A5059205351- Glioma Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Meningioma and schwannoma management
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurobiology of Language and Bilingualism
- Speech and dialogue systems
- Intraoperative Neuromonitoring and Anesthetic Effects
- Radiomics and Machine Learning in Medical Imaging
- Moyamoya disease diagnosis and treatment
- Vestibular and auditory disorders
- Surgical site infection prevention
- Orthopedic Infections and Treatments
- Cerebral Venous Sinus Thrombosis
- Thin-Film Transistor Technologies
- Peripheral Artery Disease Management
- Vascular Malformations and Hemangiomas
- Botulinum Toxin and Related Neurological Disorders
- Aortic Disease and Treatment Approaches
- Advanced Neuroimaging Techniques and Applications
- Nanoplatforms for cancer theranostics
- Speech Recognition and Synthesis
- Management of metastatic bone disease
- Parkinson's Disease Mechanisms and Treatments
- Teratomas and Epidermoid Cysts
Tokyo Women's Medical University Yachiyo Medical Center
2021-2024
Tokyo Women's Medical University
2019-2024
Tokyo Women's Medical University Hospital
2022
Isesaki Fukushima Hospital
2020
Recurrent glioblastoma (GBM) remains one of the most challenging clinical issues, with no standard treatment and effective options. To evaluate efficacy talaporfin sodium (TS) mediated photodynamic therapy (PDT) as a new for this condition, we retrospectively analyzed 70 patients who underwent surgery PDT (PDT group) recurrent GBM 38 alone (control group). The median progression-free survival (PFS) in control groups after second was 5.7 2.2 months, respectively (p = 0.0043). overall (OS)...
Background Symptomatic cerebral vasospasm after subarachnoid hemorrhage (SAH) is a significant cause of delayed ischemia that leads to poor outcomes. Selective intra-arterial administration fasudil hydrochloride (IAF) has been adopted for its vasodilatory effect on spasm arteries prevent ischemia. However, clinical outcomes and predictive factors good recovery are not fully understood. This study aimed investigate the selective IAF identify in patients with SAH. Methods A retrospective 36...
Background: Bilateral vertebral artery dissection aneurysm (VADA) is a rare condition that leads to severe stroke. However, the surgical strategy for its treatment controversial because pathology very complicated and varies in each case. Here, we report case of bilateral VADA was successfully treated with staged occlusion low-flow bypass. Case Description: A Japanese man his 40s presented subarachnoid hemorrhage. He had only mild headaches without any other neurological deficits....
OBJECTIVE Neurosurgical ablation is an effective treatment for medically refractory motor symptoms of Parkinson’s disease (PD). A limited number studies have reported the effect pallidothalamic tract PD. In this study, authors evaluated safety and efficacy unilateral tractotomy akinetic-rigid (AR)–PD. METHODS Fourteen AR-PD patients, who were enrolled in prospective open-label underwent tractotomy. The Movement Disorder Society–Unified Disease Rating Scale (MDS-UPDRS) Part III IV (dyskinesia...
<title>Abstract</title> <bold>Purpose</bold>: Awake craniotomy presents a unique opportunity to map and preserve critical brain functions, particularly speech, during tumor resection. The ability accurately assess linguistic functions in real-time not only enhances surgical precision but also contributes significantly improving postoperative outcomes. However, today, its evaluation is subjective as it relies on clinician’s observations only. This paper explores the use of deep learning based...
<title>Abstract</title> <bold>Purpose</bold>: Awake craniotomy presents a unique opportunity to map and preserve critical brain functions, particularly speech, during tumor resection. The ability accurately assess linguistic functions in real-time not only enhances surgical precision but also contributes significantly improving postoperative outcomes. However, today, its evaluation is subjective as it relies on clinician’s observations only. This paper explores the use of deep learning based...
The primary goals of glioma surgery are maximal tumor resection and preservation brain function. Intraoperative motor-evoked potential (MEP) monitoring is commonly used to predict minimize postoperative paralysis. However, studies on intraoperative MEP trends paralysis scarce. This study aimed determine the relationship between
Cavernous malformations of the midbrain have a higher rate hemorrhage and poorer prognosis than vascular other brain areas. Surgical resection these lesions is often necessary to avoid neurological deficits in affected patients. Herein, literature surrounding cavernous was examined, case 48-year-old man with left hemiparesis diplopia caused by incomplete right oculomotor nerve palsy, who diagnosed from malformation, discussed. The lesion expanded gradually on magnetic resonance imaging...
Abstract BACKGROUND Surgical site infection(SSI) in neurosurgery can increase mortality and worsen functional outcome. There are few reports on risk factors for SSI glioma surgery. In this study, we investigated the surgery at our institution. METHODS We included 1013 patients with gliomas who underwent craniotomy between November 2013 March 2022 was defined as requiring surgical treatment. Various including age, gender, number of operations, prior radiology, chemotherapy, use intraoperative...
Abstract INTRODUCTION Glioblastoma has the worst prognosis of brain tumors. Evidence for improving by maximal tumor removal is being established, and in recent years, new treatments such as photodynamic therapy (PDT, 2014 Japan), TTF (2018) have been approved, treatment results are improving. In principle, our facility performs maximum using intraoperative MRI (iMRI) follow standard chemoradiation. Intraoperative PDT autologous vaccine (AFTV) will be given to desired patients. We...
Abstract Purpose Intraoperative magnetic resonance imaging (MRI) update navigation is performed in all cases to preserve neurological function and remove the tumor as much possible, prevent recurrence improve prognosis. And under awake craniotomy, we supported operators by integrating preoperative functional images with intraoperative MRI. We report our usefulness of image superimposition between medium field MRI position emission tomography (PET) diffusion tensor (DTI) color-map. Method Of...
Abstract Introduction Glioblastoma has the poorest prognosis among brain tumors, and most cases recur. On other hand, evidence of improvement by maximal surgical removal tumor is being established, in recent years, new treatments such as temozolomide (2006), photodynamic therapy (2014), TTF (2018) were approved insurance. patient outcome improved. In addition, molecular targeted (bevacizumab 2011) immunotherapy are also used clinical practice. this study, we retrospectively analyzed...
Abstract Background In the course of treatment malignant gliomas, appearance contrast-enhanced lesions and surrounding T2/FLAIR high-signal after is often experienced. There no modality that can reliably diagnose whether lesion a recurrence or response to treatment, including radiation necrosis. Furthermore, choice difficult, such as reexcision, stereotactic irradiation, Avastin. Very few reports have examined relationship between irradiation field histology. Methods Thirty-seven in 30...