Motoshi Takao

ORCID: 0000-0003-1305-8554
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About
Contact & Profiles
Research Areas
  • Lung Cancer Diagnosis and Treatment
  • Tracheal and airway disorders
  • Medical Imaging and Pathology Studies
  • Lung Cancer Treatments and Mutations
  • Cardiac Valve Diseases and Treatments
  • Myasthenia Gravis and Thymoma
  • Cardiac tumors and thrombi
  • Transplantation: Methods and Outcomes
  • Pleural and Pulmonary Diseases
  • Cancer Diagnosis and Treatment
  • Sarcoma Diagnosis and Treatment
  • Radiomics and Machine Learning in Medical Imaging
  • Congenital Diaphragmatic Hernia Studies
  • Cardiac and Coronary Surgery Techniques
  • Aortic Disease and Treatment Approaches
  • Pulmonary Hypertension Research and Treatments
  • Cardiac Structural Anomalies and Repair
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Metastasis and carcinoma case studies
  • Organ Transplantation Techniques and Outcomes
  • Cardiac Ischemia and Reperfusion
  • Mechanical Circulatory Support Devices
  • Lung Cancer Research Studies
  • Salivary Gland Tumors Diagnosis and Treatment
  • Catalytic Processes in Materials Science

Mie University
2016-2025

Mie University Hospital
2013-2024

Hokkaido University
2020-2023

McMaster University
2018

Saga University
2018

Mie Prefectural College Of Nursing
2013

University of Fukui
2005

Fukuoka University
1995-2004

RELX Group (Netherlands)
2004

Hy-Line (United States)
2004

The AE1 gene encodes band 3 Cl-/HCO3- exchangers that are expressed both in the erythrocyte and acid-secreting, type A intercalated cells of kidney. Kidney contributes to urinary acidification by providing major exit route for HCO3- across basolateral membrane. Several mutations cosegregate with dominantly transmitted nonsyndromic renal tubular acidosis (dRTA). However, modest degree vitro hypofunction exhibited these dRTA-associated fails explain disease phenotype light normal associated...

10.1172/jci4836 article EN Journal of Clinical Investigation 1998-12-15

Background Although radiofrequency ablation (RFA) is widely performed for the treatment of colorectal cancer (CRC) lung metastases, its efficacy candidates with surgically resectable disease unclear. Purpose To evaluate prognosis after RFA in participants CRC metastases. Materials and Methods For this prospective multicenter study (ClinicalTrials.gov identifier: NCT00776399), five or fewer metastases measuring 3 cm less were included. Participants a total 100 0.4-2.8 (mean, 1.0 ± 0.5) chosen...

10.1148/radiol.2020191272 article EN Radiology 2020-01-14

Abstract We have constructed and analyzed an updated dataset consisting of 4759 experimental datapoints for the oxidative coupling methane (OCM) reaction based on literature data reported before 2020 (∼2019) using machine learning (ML) methods. Several ML methods, including random forest regression (RFR), extra trees (ETR), gradient boosting with XGBoost (XGB), were used in conjunction our proposed approach, which elemental features are as input representations rather than inputting catalyst...

10.1002/cctc.202100495 article EN cc-by-nc ChemCatChem 2021-05-31

Background A better understanding of the tumor immune microenvironment (TIME) will facilitate development prognostic biomarkers and more effective therapeutic strategies in patients with lung cancer. However, little has been reported on comprehensive evaluation complex interactions among cancer cells, local immunosuppressive elements TIME. Methods Whole-exome sequencing RNA were carried out 113 cancers. We performed single sample gene set enrichment analysis TIME-related sets to develop a...

10.1136/jitc-2021-003765 article EN cc-by-nc Journal for ImmunoTherapy of Cancer 2022-04-01

Endothelium-derived nitric oxide (NO) is an important regulator of vascular resistance. Low concentrations NO have been recorded in the exhaled breath spontaneously breathing animals and humans. To determine whether synthesis lung contributes to measured breath, we concentration air isolated perfused ventilated porcine lungs by using a chemiluminescence method. With NO-free normoxic ventilation (21% O2–5% CO2–74% N2) eight with Krebs-dextran albumin perfusate, baseline was 5.8 +/- 1.8 parts...

10.1152/jappl.1995.78.1.59 article EN Journal of Applied Physiology 1995-01-01

<h3>Objective</h3> To compare prostacyclin with an analogue, iloprost, in treatment of severe pulmonary hypertension. <h3>Patients</h3> Eight patients hypertension: primary five, thromboembolic hypertension three. <h3>Methods</h3> All underwent right heart catheterisation. Mean (SEM) atrial pressure was 9.9 (2.2) mm Hg, mean artery 67.4 (3.0) cardiac index 1.75 (0.13) l/min/m<sup>2</sup> and mixed venous oxygen saturation 59.1(3.1)%. Continuous intravenous epoprostenol (prostacyclin,...

10.1136/hrt.79.2.175 article EN Heart 1998-02-01

Catalytic methylation of aromatic hydrocarbons using CO2 and H2 as a methylating agent was conducted over combination TiO2-supported Re (Re(1)/TiO2; = 1 wt %) H-β (SiO2/Al2O3 40) in batch reactor. m-xylene performed, this catalyst demonstrated excellent performance for the synthesis methylbenzenes, giving high yield total methylated products (10 57%, calculated on basis m-xylene, respectively), while generating relatively small amounts byproducts such demethylated dearomatized well CO CH4...

10.1021/acscatal.0c05661 article EN ACS Catalysis 2021-04-28

Designing novel catalysts is key to solving many energy and environmental challenges. Despite the promise that data science approaches, including machine learning (ML), can accelerate development of catalysts, truly have rarely been discovered through ML approaches because one its most common limitations criticisms-the assumed inability extrapolate identify extraordinary materials. Herein, we demonstrate an extrapolative approach develop new multi-elemental reverse water-gas shift catalysts....

10.1038/s41467-023-41341-3 article EN cc-by Nature Communications 2023-09-21

Although some retrospective studies have reported clinicopathological scoring systems for predicting postoperative complications and survival outcomes elderly lung cancer patients, optimized remain controversial.The Japanese Association Chest Surgery (JACS) conducted a nationwide multicentre prospective cohort enrolled total of 1019 octogenarians with medically operable cancer. Details the clinical factors, comorbidities comprehensive geriatric assessment were recorded 895 patients to...

10.1093/ejcts/ezx415 article EN European Journal of Cardio-Thoracic Surgery 2017-11-27

Chest radiography is a useful noninvasive modality to evaluate pulmonary blood flow status in patients with congenital heart disease. However, the predictive value of chest limited by subjective and qualitive nature interpretation. Recently, deep learning has been used analyze various images, but it not applied analyzing radiographs such patients.To develop validate quantitative method predict systemic ratio from using learning.This retrospective observational study included 1031 cardiac...

10.1001/jamacardio.2019.5620 article EN JAMA Cardiology 2020-01-22

Adsorption is a critical step in the initial stage of catalytic reaction. Oxygen vacancies often become central topic discussion with respect to reaction mechanism on metal oxide surfaces because oxygen change surface electronic properties and affect adsorption process. In this study, we use first-principles calculations regression analyses investigate effect small molecules. We adopt anatase (101) rutile (110) TiO2 as research targets. The calculation results show that removal an atom...

10.1021/acs.jpcc.0c09614 article EN The Journal of Physical Chemistry C 2021-02-09

Pulmonary enteric adenocarcinoma (PEAC) is an extremely rare subtype of non-small cell lung cancer, characterised by histopathological features that resemble colorectal adenocarcinoma. Here, we report a case PEAC in 85-year-old male who presented with pulmonary nodule initially identified at the age 76. Initial PET-CT (maximum standardised uptake value [SUVmax] = 2.8) was inconclusive, leading to strict follow-up. Over 9 years, enlarged significantly (3.2 cm, SUVmax 8.4). A transbronchial...

10.1002/rcr2.70127 article EN cc-by Respirology Case Reports 2025-02-01

The diagnostic performance of automated analysis electrocardiograms for screening children with pediatric heart diseases at risk sudden cardiac death is unknown. In this study, we aimed to develop and validate a deep learning-based model ECGs in children. Wave data 12-lead were transformed into tensor sizing 2 × 12 400 using signal processing methods. A classify abnormal based on age, sex, the wave was developed performed patients age 6-18 years during 2003-2006 tertiary referral hospital...

10.3389/fcvm.2025.1471989 article EN cc-by Frontiers in Cardiovascular Medicine 2025-03-05

Adsorption is an essential process that takes place in heterogeneous catalysis. In the current study, solid–adsorbate interactions occurring between a variety of small molecules and surfaces group 13 metal oxides, including β-Ga2O3(100), β-Ga2O3(001), θ-Al2O3(100), θ-Al2O3(001), θ-Al2O3(010), In2O3(110), In2O3(111), were investigated using density functional theory calculations machine learning (ML)-based statistical method. The adsorbates utilized for this purpose include CO, CO2, N2, NH3,...

10.1021/acs.jpcc.0c04480 article EN The Journal of Physical Chemistry C 2020-06-16

Metal/oxide support perimeter sites can provide unique properties because the local environment on surface is changed by nearby metal. This study modeled when metal nanorods were adsorbed in lieu of nanoparticles (111) an In2O3 support. The element M was one Ag, Au, Cu, Ir, Pd, Pt, and Re. Changes oxygen vacancy formation energy (EOvac) with nanorod adsorption evaluated using systematic first-principles calculations under same approximations conditions found to be driven two major factors....

10.1021/acs.jpcc.0c10010 article EN cc-by-nc-nd The Journal of Physical Chemistry C 2020-12-08
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