61.8% males. Pau-cibacillary (PB) lesions predominant clinical forms identified, although also multibacillary (MB) found. Additionally, 76% patients bacteriologically negative. At time diagnosis, 75%...
The goal of this study was to demonstrate the usefulness an enzyme-linked immunosorbent assay (ELISA) for serodiagnosis pulmonary tuberculosis (PTB) and extrapulmonary TB (EPTB). This used 20 amino acid-long, non-overlapped synthetic peptides that spanned complete Mycobacterium ESAT-6 Ag85A sequences. validation cohort consisted 1,102 individuals who were grouped into following five diagnostic groups: 455 patients with PTB, 60 EPTB, 40 non-EPTB, 33 leprosy 514 healthy controls. For PTB...
In this study, we measured gamma interferon production in mononuclear cell cultures from patients with diverse forms of leprosy and American cutaneous leishmaniasis. We studied lepromatous, borderline borderline, tuberculoid leprosy, as well a Mitsuda-negative contact. leishmaniasis localized cutaneous, mucocutaneous, diffuse the disease. High correlation was observed between lymphocyte proliferation assays both diseases. Resistant diseases showed significant reactivity, while severe...
Abstract Background Leprosy is a chronic infectious disease produced by Mycobacterium leprae . In 1997 Venezuela reached the goal of elimination leprosy as public health problem (according to World Health Organization prevalence rate ≤1/10,000 inhabitants), but five states still had rates over that goal. For this study we selected Cojedes State, where remain Objective Evaluate real situation in high‐prevalence areas State. Materials and methods Seven communities State were because they...
Leprosy is a neglected tropical disease that leads to physical disability and social discrimination. The active surveillance of new cases vigilance for drug resistance can decrease the incidence, improve clinical outcomes people affected by it. We analyzed, with molecular biology techniques, set skin biopsy samples from 25 Venezuelan patients. patients had been diagnosed leprosy in 2014 early 2015, 15 were relapse cases. tested dapsone, rifampicin, fluoroquinolones. In addition, we performed...
Leprosy is a stigmatising disease that remains public health problem in the Americas, Asia and Africa. To gain insight as to extent of Venezuela, we conducted cross sectional study 57 leprosy patients who attended specialised clinic at Institute Biomedicine Dr. Jacinto Convit, Caracas. The majority presented with five or more lesions time diagnosis, most commonly observed clinical lesion being nodules (in 66.7% patients), followed by maculae (36.8%), papules plaques (each 28.1%). Following...