A5028758479- Chronic Kidney Disease and Diabetes
- Dialysis and Renal Disease Management
- Noise Effects and Management
- COVID-19 epidemiological studies
- Health disparities and outcomes
- Climate Change and Health Impacts
- Musculoskeletal pain and rehabilitation
- Renal Diseases and Glomerulopathies
- Air Quality and Health Impacts
- Advanced Causal Inference Techniques
- COVID-19 and healthcare impacts
- Urban Green Space and Health
- SARS-CoV-2 and COVID-19 Research
- Acute Kidney Injury Research
- Machine Learning in Healthcare
- Contact Dermatitis and Allergies
- Blood Pressure and Hypertension Studies
- Birth, Development, and Health
- ECG Monitoring and Analysis
- Acute Myocardial Infarction Research
- Vaccine Coverage and Hesitancy
- COVID-19 Clinical Research Studies
- Urban Transport and Accessibility
- Renal and Vascular Pathologies
- Statistical Methods and Bayesian Inference
Lund University
2016-2025
Skåne University Hospital
2016-2025
Indiana University – Purdue University Indianapolis
1990-2024
Halmstad University
2024
Materials Design (France)
2024
Karolinska University Hospital
2008-2023
Karolinska Institutet
2008-2023
KU Leuven
2023
University of Liège
2023
University Hospital of North Norway
2023
Serum creatinine is the most commonly used marker for estimation of glomerular filtration rate (GFR). To compensate its drawbacks as a GFR marker, several prediction equations including parameters are being used, with Modification Diet in Renal Disease (MDRD), Schwartz, and Counahan-Barratt ones widely accepted relative mL x min(-1) (1.73 m(2))(-1). The present study analyzes whether these adults children might be replaced by simple based on plasma concentrations cystatin C.Data from 536...
<h3>Objectives:</h3> The aim of this population-based study was to investigate associations between recreational values the close natural environment and neighbourhood satisfaction, physical activity, obesity wellbeing. <h3>Methods:</h3> Data from a large public health survey distributed as mailed questionnaire in suburban rural areas southern Sweden were used (N = 24 819; 59% participation rate). Geocoded residential addresses geographical information system technique assess objectively...
Many different cystatin C-based equations exist for estimating glomerular filtration rate. Major reasons this are the previous lack of an international C calibrator and nonequivalence results from assays.Use recently introduced certified reference material, ERM-DA471/IFCC, further work to achieve high agreement equivalence 7 commercially available assays allowed a substantial decrease CV assays, as defined by their performance in external quality assessment clinical laboratory...
Poor mental health is a major issue worldwide and causality complex. For diseases with multifactorial background synergistic effects of person- place- factors can potentially be preventive. Nature suggested as one such positive place-factor. In this cohort study we tested the effect defined green qualities (Serene, Space, Wild, Culture, Lush) in environment at baseline on follow-up. We also studied interaction those place varied person (financial stress, living conditions, physical...
The Chronic Kidney Disease in Children Study (CKiD) equation for children and the Epidemiology Collaboration (CKD-EPI) adults are recommended serum creatinine (SCr)-based calculations estimating glomerular filtration rate (GFR). However, these equations, as well their combination, have limitations, notably problem of implausible changes GFR during transition from adolescence to adulthood overestimation young adults. full age spectrum (FAS) addresses issues but overestimates when SCr levels...
The need for a mobile workforce inevitably means that the length of total work day (working and traveling time) will increase, but health effects commuting have been surprisingly little studied apart from perceived stress benefits physically active commuting. We used data two cross-sectional population-based public surveys performed in 2004 2008 Scania, Sweden (56% response rate). final study population was 21, 088 persons aged 18-65, working > 30 h/week. Duration (one-way) mode were...
A reliable assessment of glomerular filtration rate (GFR) is paramount importance in clinical practice as well epidemiological and research settings. It recommended by Kidney Disease: Improving Global Outcomes guidelines specific populations (anorectic, cirrhotic, obese, renal non-renal transplant patients) where estimation equations are unreliable. Measured GFR the only valuable test to confirm or confute status chronic kidney disease (CKD), evaluate slope function decay over time, assess...
While there is general agreement on the necessity to measure glomerular filtration rate (GFR) in many clinical situations, less best method achieve this purpose. As gold standard for GFR determination, urinary (or renal) clearance of inulin, fades into background due inconvenience and high cost, a diversity markers protocols compete replace it. In review, we suggest that iohexol, non-ionic contrast agent, most suited inulin as marker choice determination. Iohexol comes very close fulfilling...
The accuracy of estimation kidney function with the use routine metabolic tests, such as measurement serum creatinine level, has been controversial. European Kidney Function Consortium (EKFC) developed a creatinine-based equation (EKFC eGFRcr) to estimate glomerular filtration rate (GFR) rescaled level (i.e., is divided by median among healthy persons control for variation related differences in age, sex, or race). Whether cystatin C-based EKFC would increase estimated GFR unknown. We used...
We compared the risk of severe COVID-19 during two periods 2021 and 2022 when Delta Omicron, respectively, were dominating virus variants in Scania county, Sweden. adjusted for differences sex, age, comorbidities, prior infection vaccination. Risk disease from Omicron was markedly lower among vaccinated cases. It also unvaccinated but remained high (> 5%) older people middle-aged men with or more comorbidities. Efforts to increase vaccination uptake should continue.
Lack of functional telomeres can cause chromosomal aberrations. This type genetic instability may promote tumorigenesis. We have investigated the association between mean telomere length in buccal cells (assessed with quantitative real-time PCR) and bladder cancer risk a case–control study. Patients displayed significantly shorter than control subjects ( P = 0.001). Median ratio was 0.95 (range 0.53–3.2) for cases 1.1 (0.51–2.4) controls. Moreover, adjusted odds (OR) increased quartile...
We examined the influence of widely varied consumption fatty fish from Baltic Sea and age on plasma concentrations polychlorinated biphenyls (PCBs), polychlorobiphenylols (OH-PCBs), 2, 2-bis(4-chlorophenyl)-1,1,1-trichloroethane (4,4'-DDT), 2-bis(4-chlorophenyl)-1,1-dichloroethane (4,4'-DDE), 2,2',4, 4'-tetrabromodiphenyl ether (BDE-47), hexachlorobenzene (HCB), pentachlorophenol (PCP) in Latvian Swedish men. Both were significantly correlated with [sigman]PCB, [sigman]OH-PCB, 4,4'-DDE,...
Background: The performance of creatinine-based glomerular filtration rate (GFR) estimating equations may vary in subgroups defined by GFR, age and body mass index (BMI). This study compares the Modification Diet Renal Disease (MDRD) Chronic Kidney Epidemiology Collaboration (CKD-EPI) with revised Lund-Malmö equation (LM Revised), a new that can be expected to handle changes GFR across life span more accurately.
To increase the accuracy of estimated GFR (eGFR) from creatinine overall and at measured ≥90 mL/min per 1.73 m(2) by revising Lund-Malmö (LM) equations, to elaborate on more complex forms improve LM CKD-EPI equations further, assess benefits adding lean body mass (LBM).Swedish Caucasians (n = 850, 376 women; median 60, range 18-95 years) referred for measurement (plasma iohexol-clearance: 55, 5-173 mL/min/1.73 m(2)) constituted Study cohort. Bias, precision, accuracy, expressed as absolute...
This population study based on a representative sample from Swedish county investigates the prevalence, duration, and determinants of widespread pain (WSP) in using two constructs estimates how WSP affects work status. In addition, this prevalence its relationship to intensity, gender, age, income, status, citizenship, civil urban residence, health care seeking. A cross-sectional survey postal questionnaire was sent (n = 9952) target (284,073 people, 18–74 years) (Östergötland) southern...
Abstract Background Results from studies of road traffic noise and hypertension are heterogeneous with respect to effect size, effects among males females across age groups. Our objective was further explore these associations. Methods The study used cross-sectional public health survey data southern Sweden, including 24,238 adults (18 - 80 years old). We a geographic information system (GIS) assess the average (LAeq 24 hr) at current residential address. Effects on self-reported were...
Teachers are at high risk of stress-related disorders. This longitudinal study aimed to (a) identify which occupational, sociodemographic and life-style factors self-efficacy baseline that were importance for burnout, (b) explore associations between changes in the studied versus (c) by interviews increase understanding perceived job demands among teachers.A cohort 310 Swedish teachers school-years 4-9 responded a questionnaire factors, follow-up (mean 30 months later). A combined measure...
Hand eczema is more common in healthcare workers than the general population. Hands are subject to changing occupational exposures as a result of mandatory hygiene regulations for workers.To describe exposure procedures and investigate associations between hand washing, use nonsterile gloves disinfectant, self-reported eczema.This was cross-sectional study; an electronic questionnaire distributed 28 762 hospital employees southern Sweden. Nurses, assistant nurses or physicians constituted...