A5006011739- Congenital Heart Disease Studies
- Cardiac Ischemia and Reperfusion
- Mechanical Circulatory Support Devices
- Transplantation: Methods and Outcomes
- Cardiac and Coronary Surgery Techniques
- Aortic Disease and Treatment Approaches
- Trauma Management and Diagnosis
- Cardiac Arrest and Resuscitation
- Surgical site infection prevention
- Vascular anomalies and interventions
- Aortic aneurysm repair treatments
- Restraint-Related Deaths
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Fuel Cells and Related Materials
- Cardiovascular Issues in Pregnancy
- Cardiac Structural Anomalies and Repair
- Mitochondrial Function and Pathology
- Cardiac Imaging and Diagnostics
- Surgical Sutures and Adhesives
- Esophageal and GI Pathology
- Reconstructive Surgery and Microvascular Techniques
- Pneumocystis jirovecii pneumonia detection and treatment
- Neutropenia and Cancer Infections
- Cardiovascular Function and Risk Factors
University Hospital of Bern
2014-2025
University of Bern
2015-2025
Abstract OBJECTIVES Donation after circulatory death provides excellent patient outcomes in heart transplantation; however, warm ischaemic graft damage remains a concern. We have reported that brief period of hypothermic oxygenated perfusion prior to normothermic reperfusion improves recovery rat model. Here we investigated the cardioprotective benefits and mechanisms this approach compared current clinical standard large animal METHODS Circulatory was induced anesthetized Male Schweizer...
To report our experience of late correction after infancy in patients with tetralogy Fallot (ToF).
We report a case of an infant surviving aortoesophageal fistula secondary to lithium cell battery ingestion. In the setting delayed vascular complication, computed tomography and magnetic resonance imaging are essential establishing correct diagnosis surgical management. Management children after ingestion must be guided by high index clinical suspicion.
The number of heart transplantations is limited by donor organ availability. Donation after circulatory determination death (DCDD) could significantly improve graft availability; however, organs undergo warm ischaemia followed reperfusion, leading to tissue damage. Laboratory studies suggest that mechanical postconditioning [(MPC); brief, intermittent periods at the onset reperfusion] can limit reperfusion injury; clinical translation has been disappointing. We hypothesized MPC-induced...
Minimal invasive extracorporeal circulation (MiECC) circuits are an established alternative to conventional (CECC). Based on the positive effects and improved perioperative outcomes of MiECC in adult cardiac surgery, this perfusion concept appears particularly attractive pediatric surgery. So far, there no reports clinical application a system for corrective surgery neonates children. We report our initial experiences by using surgery.A total 38 patients underwent surgical interventions...
Abstract Background This study evaluated the hemodynamic performance of arterial and venous cannulae in a compliant pediatric extracorporeal membrane oxygenation (ECMO) mock circuit pulsatile non‐pulsatile flow conditions. Methods The ECMO setup consisted an oxygenator, diagonal pump, standardized‐length arterial/venous tubing with pressure transducers. A validated left‐heart loop was adapted to simulate driven by computer‐controlled piston pump set at 120 bpm. roller used for primed 40%...
The study's aim was to investigate the outcomes and risk factors for mortality in patients undergoing surgery acute type A aortic dissection receiving concomitant venoarterial extracorporeal membrane oxygenation (ECMO) support. Patients from 5 European centre who underwent received perioperative ECMO support were included. multivariable binary logistic regression analysis performed identify 30-day mortality. receiver operating characteristic curve restricted cubic splines designed...
We report a case of child survival after extracorporeal membrane oxygenation (ECMO) support 25 days for cardiopulmonary failure and septic shock in the context juvenile myelomonocytic leukemia (JMML). ECMO is still matter debate management patients with malignancy. However, these are at increased risk early death secondary to pulmonary complications due leukostasis, direct infiltration WBC, systemic inflammatory response syndrome following malignant cell lysis. Despite high complications,...
Objectives: Rapidly occurring damage after warm ischaemia limits the potential of donation circulatory determination death (DCDD) for cardiac transplantation. Laboratory studies suggest that mechanical postconditioning (MPC) could prevent reperfusion injury; however, translation in humans has been disappointing. We hypothesised MPC effects on post-ischaemic haemodynamic recovery depend presence fatty acid solution. Methods: Isolated hearts male Wistar rats (n = 43) were perfused working mode...