A5114374018- Multiple Sclerosis Research Studies
- Genetics and Physical Performance
- Diabetes Management and Research
- Diabetes and associated disorders
- Muscle metabolism and nutrition
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Vitamin D Research Studies
- Molecular Biology Techniques and Applications
- Bone health and treatments
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Bone Metabolism and Diseases
- Exercise and Physiological Responses
- Hormonal and reproductive studies
- Folate and B Vitamins Research
- Multiple Myeloma Research and Treatments
- Chromosomal and Genetic Variations
- Cardiovascular and Diving-Related Complications
- Iron Metabolism and Disorders
- Forensic Toxicology and Drug Analysis
- RNA Research and Splicing
- Chemotherapy-induced cardiotoxicity and mitigation
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- High Altitude and Hypoxia
- Tryptophan and brain disorders
- Karst Systems and Hydrogeology
University of Rome Tor Vergata
1996-2020
Human endogenous retroviruses (HERVs) have been implicated in human physiology and pathology. A better knowledge of the retroviral transcriptional activity general population during life span would greatly help debate on its pathologic potential. The four HERV families (H, K, W, E) was assessed, by qualitative quantitative PCR, PBMCs from 261 individuals aged 1 to 80 years. Our results show that HERV-H, HERV-K, HERV-W, but not HERV-E, are transcriptionally active test already early...
Objectives. Several lines of evidences suggest that human endogenous retroviruses (HERVs) are implicated in the development many complex diseases with a multifactorial aetiology and strong heritability, such as neurological psychiatric diseases. Attention deficit hyperactivity Disorder (ADHD) is neurodevelopmental disorder results from interaction environmental, biological genetic factors. Our aim was to analyse expression levels three HERV families (HERV-H, K W) patients ADHD. Methods. The...
Background Glycated hemoglobin (HbA 1c ) provides a useful estimate of mean glycemia in patients with diabetes and is directly related to risks for complications. The aim this study compare capillary electrophoresis method two high‐performance liquid chromatography (HPLC) cation‐exchange analyzers (Variant II (Bio‐Rad Laboratories, Inc., Hercules, CA) G8 (Tosoh Biosciences, San Francisco, CA)) identify the most reliable Hb variants' presence. Methods Measurements HbA were carried out blood...
Objective: Pleural effusion is a common diagnostic problem and challenge to the thoracic surgeon. The analysis of serum body fluids for tumor markers an established procedure. Among various markers, tumors are linked overexpression glycolytic isoenzyme, M2-pyruvate-kinase (M2-PK). This preliminary study evaluated this enzyme as marker differentiate malignant from benign pleural effusion. Methods: M2-PK concentration was measured in EDTA-plasma fluid 34 patients with diagnosis cancer, either...
The present study examines the hypothesis that elevated levels of transforming growth factor (TGF)-beta1 and interleukin (IL)-10 would be protective for fetus survival during pregnancy-induced hypertension (PIH). Moreover, we evaluate IL-12 IL-15 serum concentrations their relationships with PIH.Serum samples were obtained before onset labor from control PIH groups. Cytokine determined by Enzyme-Linked Immunoadsorbent Assay.Our data show women have significantly higher TGF-beta1 IL-10...
Serum and urine free light chains (FLCs) monoclonal immunoglobulin (k λ) are important markers in the diagnosis monitoring of B cell proliferative disorders, such as Multiple Myeloma (MM), Monoclonal Gammopathy (MG), Undetermined Significance (MGUS), Amyloidosis (AL) related disorders (Bird et al, 2009; Kyle 2010). MM is a progressive neoplastic disease characterized by bone marrow plasmacytosis (plasma tumour) overproduction an intact (IgG, IgA, IgM, IgD or IgE) and/or Bence Jones protein....
The Pozzo del Merro (Merro sinkhole), a few kilometres away from Rome, Italy, is the deepest flooded karstic cavity known in world. Over last two years, multi-disciplinary scientific research project studied almost unknown aquatic ecosystem of the sinkhole while also studying psychological and physiological reactions of divers operating in the very hostile underwater environment. This paper presents preliminary overview seven studies carried out parallel and attempts to highlight...