A5068538390- Ovarian function and disorders
- Reproductive Biology and Fertility
- Transplantation: Methods and Outcomes
- Organ Transplantation Techniques and Outcomes
- Reproductive System and Pregnancy
- Renal Transplantation Outcomes and Treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Reproductive Health and Technologies
- Mechanical Circulatory Support Devices
- Fuel Cells and Related Materials
- Cardiac Ischemia and Reperfusion
- Endometriosis Research and Treatment
University Hospital of Bern
2022-2025
University of Bern
2024-2025
University Children’s Hospital Bern
2022
The advent of normothermic, ex-situ heart perfusion (ESHP) enables new options for evaluation cardiac grafts. Donation after circulatory death (DCD) is a promising solution to improve transplantation rates, but current ESHP approaches are recognized as suboptimal DCD We aimed develop vascular function test graft assessment during using porcine model DCD. Explanted hearts were perfused unloaded 3 hours followed by left ventricular loading 1 hour measure recovery. During perfusion, hypercapnic...
Abstract OBJECTIVES Donation after circulatory death provides excellent patient outcomes in heart transplantation; however, warm ischaemic graft damage remains a concern. We have reported that brief period of hypothermic oxygenated perfusion prior to normothermic reperfusion improves recovery rat model. Here we investigated the cardioprotective benefits and mechanisms this approach compared current clinical standard large animal METHODS Circulatory was induced anesthetized Male Schweizer...
Timing of ovulation triggering is essential in infertility treatments including based on natural menstrual cycles. However, data follicle size and oestradiol (E2) concentration are limited. Therefore, the model cycle IVF (NC-IVF) was applied to provide more detailed information these parameters better schedule optimal time for ovulation.A retrospective cross-sectional analysis 606 monofollicular NC-IVF cycles performed at a university-based centre from 2016 2019. Follicle E2 LH serum...
Does high-dose gonadotrophin stimulation have an effect on oocyte and early-stage embryo development?This was a retrospective study including 616 natural cycle IVF (NC-IVF) 167 conventional (cIVF) cycles. In total, 2110 oocytes were retrieved analysed in fresh NC-IVF, only human chorionic applied to trigger ovulation. cIVF, antagonist protocols with daily 150-300 IU of menopausal gonadotrophins performed. The development analysed. Primary outcomes the occurrence mature (metaphase II)...
It is known that Clomiphene citrate (CC) reduces endometrial thickness, but it unknown if additional gonadotrophin stimulation increases thickness and this has an effect on implantation rate in vitro fertilization (IVF). The retrospective study included 263 minimal IVF-cycles stimulated with 25 mg CC per day (CC-IVF), 161 plus 75IU hMG (human Menopausal Gonadotrophin) (CC/hMG-IVF). Endometrial oestradiol (E2) measurements were analysed between -4 0 (0 = of oocyte retrieval) the association...
Endometrial thickness <8 mm is related with lower pregnancy rates. This raises the question if endometrial can be increased by gonadotropin stimulation to increase estradiol (E2) concentration and such an artificial thickening of endometrium has effect on implantation. A model address this comparison outcome parameters in conventional stimulated IVF (cIVF) compared unstimulated natural cycle (NC-IVF).Retrospective study including 235 cIVF 616 NC-IVF cycles without embryo selection fresh...