A5054874494- Nerve injury and regeneration
- Nerve Injury and Rehabilitation
- Orthopedic Surgery and Rehabilitation
- Peripheral Nerve Disorders
- Botulinum Toxin and Related Neurological Disorders
- Pain Mechanisms and Treatments
- Neurogenesis and neuroplasticity mechanisms
- Effects of Vibration on Health
- Musculoskeletal pain and rehabilitation
- Dupuytren's Contracture and Treatments
- Tendon Structure and Treatment
- Elbow and Forearm Trauma Treatment
- Electrospun Nanofibers in Biomedical Applications
- Bone fractures and treatments
- Shoulder Injury and Treatment
- Tissue Engineering and Regenerative Medicine
- Congenital limb and hand anomalies
- Myofascial pain diagnosis and treatment
- Nail Diseases and Treatments
- Organ and Tissue Transplantation Research
- Medical Malpractice and Liability Issues
- Muscle activation and electromyography studies
- Neuroscience and Neural Engineering
- Diabetic Foot Ulcer Assessment and Management
- Balance, Gait, and Falls Prevention
Skåne University Hospital
2016-2025
Lund University
2016-2025
Linköping University
2002-2024
Sahlgrenska University Hospital
1983-2023
John Wiley & Sons (United States)
2022
Malmö University
2005-2020
National Center for Geriatrics and Gerontology
2013
Hässleholms Sjukhus
2011
Miami Hand Center
2008
Manchester Royal Infirmary
2008
The long-term outcome from silicone tube nerve repair was compared with the routine microsurgical in a clinical randomized prospective study, comprising 30 patients median or ulnar injuries distal forearm. Postoperatively, underwent neurophysiological and assessments of sensory motor function regularly over 5-year period. After 5 years there no significant difference between two techniques except that cold intolerance significantly less severe tubular technique. In total group ongoing...
The mechanisms influencing regeneration of peripheral nerves are incompletely known, but growth factors supposed to play a key role. In the present study, we demonstrate, with aid immunohistochemical methods, that somatomedin C (Sm‐C/insulin‐like factor I/IGF‐I) rapidly increased from low high concentrations, reaching peak values in 2 weeks, regenerating sciatic adult rats. addition, IGF‐I was demonstrated extracellularly, never observed control nerves. Reactive Schwann cells appeared be...
Biosynthetic nerve grafts are developed in order to complement or replace autologous for peripheral reconstruction. Artificial guides currently approved clinical use not widely applied reconstructive surgery as they still have limitations especially when it comes critical distance repair. Here we report a comprehensive analysis of fine-tuned chitosan (CNGs) enhanced by introduction longitudinal film reconstruct length 15 mm sciatic defects adult healthy Wistar diabetic Goto-Kakizaki rats....
Biosynthetic nerve grafts are desired as alternative to autologous in peripheral reconstruction.Artificial conduits still have their limitations and not widely accepted the clinical setting.Here we report an analysis of fine-tuned chitosan tubes used reconstruct 10 mm defects adult rat.The displayed low, medium high degrees acetylation (DAI: w2%, DA: w5%, DAIII: w20%) therefore different degradability microenvironments for regenerating tissue.Short long term investigations were performed...
To describe the principles, process, and results of creating International Consortium for Health Outcomes Measurement (ICHOM) standard set hand wrist conditions.Following standardized methods ICHOM, an international working group surgeons, therapists, researchers was assembled to develop evidence-based, patient-centered, outcome measures patients with conditions. Multiple systematic reviews were performed support our choices domains tools Fourteen video conferences held between March 2018...
Patients with injured hands and forearms of varying severity [Hand Injury Severity Score (HISS)] were studied prospectively, including analysis costs, hand/arm function (DASH), health status (SF-36). Costs, duration sick-leave, DASH-score (high score; impaired function) increased by injury (higher HISS) the greatest proportion total costs resulted from lost production. Most employed patients returned to work within a year, but even minor injuries expensive. HISS care during an emergency...
This study analysed the costs of median and ulnar nerve injuries in forearm humans factors affecting such costs. The within health-care sector lost production were calculated 69 patients with an injury to and/or forearm, usually caused by glass, a knife, or razorblade. Factors associated variation outcome analysed. total for employed person EUR 51,238 31,186, respectively, 87% due loss production. All higher concomitant tendon (4 tendons). also who changed work after if both nerves injured....
In the rat sciatic nerve, a gap of around 10 mm in nerve continuity seems to be maximal distance which can successfully repaired by silicone tubes. this study we tested if new artificial graft, composed eight polyamide filaments (diameter 250 μm) placed inside tubes (1.8 inner diameter), could used bridge an extended (15 mm) nerve. Silicone containing sutures were found support regeneration across such gap. After 4 weeks sensory fibres had bridged and grown into distal segment as revealed...
Compound action potentials of both myelinated (A) and non‐myelinated (C) fibres in the common peroneal nerve rabbits were studied during after acute, graded compression at 200 or 400 mmHg applied for 2 h ischaemia created by nitrogen inhalation aortic occlusion. Compression blocked Ai component (large fibres) about 23 min, while shortened this time to 11 min. The A2 (thinner had a lower conduction velocity higher resistance compression. There was just slight decrease nonmyelinated when...
The ulnar nerve of a 21-year old man was repaired at the wrist by silicone chamber technique 10 days after traumatic transection. A 3 mm gap left between ends inside chamber. At follow-up three years later, motor and sensory recovery excellent. exploration that time macro-scopically normal found in tube.
Transected median nerves in the forearm of two male patients, 12 and 21 years age, were treated with a chamber technique leaving 3 to 5 mm gap between nerve ends. The ends enclosed silicone tube such dimension that would not cause compression nerve. Post-operative examination including sensory evaluation assessment muscle contraction force was carried out after years. In both cases there excellent motor recovery thenar muscles. Outgrowth fibres remarkably fast, resulting ultimately...
Abstract Regeneration of severed peripheral nerves is unfortunately often incomplete, due to loss nerve fibers and neuroma formation. A new approach presented with the intention improving conditions for repair. In first two stages, a pseudosynovial tube formed around silicone rubber rod, surrounded by stainless steel spiral, which was placed in backs rats. This tube, second stage, used as free “tube graft” bridge gaps about 10–12‐mm lengths sciatic nerve. The kept open metal spiral....
Abstract Background To study costs and outcome for serious hand arm injuries during the first year after trauma. Methods In patients with a Hand Injury Severity Score (HISS) > 50, DASH EQ-5D scores as well factors related to within health care sector, due lost production total were evaluated. Cox-regression analysis stratifying mechanism of injury was used analyse return work. Results The majority 45 included (median 42 years 16–64) men severe (n = 9) or major 36) different type...