A5101886345- Diet, Metabolism, and Disease
- Adipokines, Inflammation, and Metabolic Diseases
- Microbial Community Ecology and Physiology
- Obesity, Physical Activity, Diet
- Regulation of Appetite and Obesity
- Vitamin D Research Studies
- MicroRNA in disease regulation
- Histone Deacetylase Inhibitors Research
- Epigenetics and DNA Methylation
- Anesthesia and Neurotoxicity Research
- Genetics and Physical Performance
- Retinoids in leukemia and cellular processes
- Posttraumatic Stress Disorder Research
- Obstructive Sleep Apnea Research
- Phytoestrogen effects and research
- Cardiovascular Disease and Adiposity
- Traumatic Brain Injury Research
- Genetic Mapping and Diversity in Plants and Animals
- Remote Sensing and Land Use
- Nutrition, Genetics, and Disease
- Apelin-related biomedical research
- Neurogenesis and neuroplasticity mechanisms
- Plant and animal studies
- Soil Carbon and Nitrogen Dynamics
- Adipose Tissue and Metabolism
State Forestry and Grassland Administration
2025
Chinese Academy of Sciences
2006-2025
Shandong Provincial Hospital
2025
Shandong University
2025
Sichuan Agricultural University
2025
Chengdu Institute of Biology
2025
Institute of Geographic Sciences and Natural Resources Research
2025
University of Chinese Academy of Sciences
2024-2025
Shandong Agricultural University
2025
Shanghai Institute of Nutrition and Health
2024
Abstract Histone lactylation plays a crucial role in cancer progression, but its impact on breast (BC) tumorigenesis is still unclear. We utilized chromatin immunoprecipitation sequencing with H3K18la antibodies, transcriptomics of clinical BC samples, and proteomics ATAC-seq analyses vivo tumors to identify the genes regulated by transcription factor PPARD. qPCR Western blot assays were used detect expressions molecules. discovered that levels higher tissues compared adjacent non-cancerous...
Introduction One of the central aims in ecology is elucidating mechanisms that shape community diversity. While biodiversity patterns across geographical gradients are often attributed both to local assembly processes and regional species pools, distinct roles these factors shaping soil aerobic methanotrophic diversity remain underexplored. Methods Using amplicon sequencing bioinformatics analysis, this study focuses on comparing relative importance pool communities three plateaus China:...
<title>Abstract</title> Alkaline phosphatase gene (<italic>phoD</italic>) harboring microbial communities drive organic phosphorus (P) mineralization, regulating plant P availability and ecosystem productivity. However, their global distribution pattern, key environmental drivers, responses to climate change remain poorly understood. Here, we conducted a meta-analysis of <italic>phoD</italic> amplicon sequences from 3,175 samples spanning diverse ecosystems worldwide, revealing higher...
As a pivotal region for safeguarding China’s food security, Northeast China requires quantitative evaluation of crop yield dynamics, planting structure shifts, and their interdependent mechanisms. Leveraging MODIS NPP data remote sensing-derived classification from 2001 to 2021, this study established estimation model. By integrating the Theil–Sen median slope estimator Mann–Kendall trend analysis, we systematically investigated spatiotemporal characteristics maize, rice, soybean yields....
The Asian larch bark beetle, I. subelongatus Motschulsky, is a severe pest of various Larix species in its natural range. This study reports the degree similarity among cuticular hydrocarbon (CHC) profiles six populations northeastern China. Thirty individual or isomeric mixtures hydrocarbons were identified by solid-phase microextraction (SPME) coupled with gas chromatography–mass spectrometry (GC–MS). components consist straight-chain alkanes, alkenes, and methyl-branched carbon chain...
Objective: To explore hippocampal structural abnormalities in fire victims with recent-onset posttraumatic stress disorder (PTSD). Method: We compared 12 patients PTSD diagnosed according to DSM-IV criteria 6 8 months after a major individuals without who were of the same accident. Voxel-based morphometry (VBM) and magnetic resonance spectroscopy (MRS) combined examine PTSD. Results: Results VBM showed that grey matter density left hippocampus was lower group than it MRS ratio N-acetyl...
Background/Objectives Recent large-scale genome-wide association studies have identified multiple loci robustly associated with BMI, predominantly in European ancestry (EA) populations. However, associations of these obesity and related traits not been well described Chinese Hans. This study aimed to investigate whether BMI-associated are, individually collectively, adiposity-related Hans are modified by physical activity (PA). Subjects/Methods We genotyped 28 single nucleotide polymorphisms...
Chronic low-grade inflammation and adipokines dysregulation are linked to mechanisms underscoring the pathogenesis of obesity-related metabolic disorders. Little is known about roles these cytokines on association between snoring syndrome (MetS). We aimed investigate whether a cluster related frequency its with MetS in apparently healthy Chinese.
The effects of (+) securinine on behavior and morphological changes after intracerebral ventricle injection beta-amyloid (25-35) (Abeta(25-35)) in rats were investigated. A single high dose Abeta(25-35) could impair the spatial cognitive function. latency locating platform was longer model group than sham-operated group. While chronic administration D-securinine (40 mg kg(-1)) significantly shorten latency. After Morris water maze, activity choline acetyltransferase (ChAT)...
Background: An imbalance between total training load and recovery may cause overtraining. The purpose of the present study was to verify effects overtraining on expression brain derived neuro¬trophic factor (BDNF), its receptor tropomyosin kinase B (TrkB) p75 dynamic patterns brain-specific miR-34a miR-124 or inflammation-related miR-21 miR-132 in mouse hippocampus. Method: 8 weeks old C57BL/6J mice were randomly assigned control (CON), normal (NT) (OT) groups. 8-week OT protocol applied...
Abstract High-volume training followed by inadequate recovery may cause overtraining. This process undermine the protective effect of regular exercise on cardiovascular system and increase risk pathological cardiac remodelling. We evaluated whether chronic overtraining changes cardiac-related microRNA profiles in left right ventricles. C57BL/6 mice were divided into control, normal training, overtrained running without inclination, uphill or downhill groups. After an 8-week treadmill...
Background : To investigate the effect of early losartan treatment on blood pressure and cardiac hypertrophy in adult spontaneously hypertensive rats, as well methylation promoters angiotensin II type 1 receptor (AT R) subtype b 1b AT R-associated protein (ATRAP) genes myocardium.Methods: Male offspring rats were randomly assigned to 4 groups: prenatal losartan-treated group, postnatal sequential untreated group.Systolic was measured by tail-cuff method, left ventricular mass/body mass...